Results 221 to 230 of about 4,155,608 (362)

The pathogenicity for mice of group B streptococci of bovine origin [PDF]

, 1949
I.H. Pattison
openalex   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

FEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang, Yukun Xu, Yujia Li, Yiming Pang, Xueting Ding, Raorao Zhou, Dan Liang, Xianda Che, Yuanyu Zhang, Chunfang Wang, Wenjin Li, Pengcui Li   +11 more
wiley   +1 more source

Pitolisant alleviates brain network dysfunction and cognitive deficits in a mouse model of Alzheimer's disease. [PDF]

Transl Psychiatry
Zou Y, Yang L, Zhu J, Fan J, Zheng H, Liao X, Yang Z, Zhang K, Jia H, Konnerth A, Wang YJ, Zhang C, Zhang Y, Li SC, Chen X.   +14 more
europepmc   +1 more source

THE INFECTION OF MICE WITH SWINE INFLUENZA VIRUS [PDF]

, 1935
Richard E. Shope
openalex   +1 more source

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, EarlyView.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

Correction: TSG101 depletion dysregulates mitochondria and PML NBs, triggering MAD2-overexpressing interphase cell death (MOID) through AIFM1-PML-DAXX pathway

Cell Death and Disease
Yao Xi, Rui Xu, Shengnan Chen, Jiezhu Fang, Xiang Duan, Yidan Zhang, Guoli Zhong, Zhifei He, Yan Guo, Xinyu Li, Wenzhi Tao, Yang Li, Yan Li, Lei Fang, Yohei Niikura   +14 more
doaj   +1 more source

Neuronal CDK5RAP3 deficiency leads to encephalo-dysplasia via upregulation of N-glycosylases and glycogen deposition. [PDF]

Cell Death Discov
Chen F, Xiang M, Wang Z, Yang F, Zhou J, Deng Z, Wang S, Li P, Tew J, Zhang W, Li H, Teng Y, Zhu X, Cai Y.   +13 more
europepmc   +1 more source

STUDIES OF THE MECHANISM OF ACTION OF URETHANE IN INITIATING PULMONARY ADENOMAS IN MICE [PDF]

, 1957
Stanfield Rogers
openalex   +1 more source

Comparative activity of dimethyl fumarate derivative IDMF in three models relevant to multiple sclerosis and psoriasis

FEBS Open Bio, EarlyView.
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He, Guiyi Gong, Geovani Quijas, Simon Ming‐Yuen Lee, Ratan K. Chaudhuri, Krzysztof Bojanowski   +5 more
wiley   +1 more source

A cell-type-specific circuit of somatostatin neurons in the habenula encodes antidepressant action in male mice. [PDF]

Nat Commun
Luo L, Jing W, Guo Y, Liu D, He A, Lu Y.
europepmc   +1 more source