Results 121 to 130 of about 222,369 (326)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

open access: yesAdvanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode   +16 more
wiley   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

open access: yesAdvanced Materials Interfaces, EarlyView.
xx xx. ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation ...
Tang Yuqing   +5 more
wiley   +1 more source

Engineering Docetaxel Micelles for Enhanced Cancer Therapy Through Intermolecular Forces

open access: yesBioengineering
Docetaxel has exhibited excellent therapeutic effects in cancer treatment; however, its hydrophobicity, short blood circulation time, and high blood toxicity restrict its clinical application.
Hao Wang   +9 more
doaj   +1 more source

Infusion pasteurization of skim milk: Effects of different time-temperature combinations [PDF]

open access: yes, 2007
Infusion pasteurization technology was used in different time-temperature combinations for heat treatment of skim milk and compared to untreated skim milk and a standard pasteurization treatment.
Hammershøj, M.   +2 more
core  

Membrane Semi‐Permeability and Ion Selectivity in Chemiosmosis: Open Systems Volume Dependence of Electrolyte Chemistry

open access: yesAdvanced Materials Interfaces, EarlyView.
Very small cellular compartments can break electroneutrality and harness proton gradients without active transport structures, whereas larger volumes cannot, underscoring why life's critical energy processes are confined in microscopic spaces. ABSTRACT The effect of pH changes in external ionic solutions on liposomes entrapping non‐permeable weak acid ...
Josep M. Ribó   +4 more
wiley   +1 more source

Crystalline free energies of micelles of diblock copolymer solutions

open access: yes, 2010
We report a characterization of the relative stability and structural behavior of various micellar crystals of an athermal model of AB-diblock copolymers in solution.
Abramowitz M.   +6 more
core   +1 more source

Room Temperature Synthesis and Photopatterning of Mesoporous Titanium Dioxide Thin Films

open access: yesAdvanced Materials Technologies, EarlyView.
A nanofabrication strategy combining deep‐UV photolithography with block copolymer self‐assembly enables direct patterning and mineralization of mesoporous TiO2 thin films at room temperature. Photocatalytic titanium oxo‐clusters promote polymer degradation under UV irradiation, enabling multiscale control over porosity, film thickness, and lateral ...
Youssef Ghossoub   +5 more
wiley   +1 more source

Preparation and evaluation of novel mixed micelles as nanocarriers for intravenous delivery of propofol

open access: yesNanoscale Research Letters, 2011
Novel mixed polymeric micelles formed from biocompatible polymers, poly(ethylene glycol)-poly(lactide) (mPEG-PLA) and polyoxyethylene-660-12-hydroxy stearate (Solutol HS15), were fabricated and used as a nanocarrier for solubilizing poorly soluble ...
Li Xinru   +7 more
doaj  

Ultra-small micelles based on polyoxyl 15 hydroxystearate for ocular delivery of myricetin: optimization, in vitro, and in vivo evaluation

open access: yesDrug Delivery, 2019
The aim was to develop a nanocarrier based on polyoxyl 15 hydroxystearate (Kolliphor® HS15, HS15) micelles for the solubility, stability, and ocular delivery of myricetin (Myr).
Yuzhen Hou   +7 more
doaj   +1 more source

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