Results 71 to 80 of about 1,402,473 (233)

The Role of Hemodynamic Support in High-risk Percutaneous Coronary Intervention

open access: yesUS Cardiology Review, 2020
Patients with advanced age, complex coronary anatomy, and multiple comorbidities are often unsuitable for surgical revascularization. In this setting, hemodynamic support devices are used as an adjunct to percutaneous coronary intervention to maintain ...
Charles Simonton   +4 more
doaj   +1 more source

MN•CS•IO System: Cross‐Species Study for HBB Function in High‐Altitude Hypoxia Adaptation

open access: yesAdvanced Science, EarlyView.
We developed an integrative mesh‐nanorod sorting, chitosan nanoparticle delivery, and intraosseous injection (MN•CS•IO) system to investigate HBB in high‐altitude hypoxia adaptation. Transplanting Tibetan animals' HBB‐modified Lin‐ cells into mice achieved 95.59% transfection efficiency and 8.15% HBB expression. High‐altitude HBB recipients upregulated
Wenqiao Hui   +18 more
wiley   +1 more source

Oxygen supersaturated fluid using fine micro/nanobubbles

open access: yesInternational Journal of Nanomedicine, 2014
Noriaki Matsuki,1 Takuji Ishikawa,2 Shingo Ichiba,3 Naoki Shiba,3 Yoshihito Ujike,3 Takami Yamaguchi4 1Department of Biomedical Engineering, Graduate School of Engineering, Okayama University of Science, Okayama, 2Department of Bioengineering and ...
Matsuki N   +5 more
doaj  

EphB1 Receptor Blockade Augments Morphine Antinociception via Inhibiting GRK2‐Mediated µ‐Opioid Receptor Internalization

open access: yesAdvanced Science, EarlyView.
Administration of opioids activates ephrinB2‐EphB1 receptor signaling. Activated EphB1 receptors induce GRK2‐mediated phosphorylation of MOR at Ser375, which initiates the internalization of MOR and reduces opioid antinociception at the behavioral level. ABSTRACT Opioids are the primary treatment for severe pain in clinical practice.
Bo Peng   +7 more
wiley   +1 more source

A Novel Highly Efficient Device for Growing Micro-Aerophilic Microorganisms

open access: yesFrontiers in Microbiology, 2019
This work describes a novel, simple and cost-effective culture system, named the Micro-Oxygenated Culture Device (MOCD), designed to grow microorganisms under particularly challenging oxygenation conditions.
Maxime Fuduche   +4 more
doaj   +1 more source

DataSheet_1_NADPH-Oxidase Derived Hydrogen Peroxide and Irs2b Facilitate Re-oxygenation-Induced Catch-Up Growth in Zebrafish Embryo.pdf

open access: yes, 2022
Oxygen deprivation induces multiple changes at the cellular and organismal levels, and its re-supply also brings another special physiological status.
Futa Hishima (12984440)   +10 more
core   +1 more source

Mechanism‐Informed Language Modeling and Oxygenated 3D Screening Identify Berberine–Enzalutamide Synergy in Prostate Cancer Models

open access: yesAdvanced Science, EarlyView.
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo   +15 more
wiley   +1 more source

Fossil bubble structure related to microbial activity coeval with the middle Ediacaran Oceanic Oxygenation Event in the Tandilia System

open access: yesLatin American Journal of Sedimentology and Basin Analysis, 2022
The well-preserved limestone succession, Loma Negra Formation (~40 m), in the Tandilia System was deposited in a shallow carbonate ramp under low energy conditions.
Maria Julia Arrouy   +4 more
doaj  

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

open access: yesAdvanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao   +7 more
wiley   +1 more source

Are pyranoanthocyanins involved in sensory effect in red wines?

open access: yesBIO Web of Conferences, 2016
During the wine-making process and ageing, the formation of various groups of pyranoanthocyanins leads to enhance and to stabilize the red wine colour. Although their chemical properties and their formation kinetics have been well-described, data about ...
Quaglieri Cindy   +4 more
doaj   +1 more source

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