Results 51 to 60 of about 18,915 (244)

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

Advanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng, Changyu Liu, Qin Xia, Arndt F. Schilling, Jiawei Jiang, Renpeng Peng, Zixing Shu, Tian Ma, Danni Luo, Yaoyu Zhang, Yibo Fan, Xuyuan Zhang, Song Li, Kai Wang, Wentao Ke, Yuan Xiong, Yuanli Zhu, Fangzhi Mou, Jun Xiao, Hao Zhu   +19 more
wiley   +1 more source

Variation of Oxygenation Conditions on a Hydrocarbonoclastic Microbial Community Reveals Alcanivorax and Cycloclasticus Ecotypes

Frontiers in Microbiology, 2017
Deciphering the ecology of marine obligate hydrocarbonoclastic bacteria (MOHCB) is of crucial importance for understanding their success in occupying distinct niches in hydrocarbon-contaminated marine environments after oil spills.
Fanny Terrisse, Cristiana Cravo-Laureau, Cyril Noël, Christine Cagnon, Alex J. Dumbrell, Terry J. McGenity, Robert Duran   +6 more
doaj   +1 more source

Arterial Blood‐Mediated Deep‐Tissue Photoacoustic Oximetry

Advanced Science, EarlyView.
The arterial prior method (APM+) for photoacoustic oximetry is introduced, which leverages the high arterial blood oxygenation to calibrate the fluence at the artery and estimate the oxygenation of the surrounding tissue, thus circumventing the spectral coloring problem. APM+’s accuracy and consistency are shown in a series of phantom and in vivo human
Karteekeya Sastry, Junhao Zhu, Joshua Olick‐Gibson, Li Lin, Lei Li, Jigmi Basumatary, Yang Zhang, Lihong V. Wang   +7 more
wiley   +1 more source

Overcoming the Catalytic Bucket Effect in Pt‐based High‐Entropy Nanocages Through Interface Defect and Strain Engineering

Advanced Science, EarlyView.
PtPdNiCuMnAu HENCs exhibit a remarkable half‐wave potential (E1/2) of 0.925 V vs. RHE. The catalyst displays exceptional electrochemical stability, with only a 4 mV negative shift in E1/2 and a mere 5.6% loss in MA after 10, 000 accelerated durability test cycles.
Qian Liu, Haoran Kang, Yiou Liu, Xiaowei Zhang, Xu Chen, Faming Gao   +5 more
wiley   +1 more source

Oxygen supersaturated fluid using fine micro/nanobubbles

International Journal of Nanomedicine, 2014
Noriaki Matsuki,1 Takuji Ishikawa,2 Shingo Ichiba,3 Naoki Shiba,3 Yoshihito Ujike,3 Takami Yamaguchi4 1Department of Biomedical Engineering, Graduate School of Engineering, Okayama University of Science, Okayama, 2Department of Bioengineering and ...
Matsuki N, Ishikawa T, Ichiba S, Shiba N, Ujike Y, Yamaguchi T   +5 more
doaj  

A Novel Highly Efficient Device for Growing Micro-Aerophilic Microorganisms

Frontiers in Microbiology, 2019
This work describes a novel, simple and cost-effective culture system, named the Micro-Oxygenated Culture Device (MOCD), designed to grow microorganisms under particularly challenging oxygenation conditions.
Maxime Fuduche, Sylvain Davidson, Céline Boileau, Long-Fei Wu, Yannick Combet-Blanc   +4 more
doaj   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

Fossil bubble structure related to microbial activity coeval with the middle Ediacaran Oceanic Oxygenation Event in the Tandilia System

Latin American Journal of Sedimentology and Basin Analysis, 2022
The well-preserved limestone succession, Loma Negra Formation (~40 m), in the Tandilia System was deposited in a shallow carbonate ramp under low energy conditions.
Maria Julia Arrouy, Lucía Gómez-Peral, Victoria Penzo, Camila Ferreyra, Daniel G. Poiré   +4 more
doaj  

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source

Are pyranoanthocyanins involved in sensory effect in red wines?

BIO Web of Conferences, 2016
During the wine-making process and ageing, the formation of various groups of pyranoanthocyanins leads to enhance and to stabilize the red wine colour. Although their chemical properties and their formation kinetics have been well-described, data about ...
Quaglieri Cindy, Iachetti Gianmarco, Jourdes Michael, Waffo-Teguo Pierre, Teissedre Pierre-Louis   +4 more
doaj   +1 more source