Results 141 to 150 of about 24,159 (244)

Coniferyl aldehyde from the phenylpropanoid pathway targets pyruvate kinase in Dactylobotrys graminicola to confer sheath rot resistance in hulless barley

Journal of Integrative Plant Biology, EarlyView.
Hulless barley resists the newly identified sheath rot disease caused by the necrotrophic fungal pathogen Dactylobotrys graminicola by releasing coniferyl aldehyde, a natural compound that disrupts energy production in the fungus. ABSTRACT Dactylobotrys graminicola (Dgr), a necrotrophic fungal pathogen, has recently been identified as the causative ...
Haowen Zheng, Liyifan Chen, Jianguo Wei, Yuandi Xu, Rangrang Chen, Yu Li, Yan Liu, Jiahui Yan, Lu Hou, Yiliang Chen, Zhensheng Kang, Haifeng Zhang, Qiang Yao   +12 more
wiley   +1 more source

Do the redefined EUCAST susceptibility categories warrant adjustment of paediatric antibiotic dosages? Pragmatic physiologically based pharmacokinetic modelling of four commonly used agents. [PDF]

J Antimicrob Chemother
de Hoop-Sommen MA, Freriksen JJM, van der Heijden JEM, Jacobs J, Oosterlaan Y, Staring CM, van der Zeeuw SL, van der Zanden TM, van der Bruggen JT, Quaak MSW, Vermont C, Wolfs TFW, Brüggemann RJM, Greupink R, de Wildt SN.   +14 more
europepmc   +1 more source

Purposeful Management and the Public Good: Relationships, Tensions, and Consequences

Journal of Management Studies, EarlyView.
Abstract Traditional management practices have long prioritized organizational performance and financial growth, primarily serving shareholder interests. However, escalating societal and environmental challenges – such as climate change, human rights violations, the dismantling of democratic institutions, and public health crises – raise questions ...
Gideon D. Markman, Christopher Wickert, Kristina Potočnik, Hannes Leroy, Daniel Muzio, Elena Dalpiaz   +5 more
wiley   +1 more source

Randomized study of the efficacy, safety, and pharmacokinetics of SPR720 for the treatment of Mycobacterium avium complex pulmonary disease. [PDF]

Sci Rep
Ussery XT, Bhatt N, Critchley IA, Wong SL, Pottage JC, Melnick D, Hamed KA.   +6 more
europepmc   +1 more source

Sleep Deprivation in Mice: Looking Beyond the Slow Wave Rebound

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep is a fundamental process supporting the dynamic regulation of neural function. Emerging methods have proposed that the aperiodic components of brain signals (such as the spectral slope, spectral intercept, and spectral knee), in addition to entropy‐based measures, offer robust empirical markers of neural states.
Tárek Zoltán Magyar, Orsolya Szalárdy, Róbert Bódizs   +2 more
wiley   +1 more source

The Selective Estrogen Receptor Degrader ZN-c5 Has Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models. [PDF]

Mol Cancer Ther
Ma J, Hegde S, Sergeeva M, Chakraborty B, Wardell SE, McDonnell DP, Huang PQ, Bunker KD, Doñate F, Lackner MR, Samatar AA.   +10 more
europepmc   +1 more source

Microbiological, Clinical, and Pharmacokinetic/Pharmacodynamic Data to Support EUCAST Aztreonam-Avibactam Minimum Inhibitory Concentration Susceptibility Breakpoints Against Enterobacterales. [PDF]

Infect Dis Ther
Raber SR, Xie R, Rogers H, Soto E, Arhin FF, Stone GG, Leister-Tebbe H, Chow JW.   +7 more
europepmc   +1 more source

Organ‐specific terpenoid responses in Tanacetum vulgare are chemotype‐dependent

Plant Biology, EarlyView.
Common tansy varieties defend differently: some boost root chemicals against soil pests, while others release stronger leaf scents against aphids. Abstract Specialized metabolites such as terpenoids are known to mediate plant defence mechanisms. However, how terpenoid diversity governs inducible chemistry across organs remains poorly understood.
H. Newrzella, R. Heinen, C. M. Villasante, I. Zimmer, B. Weber, P. Kary, G. Gerl, A. Neuhaus, A. Sigalas, L. Ojeda‐Prieto, J. B. Winkler, W. W. Weisser, J.‐P. Schnitzler   +12 more
wiley   +1 more source

Bone Induction as a Function of Size and Chemical Composition of Calcium Phosphate Granules in Osteogrow-C Evaluated in Animal Models: A 1-Year Follow-Up. [PDF]

Biomater Res
Stokovic N, Ivanjko N, Milesevic M, Muzina K, Pecin M, Maticic D, Vukicevic S.   +6 more
europepmc   +1 more source

Experimental biofilm models for pharmacokinetic and pharmacodynamic investigations: bridging in vitro, ex vivo and in vivo systems. [PDF]

J Antimicrob Chemother
Supparitsch S, Zeitlinger M.
europepmc   +1 more source