Results 131 to 140 of about 24,159 (244)

Craniofacial Dysmorphology Associated With Phelan–McDermid Syndrome Using Three‐Dimensional Morphometrics

Clinical Genetics, EarlyView.
Using 3D morphometrics quantifies genetic contribution to head and face development. ABSTRACT Phelan–McDermid syndrome (PMS) frequently presents with distinctive facial features, although a typical facial phenotype for this condition has not been well characterized.
Katherine Weisensee, Sara M. Sarasua, Lior Rennert, Curtis Rogers, Katy Phelan, Kara Powder, Luigi Boccuto   +6 more
wiley   +1 more source

Lagged climate‐driven range shifts at species' leading, but not trailing, range edges revealed by multispecies seed addition experiment

Ecography, EarlyView.
Climate change is causing many species' ranges to shift upslope to higher elevations as species track their climatic requirements. However, many species have not shifted in pace with recent warming (i.e. ‘range stasis'), possibly due to demographic lags or microclimatic buffering.
Katie J. A. Goodwin, Nathalie I. Chardon, Kavya Pradhan, Janneke Hille Ris Lambers, Amy L. Angert   +4 more
wiley   +1 more source

Cyp3a4-Mediated in vitro Metabolism and in vivo Disposition of Lorlatinib in Rats

Drug Design, Development and Therapy
Cong Xie,1,2,* Tongshu Guan,1,2,* Jin Huang,1,2 Jiayu Chen,1,2 Yilei Li,1,2 Ping Zheng1,2 1Clinical Pharmacy Center, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China; 2Department of Pharmacy, Nanfang ...
Xie C, Guan T, Huang J, Chen J, Li Y, Zheng P   +5 more
doaj  

Pharmacokinetics and aqueous humor penetration of levofloxacin 1.5% and moxifloxacin 0.5% in patients undergoing cataract surgery

Clinical Ophthalmology, 2016
Frank A Bucci Jr, Ines Teuma Nguimfack, Angel T Fluet Bucci Laser Vision Institute, Wilkes-Barre, PA, USA Purpose: The objective of this study was to compare the pharmacokinetics of levofloxacin 1.5% and moxifloxacin hydrochloride 0.5% ophthalmic ...
Bucci Jr FA, Nguimfack IT, Fluet AT
doaj  

Influence of Ultrasonic‐Assisted Milling on Surface Integrity and Fatigue Strength of a Low Alloy Steel

Fatigue &Fracture of Engineering Materials &Structures, EarlyView.
ABSTRACT The milling process significantly influences the surface integrity of metallic components through machining induced near‐surface residual stresses. Modern hybrid machining processes, such as ultrasonic‐assisted milling (USAM), offer the potential to induce beneficial near‐surface compressive residual stresses compared to the near‐surface ...
Lorenz Engelking, Mauro Madia, Dirk Schröpfer, Julius Kruse, Romeo Saliwan Neumann, Thomas Kannengießer   +5 more
wiley   +1 more source

Molecular Imaging and Pharmacokinetic Analysis of Carbon-11 Labeled Antisense Oligonucleotide LY2181308 in Cancer Patients

Theranostics, 2011
Antisense oligonucleotides (ASOs) have potential as anti-cancer agents by specifically modulating genes involved in tumorigenesis. However, little is known about ASO biodistribution and tissue pharmacokinetics (PKs) in humans, including whether ...
Azeem Saleem, Julian C. Matthews, Malcolm Ranson, Sophie Callies, Valérie André, Michael Lahn, Claire Dickinson, Christian Prenant, Gavin Brown, Adam McMahon, Denis C. Talbot, Terry Jones, Patricia M. Price
doaj  

A Comparison of Endodontic Microbiomes Associated With Symptomatic and Asymptomatic Apical Periodontitis by Next‐Generation Sequencing

International Endodontic Journal, EarlyView.
ABSTRACT Aim This cross‐sectional study aimed to compare the endodontic microbiome assessed from root canals of teeth associated with either symptomatic or asymptomatic apical periodontitis and analysed by 16S rDNA gene sequencing. Methodology 60 teeth presenting clinical and radiographic signs of symptomatic or asymptomatic apical periodontitis (n ...
David Donnermeyer, Edgar Schäfer, Daniel Hagenfeld, Benjamin Ehmke, Karola Prior, Dag Harmsen, Madgalena Ibing, Sebastian Bürklein, Thomas Gerhard Wolf, Johannes Matern   +9 more
wiley   +1 more source

Mind-matter interactions and their reproducibility [PDF]

, 2019
Dechamps, Moritz
core   +2 more sources

Beyond AIC: An Interpretive Descriptive Qualitative Study of Youth Experiences and Perceptions of Living With Type 2 Diabetes

Journal of Advanced Nursing, EarlyView.
ABSTRACT Objective To generate an in‐depth understanding of the perceptions and experiences of individuals with youth‐onset type 2 diabetes (T2D) to inform knowledge translation initiatives and clinical care. Design Interpretive descriptive qualitative study. Methods Individuals were eligible to participate if they received a T2D diagnosis on or before
Mandy M. Archibald, Allison Dart, Brandy Wicklow, Katherine J. Pundyk, Seth D. Marks, Elizabeth A. C. Sellers   +5 more
wiley   +1 more source

Nurse Leaders' Perceptions of Development of Their Own Interpersonal Communication Competence: A Qualitative Descriptive Study in Social and Healthcare Organisations

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim(s) To describe nurse leaders' perceptions of factors related to the development of their own interpersonal communication competence. Design Qualitative descriptive study. Methods Individual semi–structured interviews were conducted with 21 nurse leaders in three wellbeing service counties in Finland.
Petra Kämäräinen, Leena Mikkola, Anu Nurmeksela, Tarja Kvist   +3 more
wiley   +1 more source