Results 151 to 160 of about 70,603 (247)

Submicron-sized ultrasound contrast agents as therapeutic peptide delivery vehicles in type 1 diabetes. [PDF]

Theranostics
Ciccaglione M, Abenojar E, Kosmides T, DiLisio JE, McDaniel KA, Hartmoore K, Gresch A, Jarrell DK, Ramirez DG, Sticco-Ivins M, Michels AW, Haskins K, Exner AA, Benninger RKP.   +13 more
europepmc   +1 more source

Therapeutic potential of spexin in diabetic neuropathy: Insights from in vitro and in vivo models

Experimental Physiology, Volume 111, Issue 8, Page 3800-3817, 1 August 2026.
Abstract The present study investigated the therapeutic potential of spexin (SPX) on both in vitro and in vivo models of diabetic neuropathy (DN). A total of 40 male BALB/c mice were randomly allocated into four experimental groups (n = 10 per group): a normoglycaemic control, an untreated DN group and two SPX treatment groups (DN+SPX‐12.5 and DN+SPX ...
Mehmet Refik Bahar, Seval Ulku Orhan, Cigdem Tekin, Asli Taslidere, Mete Ozcan, Suat Tekin   +5 more
wiley   +1 more source

Next-Generation Strategies for Neural Repair and Regeneration: Neural Organoid Transplantation in the CNS. [PDF]

Cell Prolif
Wang Y, Li J, Mao X, Wang W, Li Y, Hu X, Zhong J, Zhao F, Wang L.   +8 more
europepmc   +1 more source

Protein kinase Cδ and pharmacomechanical coupling: Re‐envisioning cerebral vascular control

The Journal of Physiology, Volume 604, Issue 15, Page 6324-6347, 1 August 2026.
Abstract figure legend Top, G‐protein coupled receptors trigger electromechanical and pharmacomechanical coupling, the latter via signal transduction pathways that inhibit myosin light chain phosphatase. Middle, the relative contribution of electromechanical and pharmacomechanical coupling varies with the concentration and the vessel area to which ...
Nadia Haghbin, Michelle S. M. Kim, Mohammed El‐lakany, David M. Richter, Dabasish Kumar Saha, Galina Yu. Mironova, David A. Steven, Jonathan C. Lau, Mel Boulton, Nikolaos M. Tsoukias, Donald G. Welsh   +10 more
wiley   +1 more source

<i>Borrelia mayonii</i> induces carditis but not arthritis in Lyme-susceptible mice. [PDF]

Front Immunol
Cleveland DW, Wijetunga N, Casselli T, Tourand Y, Pecoraro HL, Brissette CA.   +5 more
europepmc   +1 more source

BCL‐2 and MCL1 co‐inhibition enhances glucocorticoid therapy in preclinical models of infant KMT2A‐rearranged acute lymphoblastic leukaemia

British Journal of Haematology, Volume 209, Issue 2, Page 786-792, August 2026.
Mawar Karsa, Ayu Karsa, Dayna Spurling, Lin Xiao, Emma Ronca, Angelika Bongers, Weiman Gao, Andrew J. Gifford, Ali El‐Ayoubi, Laurence C. Cheung, Rishi S. Kotecha, Richard B. Lock, Charis E. Teh, Guillaume Lessene, Murray D. Norris, Andrew Wei, Michelle Haber, Michelle J. Henderson, Donia M. Moujalled, Klaartje Somers   +19 more
wiley   +1 more source

A high‐fat, high‐sucrose diet exacerbates muscle and metabolic pathology and undermines glucocorticoid efficacy in dystrophin‐deficient mice

The Journal of Physiology, Volume 604, Issue 15, Page 6440-6464, 1 August 2026.
Abstract figure legend A high‐fat, high‐sucrose diet (HFHSD) exacerbated muscle and metabolic dysregulation in mdx mice while also altering the physiological response to prednisolone (Pred) In diaphragms of control diet (CD)‐fed mdx mice, prednisolone treatment improved muscle function and reduced fibrosis, inflammatory signalling, and mitochondrial ...
Morgan E. Vorwald, Swathy Krishna, Ji Heun Lee, Melissa Roths, Rudy J. Valentine, Joshua T. Selsby   +5 more
wiley   +1 more source

Assessment of three antiviral compounds against Borealpox virus infection in a mouse model. [PDF]

Emerg Microbes Infect
Prévost J, Tailor N, Sloan A, Fulton K, Medina SJ, Audet J, Soule G, Safronetz D.   +7 more
europepmc   +1 more source

Pancreatic cancer cachexia promotes cardiac dysfunction through altered adrenergic signalling in the heart

The Journal of Physiology, Volume 604, Issue 15, Page 6281-6301, 1 August 2026.
Abstract figure legend The β1‐adrenergic receptor is the predominant adrenergic subtype expressed on cardiac myocytes. Upon stimulation it activates downstream signalling pathways that increase the heart rate and cardiac output to meet metabolic demands.
Parham Diba, Peter R. Levasseur, Samuel D. Newton, Khia Min Sabrina Koh, Paige C. Arneson‐Wissink, Xinxia Zhu, Peter Pham, Heike Mendez, Luke Whitcomb, Ariana Sattler, William R Woodward, Beth A. Habecker, Daniel L. Marks, Aaron J. Grossberg   +13 more
wiley   +1 more source

An update on inborn errors of V(D)J recombination. [PDF]

Physiology (Bethesda)
Schim van der Loeff I, Ahuja M, Chen R, Patane E, Hambleton S.   +4 more
europepmc   +1 more source