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Studies on Experimental Obese Mice

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Energy Balances in Obese Mice

Annals of Nutrition and Metabolism, 1979
According to most existing theories, the regulation of energy balance is achieved by control of energy intake. This study was undertaken to find out whether there was control of energy output as well. Food intake, energy balance and the feed efficiency of weanling female mice made obese with injections of gold-thioglucose and monosodium glutamate ...
A, Djazayery, D S, Miller, M J, Stock
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Brain myelin of genetically obese mice

Journal of the Neurological Sciences, 1985
Brain myelin was studied in genetically obese (ob/ob) mice and compared with that of normal (+/+) mice from the same strain. The brain from obese mice had a significantly lower amount of myelin, and marked changes in the fatty acid composition of myelin were observed.
A, Sena, L L, Sarliève, G, Rebel
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Gastrointestinal apudosis in obese hyperglycaemic mice

Virchows Archiv B Cell Pathology, 1975
Quantitative histological and immunocytochemical studies have been carried out on the endocrine cells of the gastrointestinal tract in genetically obese mice and their heterozygous (lean) litter mates. In the ob/ob mice hyperplasia of most of the endocrine (APUD) cells of the gut was found, a condition which can be described as apudosis.
J M, Polak   +3 more
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Cholesterol metabolism in obese mice

Canadian Journal of Biochemistry, 1980
Young male obese mice and their lean litter mates (strain ob/ob) were compared. Serum cholesterol levels were higher in obese than in lean animals. 3-Hydroxy-3-methylglutaryl-CoA reductase activity was lower in brown adipose tissue and liver of obese mice than in tissue from their lean litter mates. However, activity of this enzyme was found to be the
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Diabetes-Obesity Syndromes in Mice

Diabetes, 1982
Several different rodent models are available for metabolic studies on the development of diabetes. Although the abnormalities associated with each diabetes type have many features in common, the documentation of several different genes being involved makes it unlikely that the various syndromes will be reduced to a single disturbance in one metabolic ...
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Zinc supplementation aggravates body fat accumulation in genetically obese mice and dietary-obese mice

Biological Trace Element Research, 1996
A perturbation of zinc metabolism has been noted in numerous laboratory animals with diabetes and obesity. The effects of zinc supplementation on body fat deposition in two types of experimental obese mice: genetically obese (ob/ob) mice and high-fat diet-induced ICR obese (HF) mice were investigated in this study. Their lean controls were +/?
M D, Chen, P Y, Lin, V, Cheng, W H, Lin
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