Results 131 to 140 of about 209,966 (301)

Cationic micelles prepared by amphiphilic chitosan derivatives for siRNA delivery

open access: yes, 2008
Abastract In the last decade, a lot of studies on preparation of varied nanocarriers with cationic polymers such as PEI, PLL, chitosan and their derivatives have been reported for DNA and siRNA delivery [1].
周火飞, 刘袖洞, 马小军
core  

C‐Terminal Nucleobase Modification Amplifies Peptide‐Mediated Liposome Fusion

open access: yesChemistry – A European Journal, EarlyView.
Let's come together right now. Cationic peptides are known to promote aggregation of negatively charged liposomes through electrostatic interaction. The process is reversible: once neutrality is achieved, liposomes disaggregate. Here, we demonstrate that end‐capping peptides with nucleobases turns the process into irreversible fusion.
Laura Morbiato   +4 more
wiley   +1 more source

Self‐Immolative Gels: Programmable Degradation Using Self‐Immolative Linkers and Polymers

open access: yesChemistry – A European Journal, EarlyView.
Self‐immolative linkers and polymers undergo bond‐cleaving reaction cascades in response to specific stimuli. Their incorporation into gels can be harnessed to release cargo, induce property changes, or trigger degradation in a highly controlled manner. These functions can be employed in applications such as sensing and drug delivery.
Chuanfeng Li, Elizabeth R. Gillies
wiley   +1 more source

Cinnamaldehyde and cinnamaldehyde-containing micelles induce relaxation of isolated porcine coronary arteries: role of nitric oxide and calcium

open access: yes, 2014
Gábor Raffai,1 Byungkuk Kim,1 Sanga Park,1 Gilson Khang,1 Dongwon Lee,1 Paul M Vanhoutte1,21World Class University, Department of BIN Fusion Technology, Chonbuk National University, Jeonju, Jeonbuk, South Korea; 2Department of Pharmacology and ...
Khang G   +5 more
core  

Enzymatic Prenylation of Proteins and Peptides: From Cysteine S‐Prenylation to Tryptophan‐Selective Biocatalysis

open access: yesChemistry – A European Journal, EarlyView.
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami   +2 more
wiley   +1 more source

Poloxamer 407/TPGS mixed micelles for delivery of gambogic acid to breast and multidrug-resistant cancer

open access: yes, 2012
Vipin Saxena, M Delwar HussainDepartment of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Kingsville, TX, USABackground: Delivery of a high concentration of anticancer drugs specifically to ...
Saxena V, Hussain MD
core  

A full-active phosphorus dendron-based nanomedicine alleviates ischemic stroke through multi-target immunomodulation and neuroprotection. [PDF]

open access: yesBioact Mater
Zhang C   +10 more
europepmc   +1 more source

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