Results 41 to 50 of about 990,521 (271)

PK-resistant PrP species are responsible for acute synaptotoxicity.

, 2018
(A) PrP immuno-depletion selectively depleted ~77 ± 12% of PrPC (dNBH) from cNBH and ~77 ± 9% total PrP species and 96 ± 4% of PK-resistant PrP (dM1000) from cM1000 relative to the normal rabbit serum (NRS) controls.
Blaine Roberts (2250916), Paul Anthony Adlard (5590958), Matteo Senesi (5614373), Abu Mohammed Taufiqual Islam (5616035), Shannon Sarros (5616038), Steven John Collins (5616041), Victoria Lawson (585860), Feng Chen (25347), David Isaac Finkelstein (5614367), Harold Arthur Coleman (5614370), Simote Totauhelotu Foliaki (5614364), Victoria Lewis (331841)   +11 more
core   +1 more source

Correcting Apparent Priming Bias Unveils Fertilizer Nitrogen‐Risk Archetypes of Surplus and Depletion Across Asian Rice Systems

Advanced Science, EarlyView.
Correcting the apparent priming effect resolves systematic biases in Asian rice fertilizer nitrogen accounting. Net soil retention drops below 7%, while 48% of fertilizer escapes, inflicting US$98.53 billion in annual reactive‐nitrogen damages. High‐resolution mapping uncovers N‐risk archetypes across 42% of the rice area, delivering a spatially ...
Xiuyun Liu, Siyuan Cai, Longlong Xia, Jagdish K. Ladha, Xiaoyuan Yan, Xu Zhao   +5 more
wiley   +1 more source

Improving Light Outcoupling and Addressing Measurement Specifics in Perovskite Light‐Emitting Diodes with Light Management Foils

Advanced Photonics Research
Near‐infrared perovskite light‐emitting diodes (PeLEDs), with four perovskite (PK) layer thicknesses and optional micro‐textured light management (LM) foil, are fabricated to evaluate their effects on light outcoupling efficiency.
Milan Kovačič, Marko Jošt, Janez Krč, Marko Topič   +3 more
doaj   +1 more source

Chronic Methamphetamine Effects on Brain Structure and Function in Rats. [PDF]

PLoS ONE, 2016
Methamphetamine (MA) addiction is a growing epidemic worldwide. Chronic MA use has been shown to lead to neurotoxicity in rodents and humans. Magnetic resonance imaging (MRI) studies in MA users have shown enlarged striatal volumes and positron emission ...
Panayotis K Thanos, Ronald Kim, Foteini Delis, Mala Ananth, George Chachati, Mark J Rocco, Ihssan Masad, Jose A Muniz, Samuel C Grant, Mark S Gold, Jean Lud Cadet, Nora D Volkow   +11 more
doaj   +1 more source

Twisted MoS2 Bilayers as Functional Elements in Memtransistors: Hysteresis, Optical Signatures, and Photocurrent Kinetics

Advanced Electronic Materials, EarlyView.
ABSTRACT Layered 2D materials are considered as promising for memristive applications due to their ultimate vertical scalability compared to conventional semiconductor films and pronounced hysteresis properties. Bias‐resolved Raman and Photoluminescence mapping is used to quantify strain from phonon shifts and carrier density from the exciton‐trion ...
Vladislav Kurtash, Ilya Eliseyev, Valery Davydov, Heiko O. Jacobs, Jörg Pezoldt   +4 more
wiley   +1 more source

Capacitive versus Faradaic Microelectrodes for Extracellular Stimulation: A Fully Coupled FEM–Hodgkin–Huxley Study of Thresholds and Current Redistribution

Advanced Electronic Materials, EarlyView.
A fully coupled FEM–HH model shows that ideally capacitive microelectrodes can achieve lower charge‐density thresholds than Faradaic contacts under current‐controlled stimulation. The advantage stems from the dynamics of surface current density on capacitive interfaces, which redirects current beneath adherent neurons.
Aleksandar Opančar, Eric Daniel Głowacki, Vedran Đerek   +2 more
wiley   +1 more source

Pharmacokinetic/pharmacodynamic analysis of teicoplanin in patients with MRSA infections

Clinical Pharmacology: Advances and Applications, 2016
Kazuaki Matsumoto,1 Erika Watanabe,1 Naoko Kanazawa,1 Tomohide Fukamizu,1 Akari Shigemi,1 Yuta Yokoyama,1,2 Kazuro Ikawa,2 Norifumi Morikawa,2 Yasuo Takeda1 1Department of Clinical Pharmacy and Pharmacology, Graduate School of Medical and Dental Sciences,
Matsumoto K, Watanabe E, Kanazawa N, Fukamizu T, Shigemi A, Yokoyama Y, Ikawa K, Morikawa N, Takeda Y   +8 more
doaj  

On mechanical and morphological investigations of tungsten inert gas welded SS 304 thin pipe joints

Measurement + Control, 2020
Tungsten inert gas welding is one of the established joining processes for stainless steel. But hitherto very little has been reported on induced residual stresses in circular thin pipe joints during tungsten inert gas welding of SS 304.
Hitesh Arora, Rupinder Singh, Gurinder Singh Brar   +2 more
doaj   +1 more source

When Biology Meets Medicine: A Perspective on Foundation Models

Advanced Intelligent Discovery, EarlyView.
Artificial intelligence, and foundation models in particular, are transforming life sciences and medicine. This perspective reviews biological and medical foundation models across scales, highlighting key challenges in data availability, model evaluation, and architectural design.
Kunying Niu, Yuxing Wang, Limin Zou, Jing Huang   +3 more
wiley   +1 more source

How does the Kids SIPsmartER program impact the sugar‐sweetened beverage intake of students: An investigation beyond total treatment effect in randomized controlled trial

American Journal of Agricultural Economics, EarlyView.
Abstract This study develops and empirically estimates a structural framework to decompose the causal pathways of multilevel behavioral interventions targeting adolescent health behaviors. We apply this framework to the Kids SIPsmartER (KSS) program, a 6‐month, school‐based intervention evaluated through a clustered randomized controlled trial in rural
Naveen Abedin, Wen You, Annie Reid, Kathleen Porter, Brittany Kirkpatrick, Jamie Zoellner   +5 more
wiley   +1 more source