Results 231 to 240 of about 1,897,120 (285)

Upregulating ANKHD1 in PS19 Mice Reduces Tau Phosphorylation and Mitigates Tau Toxicity-Induced Cognitive Deficits. [PDF]

Int J Mol Sci
Tian X, Le N, Zhao Y, Alawamleh D, Schwartz A, Meyer L, Helm E, Wu C.   +7 more
europepmc   +1 more source

Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial‐Neural Axis

Advanced Science, EarlyView.
The authors develop mouse models by mimicking peripheral vascular diseases, combining multiple strategies and transgenic mouse lines, to demonstrate that ECs, but not macrophages or SMCs, play an active role mediated by endothelial ET‐1/neural ETAR signaling and beyond endothelial homeostatic angiocrine by driving protective pain through the ...
Zuo‐Jie Jiang, Di Mu, Su Liu, Peng‐Bo Jing, Bin Wu, Xiao‐Mei Yang, Jia‐Yi Ge, Qing‐Yi Li, Hao‐Hao Chen, Feng‐Ming Zhang, Bing Wang, Ying‐Ying Zhang, Linnan Qian, Zi‐Yi Zhu, Yu‐Sen Ou, Shi‐Yu Sun, Lin Luo, Yu Feng, Changyu Jiang, Zhuo Sun, Yong Chen, Hai‐Li Pan, Bin Wang, Fen‐Fei Gao, Jie Wu, Zhigang Lu, Tong Liu, Yan‐Gang Sun, Xing‐Jun Liu   +28 more
wiley   +1 more source

Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids

Advanced Science, EarlyView.
To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun, Lifa Zhu, Yutong Li, Jinyan Tang, Tao Zhang, Hengjia Zhang, Wanchu Wang, Lufan Li, Shuhui Bian, Xin Wu   +9 more
wiley   +1 more source

Transgenic augmentation of erythroferrone in mice ameliorates anemia in adenine-induced chronic kidney disease. [PDF]

JCI Insight
Czaya B, Olivera JD, Zhang M, Lundin A, Castro CD, Jung G, Hanudel MR, Nemeth E, Ganz T.   +8 more
europepmc   +1 more source

Correction: Severe enterovirus A71 pathogenesis and immune responses in human nucleolin transgenic mice. [PDF]

Med Microbiol Immunol
Hsiao NE, Wang YF, Lin YC, Chou WT, Hsu LJ, Wang SM, Wang JR, Lai MD, Chen SH, Chang CF.   +9 more
europepmc   +1 more source

Bladder Dysfunction in Sickle Cell Disease Is Associated with Inflammation and Oxidative Stress. [PDF]

Int J Mol Sci
Pereira DA, Calmasini FB, Silveira THR, Pereira DA, de Oliveira MG, Costa FF, Silva FH.   +6 more
europepmc   +1 more source

Facilitated α-synuclein oligomer sharing among glial cells by a centrally acting connexin inhibitor attenuates a rapidly progressive multiple system atrophy-cerebellar type model by reducing the neuronal α-synuclein burden. [PDF]

Acta Neuropathol Commun
Harada M, Masaki K, Tanaka T, Sekiya H, Matsuse D, Yamaguchi H, Nishimura Y, Takase EO, Tanaka E, Kira YI, Fujishima K, Matsuo E, Yamasaki R, Dickson DW, Suzumura A, Taniwaki T, Hoshino T, Isobe N, Takeuchi H, Kira JI.   +19 more
europepmc   +1 more source

Humanized Mouse Models for Type 1 Diabetes. [PDF]

Curr Protoc
Serreze DV, Tousey-Pfarrer M, Racine JJ.
europepmc   +1 more source

Mouse models of type I interferonopathies. [PDF]

Hum Mol Genet
Luca D, Kato H.
europepmc   +1 more source

Identification of protective human monoclonal antibodies using a K18 hACE2 transgenic mouse SARS-CoV-2 challenge model

Borate B, Pino PA, Hicks A, Garcia JI, Garcia-Vilanova A, Ye C, Park J, Maingot B, Rodriguez O, Saveria T, Holman D, Schendel SL, Saphire EO, Martinez-Sobrido L, Torrelles JB, Fiore-Gartland A.   +15 more
europepmc   +1 more source