Results 91 to 100 of about 6,887,725 (399)

The gut microbiota influences skeletal muscle mass and function in mice

open access: yesScience Translational Medicine, 2019
Transplanting the gut microbiota of pathogen-free mice into germ-free mice improves skeletal muscle mass and strength. Of microbial metabolites and muscle Skeletal muscle is important not only for locomotion but also for regulating metabolic function ...
Shawon Lahiri   +18 more
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Policies to Promote Medical Tourism in Korea: A Narrative Review

open access: yesIranian Journal of Public Health, 2018
Background: There is a growing global demand for medical tourism while more people are moving across borders in Asia, offering new opportunities to the high-value medical tourism market.
Byung Ro SEO, Sam-Hun PARK
doaj  

Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota

open access: yesScientific Reports, 2017
Alzheimer’s disease is the most common form of dementia in the western world, however there is no cure available for this devastating neurodegenerative disorder. Despite clinical and experimental evidence implicating the intestinal microbiota in a number
T. Harach   +10 more
semanticscholar   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension

open access: yesAdvanced Science
Refractory hypertension often involves centrally driven sympathetic augmentation. Yet effective central targets for the treatment of hypertension are still scarce.
Ying Shi   +18 more
doaj   +1 more source

Tourist behaviors and needs for the development of creative Thai traditional sports tourism marketing for special interest tourism [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2020
This study aimed to investigate tourist behaviors and needs for the development of creative Thai traditional sports tourism to support special interest tourism.
Asst. Prof. Dr. Thirachaya Chaigasem   +1 more
doaj  

Laboratory mice born to wild mice have natural microbiota and model human immune responses

open access: yesScience, 2019
Born to be a wildling Inbred laboratory mouse strains are used extensively in basic and translational immunology research. However, the commensal and pathogenic repertoire of resident microbes encountered in the wild is not replicated in a lab setting ...
S. Rosshart   +25 more
semanticscholar   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

The effect of environment on post surgical overall well-being and pain sensitivity in an animal model [PDF]

open access: yes, 2016
With chronic post surgical pain affecting up to one third of patients undergoing surgeries and the price of treatment being astoundingly high there has been a transition in research to investigate and identify risk factors. Through identification of risk
Reddy, Archana
core   +1 more source

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