Results 211 to 220 of about 241,974 (292)

Integration of 12-h time-restricted feeding with exercise training potentiates weight loss and attenuates MASLD in diet-induced obese mice. [PDF]

Sci Rep
Antonio GCF, Macêdo APA, Antunes GC, de Lima RD, da Silva Rios T, de Souza Pitoli B, Brisque GD, Dias LM, da Silva ASR, Cintra DE, Mekary RA, Ropelle ER, Chaix A, Pauli JR.   +13 more
europepmc   +1 more source

Studies on Experimental Obese Mice Part II Pathophysiology of Goldthioglucose Induced and Spontaneously Obese Mice

Folia Endocrinologica Japonica, 1965
openaire   +3 more sources

Integrative single cell RNA‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objectives Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell‐cell interactions in FAI and hip OA.
Gulzada Kulzhanova, Alexis Klee, Mina Botros, Victoria L. Hansen, John Reuter, Eliya Tazreena Tashbib, Eloise Fadial, Benjamin F. Ricciardi, Brian Giordano, Chia‐Lung Wu   +9 more
wiley   +1 more source

Female sex hormones do not drive the sex-specific mechanisms of obesity-related hypertension. [PDF]

Am J Physiol Heart Circ Physiol
Barris CT, Kress TC, Antonova G, Jordan CR, Newman A, Faulkner JL, Saeed MI, Kennard S, Belin de Chantemèle EJ.   +8 more
europepmc   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists, Sodium‐Glucose Cotransporter‐2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases

Arthritis &Rheumatology, Accepted Article.
Objective GLP‐1 receptor agonists (GLP‐1RAs) and SGLT2 inhibitors (SGLT2is) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear. We compared ARD incidence following initiation of GLP‐1RAs, or SGLT2is, vs.
Derin Karacabeyli, Diane Lacaille, Na Lu, Hui Xie, J. Antonio Aviña‐Zubieta   +4 more
wiley   +1 more source

Probiotic attributes and safety profile of AKM Lab-01: a novel <i>Akkermansia muciniphila</i> strain combating obesity and metabolic disorders in diet-induced obese mice. [PDF]

Front Microbiol
Huang B, Xian Y, Xue W, Pu Z, Kong P, Li P, Zhao Y, Tai L, Chen Z, Lan Z, Liu HW, Jiang X, Chen AJ.   +12 more
europepmc   +1 more source

Pharmacokinetics, pharmacodynamics and safety of vutiglabridin after multiple oral administrations in healthy female and obese subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims Vutiglabridin (HSG4112) is a novel drug under clinical development for antiobesity treatment. This study aimed to evaluate the pharmacokinetics (PKs) and safety of vutiglabridin after multiple oral administrations in healthy Korean female and obese subjects and explore short‐term pharmacodynamic (PD) responses.
Sooyoun Lee, Hyun Chul Kim, Young Ran Yoon, In‐Jin Jang, Sang‐Ku Yoo, Kyung‐Sang Yu   +5 more
wiley   +1 more source

The role of the gut non-bacterial microbiome (virome, mycobiome, archaeome) and its impact on obesity. [PDF]

Mol Metab
Chue KM, Wong SH, Zuo T, Ali Y.
europepmc   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source

Exploring the Anti‐Diabetic Potential of Anthocyanins: From Biochemical Pathways to Human Trials

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Diabetes mellitus (DM) is a global health challenge with increasing prevalence rates, particularly in low‐ and middle‐income countries. Anthocyanins (ACs) are potential bioactive compounds found in various fruits and vegetables, attracting the attention of researchers due to their possible role in managing diabetes and its complications ...
Lakshay Panchal, Sangeeta Yadav, Akash Kumar, Tanbeer Kaur, Yashna Bawa, Sarvesh Rustagi, Rahul Mehra   +6 more
wiley   +1 more source