Results 261 to 270 of about 1,780,625 (304)

Responses to ozone are increased in obese mice

Journal of Applied Physiology, 2003
Epidemiological data indicate an increased incidence of asthma in overweight adults and children. Ozone (O3) is a common trigger for asthma. Accordingly, the purpose of this study was to compare O3-induced airway hyperresponsiveness and airway inflammation in lean, wild-type (C57BL/6J) mice and mice that are obese as a consequence of a genetic defect ...
S A, Shore, Y M, Rivera-Sanchez, I N, Schwartzman, R A, Johnston   +3 more
openaire   +2 more sources

The development of obesity in preweanling obob mice

British Journal of Nutrition, 1978
1. The body compositions of obob and lean (ob+ and + +) mice at 10, 12, 17 and 28 d of age were investigated using a ‘cold stress’ test to identify the two groups.2. At each of these ages the obob mice were found to contain significantly more fat than the lean. At 10 d 20 % more fat was present and by 17 d the increase was 72 %.
Thurlby, P L, Trayhurn, P
openaire   +2 more sources

Anti-obesity Effect of Phosphatidylinositol on Diet-Induced Obesity in Mice

Journal of Agricultural and Food Chemistry, 2010
The aim of this study is to investigate the biodistribution of phosphatidylinositol (PI) after oral administration and its anti-obesity effect. When a suspension of radiolabeled PI was orally administered to mice and the biodistribution was examined, PI radioactivity accumulated in the liver compared to myo-inositol radioactivity at 48 h or later after
Kosuke, Shimizu, Tomoko, Ida, Haruhito, Tsutsui, Tomohiro, Asai, Kazumasa, Otsubo, Naoto, Oku   +5 more
openaire   +2 more sources

Fatty Acid Mobilization in Obese Mice

Nature, 1970
PREPARATIONS of adipose tissue from obese hyperglycaemic mice of the C57B1/6J-ob strain have a reduced sensitivity to the fatty acid mobilizing activity of epinephrine1. Epinephrine is believed to exert its lipolytic effect by increasing the production of cyclic AMP2. This activates
openaire   +2 more sources

Mitochondrial proton leak in obesity-resistant and obesity-prone mice

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2007
We quantified uncoupling proteins (UCPs) in molar amounts and assessed proton conductance in mitochondria isolated from interscapular brown adipose tissue (IBAT) and hindlimb muscle [known from prior work to contain ectopic brown adipose tissue (BAT) interspersed between muscle fibers] of obesity-resistant 129S6/SvEvTac (129) and obesity-prone C57BL/6
Brian D, Fink, Judy A, Herlein, Katrine, Almind, Saverio, Cinti, C Ronald, Kahn, William I, Sivitz   +5 more
openaire   +2 more sources

Zinc supplementation aggravates body fat accumulation in genetically obese mice and dietary-obese mice

Biological Trace Element Research, 1996
A perturbation of zinc metabolism has been noted in numerous laboratory animals with diabetes and obesity. The effects of zinc supplementation on body fat deposition in two types of experimental obese mice: genetically obese (ob/ob) mice and high-fat diet-induced ICR obese (HF) mice were investigated in this study. Their lean controls were +/?
M D, Chen, P Y, Lin, V, Cheng, W H, Lin
openaire   +2 more sources

Antioxidant effects of melatonin on obese mice

Mutagenesis
Abstract Overweight and obesity have been increasing drastically in recent years due to the growing consumption of fast food. Obese individuals exhibit reduced antioxidant defenses, which can lead to DNA damage. Thus, studies have been conducted to mitigate obesity-related complications.
Luiza Martins, Longaretti, Marina Lummertz, Magenis, Adriani Paganini, Damiani, Ângela Caroline, da Luz Beretta, Isadora, de Oliveira Monteiro, Otávio Lúcio, Possamai, Gilson Pires, Dorneles, Alessandra, Peres, Gustavo, de Bem Silveira, Paulo César Lock, Silveira, Vanessa Moraes, de Andrade   +10 more
openaire   +2 more sources

Obesity in Mice and Men

Obesity Research, 2001
B R, Bistrian, K C, McCowen
openaire   +2 more sources

Studies on Obesity I. Nutritional Obesity in Mice

The Journal of Nutrition, 1953
P F, FENTON, M T, DOWLING
openaire   +2 more sources

Scrapie-Induced Obesity in Mice

Journal of Infectious Diseases, 1987
Y S, Kim, R I, Carp, S M, Callahan, H M, Wisniewski   +3 more
openaire   +2 more sources