Results 121 to 130 of about 117,565 (253)

Folic acid-functionalized drug delivery platform of resveratrol based on Pluronic 127/D-α-tocopheryl polyethylene glycol 1000 succinate mixed micelles

International Journal of Nanomedicine, 2017
Jifu Hao,* Tiantian Tong,* Kai Jin, Qiannan Zhuang, Te Han, Yanping Bi, Jianzhu Wang, Xiaodan Wang College of Pharmacy, Taishan Medical University, Taian, People’s Republic of China *These authors contributed equally to this work Abstract: A ...
Hao J, Tong T, Jin K, Zhuang Q, Han T, Bi Y, Wang J, Wang X   +7 more
doaj  

MRI-detectable polymeric micelles incorporating platinum anticancer drugs enhance survival in an advanced hepatocellular carcinoma model

, 2015
Nguyen Quoc Vinh,1 Shigeyuki Naka,1 Horacio Cabral,2 Hiroyuki Murayama,1 Sachiko Kaida,1 Kazunori Kataoka,2 Shigehiro Morikawa,3 Tohru Tani4 1Department of Surgery, Shiga University of Medical Science, Shiga, Japan; 2Department of Bioengineering ...
Morikawa S, Vinh NQ, Kataoka K, Cabral H, Kaida S, Tani T, Naka S, Murayama H   +7 more
core  

Decoration of pH-sensitive copolymer micelles with tumor-specific peptide for enhanced cellular uptake of doxorubicin [PDF]

, 2016
Qing Chen,1,* Miaomiao Long,2,* Lipeng Qiu,3 Mengqin Zhu,3 Zhen Li,1 Mingxi Qiao,1 Haiyang Hu,1 Xiuli Zhao,1 Dawei Chen1 1Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 2Department of Research and ...
Chen Q, Qiu LP, Li Z, Long MM, Hu HY, Qiao MX, Zhao XL, Zhu MQ, Chen DW   +8 more
core  

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

Advanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou, Lei Zhang, Xingyu Cai, Jiajia Su, Guangyu Dai, Xue Chen, Hanming Wang, Jia Hua, Jianping Liu, Chunmeng Sun, Xiancheng Chen, Erhao Wang, Wenli Zhang   +12 more
wiley   +1 more source

Glioma-targeting micelles for optical/magnetic resonance dual-mode imaging

, 2015
Qing Zhou,1,* Ketao Mu,2,* Lingyu Jiang,1 Hui Xie,3 Wei Liu,1 Zhengzheng Li,1 Hui Qi,1 Shuyan Liang,1 Huibi Xu,1 Yanhong Zhu,1 Wenzhen Zhu,2 Xiangliang Yang11National Engineering Research Center for Nanomedicine, College of Life Science and Technology ...
Liang S, Yang X, Jiang L, Li Z, Zhou Q, Xie H, Zhu Y, Qi H, Mu K, Zhu W, Xu H, Liu W   +11 more
core  

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

Advanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu, Kang Wang, Kwet Kyawl Yan, Zhikai Xu, Xuan Zhao, Xiangjun Bai, Zhanfei Li, Yuchang Wang   +7 more
wiley   +1 more source

Expanding the DNA Nanotechnology Toolbox: Hierarchical Assembly and Self‐Sorting of DNA Tiles With Precisely Controlled Hydrophobic Behavior

Angewandte Chemie, EarlyView.
DNA tile amphiphiles encode dual chemical information, directing nanostructure formation through base‐pairing and hydrophobic effects. Thermal annealing programs hierarchical assembly, with first‐formed interactions biasing the final morphology: short hydrophobic chain strands form DX‐tiles and then into stars, while long‐chain strands form SNAs and ...
Yihao Wu, Muhammad Ghufran Rafique, Christopher Saab, Hanadi Sleiman   +3 more
wiley   +2 more sources

Biodegradable polymeric micelles coencapsulating paclitaxel and honokiol: a strategy for breast cancer therapy in vitro and in vivo

, 2017
Ning Wang, Zhihan Wang,* Shihong Nie,* Linjiang Song, Tao He, Suleixin Yang, Xi Yang, Cheng Yi, Qinjie Wu, Changyang Gong State Key Laboratory of Biotherapy and Cancer Center, Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan ...
Song L, Yang X, Wang N, Nie S, He T, Gong C, Wu Q, Yi C, Wang Z, Yang S   +9 more
core  

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

Click'n ROPISA: One‐Pot Synthesis of Ultrabright Fluorescent Nanoparticles Made of Polypeptides

Angewandte Chemie, EarlyView.
Self‐assembly and fluorophore conjugation proceed rapidly in a one‐pot “Click'n ROPISA” process, yielding intensely fluorescent polypeptide nanoparticles with tunable visible emission. High dye loading enables efficient energy transfer and single‐particle visualization, while the straightforward synthesis provides versatile access to bright ...
Amin El Jarroudi Hammou, Juliette Lavainne, Rohit Mangalwedhekar, Jyothis Devasia, Laurent Cognet, Sébastien Lecommandoux, Colin Bonduelle, Chloé Grazon   +7 more
wiley   +2 more sources