Results 181 to 190 of about 72,556 (306)

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini   +9 more
wiley   +1 more source

Structure-dependent incorporation of terpenes into amphiphilic Poly(2-oxazoline) micelles. [PDF]

open access: yesBiomed Microdevices
Palchak L   +4 more
europepmc   +1 more source

Matching TGF‐β1 Activation With Stress‐Responsive Charge‐Reversal Hydrogel Microspheres for the Treatment of Osteoarthritis

open access: yesExploration, EarlyView.
Based on the interaction between the weakly cross‐linked disulfide bonds that break under stress and charge‐reversal messenger molecules, we herein achieved nanoparticle charge reversal under stress and constructed a stress‐responsive charge‐reversal hydrogel microsphere system using microfluidic technology.
Feng Lin   +11 more
wiley   +1 more source

Decoding the Conformation of Polylactic Acid in Block Copolymer Micelles. [PDF]

open access: yesJ Am Chem Soc
Muñoz-López J   +7 more
europepmc   +1 more source

Enhancing Optogenetics‐Based Cancer Therapy Via Nanotechnology

open access: yesExploration, EarlyView.
Nanotechnology enhances optogenetics‐based cancer therapy through improved delivery systems and non‐invasive optical regulation. It further enables precise and programmable control of optogenetic living therapeutics for localized antitumor responses.
Honggang Shen   +8 more
wiley   +1 more source

Hydrophilic Janus Micelles From an ABC Triblock Copolymer. [PDF]

open access: yesAngew Chem Int Ed Engl
Muñoz-López J   +5 more
europepmc   +1 more source

Customizing 3D Hierarchically Macroporous Covalent Organic Framework Superstructures for Improved Biosensing Interface in Highly‐Sensitive Electrochemical Biosensors

open access: yesExploration, EarlyView.
The 3D hierarchically macroporous COF superstructure, which demonstrates enhanced mass and charge transfer along with superior substrate enrichment at the biosensing interface, serves as an advanced electrode material for enzyme immobilization.
Wenbo Wei   +8 more
wiley   +1 more source

Smart Nanodelivery Systems for Immunometabolic Modulation in Osteoarthritis

open access: yesExploration, EarlyView.
Smart nanodelivery systems deliver therapeutic payloads across the cartilage matrix to ensure their sustained accumulation within chondrocytes at sites of injury. By targeting specific molecular targets and signaling pathways, these platforms modulate the pathological synovium‐cartilage axis to restore immunometabolic homeostasis and drive tissue ...
Qirui Zhao   +20 more
wiley   +1 more source

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