Results 11 to 20 of about 70,603 (247)

Helicobacter-associated gastritis in SCID mice [PDF]

open access: yesInfection and Immunity, 1995
Immunodeficient (SCID) and immunocompetent mice were infected with Helicobacter felis to address the role of autoimmunity in Helicobacter-associated gastritis. The extents of inflammation were equivalent in the two groups. The numbers of H. felis organisms were marginally increased in the SCID mice but did not achieve statistical significance.
T G, Blanchard   +3 more
openaire   +2 more sources

Rescue of Fertility in Homozygous Mice for the Urokinase Plasminogen Activator Transgene by the Transplantation of Mouse Hepatocytes

open access: yesCell Transplantation, 2008
Development of the urokinase plasminogen activator/SCID (uPA/SCID) transgenic mouse model has opened new perspectives for the study of different biological mechanisms such as liver regeneration, stem cell differentiation, and human hepatic pathogens.
Nicolas M. Brezillon   +7 more
doaj   +1 more source

Hantavirus Infection in SCID Mice.

open access: yesJournal of Veterinary Medical Science, 1997
Severe combined immunodeficiency (SCID) mice were inoculated with Hantaan virus strain 76-118 (HTN) or Seoul virus strain SR-11 (SR) of hantaviruses. Susceptibility of SCID mice was compared with those of immunocompetent adult mice, newborn mice and nude mice. SCID mice inoculated with HTN or SR died 32 to 35 days after infection.
YOSHIMATSU, Kumiko   +3 more
openaire   +3 more sources

Fracture Healing Is Delayed in Immunodeficient NOD/scid‑IL2Rγcnull Mice. [PDF]

open access: yesPLoS ONE, 2016
Following bone fracture, the repair process starts with an inflammatory reaction at the fracture site. Fracture healing is disturbed when the initial inflammation is increased or prolonged, whereby, a balanced inflammatory response is anticipated to be ...
Anna E Rapp   +8 more
doaj   +1 more source

Differentiation of Uterine Natural Killer Cells in Pregnant SCID (scid/scid) Mice

open access: yesJournal of Veterinary Medical Science, 2011
To determine whether functional T- and B-cells can affect differentiation and/or proliferation of uterine natural killer (uNK) cells, their numbers in SCID mice (genotype, C.B.-17/Icr-scid/scid) were compared with those of control mice (genotype, C.B.-17/Icr-+/+) on days 8, 12 and 16 of pregnancy.
HIYAMA, Masato   +5 more
openaire   +3 more sources

Mitochondrial Autophagy and NLRP3 Inflammasome in Pulmonary Tissues from Severe Combined Immunodeficient Mice after Cardiac Arrest and Cardiopulmonary Resuscitation

open access: yesChinese Medical Journal, 2018
Background: The incidence of cancer, diabetes, and autoimmune diseases has been increasing. Furthermore, there are more and more patients with solid organ transplants.
Jing-Jun Lyu   +8 more
doaj   +1 more source

Differential post-surgical metastasis and survival in SCID, NOD-SCID and NOD-SCID-IL-2Rγ(null) mice with parental and subline variants of human breast cancer: implications for host defense mechanisms regulating metastasis. [PDF]

open access: yesPLoS ONE, 2013
We compare for the first time, the metastatic aggressiveness of the parental MDA-MB-231 breast cancer cell line and two luciferase-tagged in vivo-derived and selected pro-metastatic variants (LM2-4/luc⁺ and 164/8-1B/luc⁺ in SCID, NOD-SCID and NOD-SCID-IL-
Chloe C Milsom   +4 more
doaj   +1 more source

Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID

open access: yesMolecular Therapy: Methods & Clinical Development, 2020
Recombinase-activating gene-1 (RAG1)-deficient severe combined immunodeficiency (SCID) patients lack B and T lymphocytes due to the inability to rearrange immunoglobulin and T cell receptor genes.
Laura Garcia-Perez   +21 more
doaj   +1 more source

Outcome of Xenografted Fetal Porcine Pancreatic Tissue is Superior in Inbred Scid (C.B-17/Icr-scid/scid) Compared to Outbred Nude (CD-1-nu/nu) Mice

open access: yesCell Transplantation, 1999
Nude mice are used as recipients of foreign tissue because of their inability to reject these grafts. Our experience has been that there is variable rejection of fetal porcine insulin-producing tissue transplanted into CD-1 (athymic) outbred nude mice ...
Bernard E. Tuch Ph.D.   +1 more
doaj   +1 more source

Data in support of the bone analysis of NOD–SCID mice treated with zoledronic acid and prednisolone

open access: yesData in Brief, 2016
This paper reports data on the bone, specifically the tibia and mandible, of nonobese diabetic mice with severe combined immunodeficiency disease (NOD–SCID mice) treated with zoledronic acid (ZA) and prednisolone (PSL).
Naoko Hori   +6 more
doaj   +1 more source

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