Evidentiary Standards for Newly Approved Antibiotics for Uncomplicated Urinary Tract Infections. [PDF]
Rodriguez-Monguio R +2 more
europepmc +1 more source
Atomic‐scale copper clusters anchored on π‐extended poly(heptazine imide) enable selective, sacrificial‐agent‐free solar conversion of carbon dioxide (CO2) to ethanol. The catalyst promotes interfacial charge separation and stabilizes key carbon‐carbon coupling intermediates, providing a molecularly defined platform for direct C2 fuel synthesis under ...
Muhammad Zaeem Azam Khan +12 more
wiley +1 more source
Bioengineered extracellular vesicles escape lysosomal degradation and deliver Tet-PKM2 for macrophage immunometabolic reprogramming and periodontitis treatment. [PDF]
Zhang WJ +14 more
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The mechanism for ionic conductivity enhancement induced by BH4− substitution in argyrodites has been elucidated. BH4− substitution at the 4a/4d sites enhances Li+ transport by uniformizing cage sizes and providing continuous inter‐cage hopping pathways, while dynamic coupling between BH4− reorientation and Li+ transport motion further promotes long ...
Yoonju Shin +9 more
wiley +1 more source
Comparative pharmacokinetics of trimethoprim-sulfadiazine and trimethoprim-sulfamethoxazole in dogs. [PDF]
Ekstrand C +6 more
europepmc +1 more source
Structural insights into urocanate reductase using room‐temperature X‐ray crystallography
The active‐site dynamics of the microbial enzyme urocanate reductase were revealed by room‐temperature X‐ray crystallography.Urocanate reductase (UrdA) is a bacterial enzyme that converts urocanic acid to imidazole propionate. Its catalytic residue Arg411 undergoes a large conformational change in the substrate‐bound versus product‐bound states.
Swati Aggarwal +4 more
wiley +1 more source
Safety and Efficacy of HexaBody-DR5/DR5 in Malignant Solid Tumors: Phase 1/2a Results and Translational Insights Into Observed Hepatotoxicity. [PDF]
Overdijk MB +19 more
europepmc +1 more source
Read the free Plain Language Summary for this article on the Journal blog. Abstract Plants can respond to herbivore attack by inducing resistance traits that affect subsequent herbivore performance and behaviour. Here, we investigate how such induced responses in Solidago altissima L.
André Kessler, Katja Poveda
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Interferon stimulatory DNA activates the DNA damage signaling through ATM and DNA-PK sensing. [PDF]
Kemiha S +7 more
europepmc +1 more source
Pharmacokinetic-pharmacodynamic modeling to evaluate the relative impact of immune response and meropenem on bacterial killing <i>in vivo</i>. [PDF]
Saporta R +9 more
europepmc +1 more source

