Results 91 to 100 of about 4,155,608 (362)

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Progress of the MICE experiment [PDF]

open access: yesarXiv, 2015
The international Muon Ionization Cooling Experiment (MICE) will perform a systematic investigation of ionization cooling of a muon beam. The demonstration is based on a simplified version of a neutrino factory cooling channel. As the emittance measurement will be done on a particle-by-particle basis, sophisticated beam instrumentation has been ...
arxiv  

High blood levels of IL-6 nicely correlate with animal survival in trained C26 bearing mice [PDF]

open access: yes, 2015
Exercise is a beneficial adjunct therapy to maintain or enhance quality of life in cancer patients. Recently, few studies demonstrated a correlation between high concentrations of IL-6 and a poor survival.
Adamo, Sergio   +9 more
core   +2 more sources

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Management for the transformation of a Historical City into a MICE City supporting the idea of MICE business in AEC. [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2019
This mixed method research investigated the measures that had been taken in order to transform a historical city into a MICE city in order to cater to MICE business, which has been rampaging under the prevailing AEC.
Asst. Prof. Dr. Thirachaya Chaigasem
doaj  

Ready to be a host?: The potential development guidelines of sport tourism in Buriram Province, Thailand [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2020
Tourism is a major industry in the world. Sport tourism is considered to be a part of tourism created through of the integration of sports and tourism.
Asst. Prof. Dr. Thirachaya Chaigasem   +1 more
doaj  

Increased Metabolic Rate in X-linked Hypophosphatemic Mice [PDF]

open access: yes, 1986
Hyp mice are a model for human X-linked hypophosphatemia, the most common form of vitamin D-resistant rickets. It has previously been observed that Hyp mice have a greater food consumption per gram body weight than do normal mice.
Meyer, M. H.   +2 more
core   +1 more source

Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179 [PDF]

open access: yes, 2015
The rd1 mouse with a mutation in the Pde6b gene was the first strain of mice identified with a retinal degeneration. However, AAV-mediated gene supplementation of rd1 mice only results in structural preservation of photoreceptors, and restoration of the ...
Ali, RR   +11 more
core   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

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