Results 11 to 20 of about 231,929 (260)
Background. Micro-RNAs are fundamental agents of post-transcriptional control of gene expression. In recent years many works have appeared on the possible role of micro-RNAs in rheumatoid arthritis (RA).
A. Gnylorybov +5 more
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Novel micro‐RNAs and intermediates of micro‐RNA biogenesis from moss [PDF]
SummaryMicro‐RNAs (miRNAs) are one class of small non‐coding RNAs that have important regulatory roles in higher plants. Much less is known about their prevalence and function in lower land plants. Previously we cloned 100 non‐structural small RNAs from the moss Physcomitrella patens but could annotate only 11 as miRNAs.
Mali, Talmor-Neiman +4 more
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Biochemical and Molecular Alterations of Micro RNA 125b and Micro RNA 489-3p as diseases biomarkers in Hepatitis C Virus (HCV) [PDF]
Hepatitis C virus caused acute and chronic hepatitis. Micro RNA could be used as disease biomarkers. This study was look into Micro RNA125b, Micro RNA 489-3p, and biochemical analysis as a diagnostic for HCV.
amira Elweshahi +3 more
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miR-22-3p relieves the osteoarthritis by targeting to inflammasome in vivo and in vitro
Osteoarthritis (OA) is a common degenerative disease of the joints. It has become one of the main diseases that cause the disability of the elderly in the world, and it has a severe impact on the quality of life of patients.
Lu Bai +4 more
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MTUS1 (microtubule-associated tumor suppressor 1) has been identified that can function as a tumor suppressor gene in many malignant tumors. However, the function and mechanisms underlying the regulation of MTUS1 are unclear.
Yuanyuan Gu +12 more
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Micro(RNA) Managing by mTORC1 [PDF]
In this issue of Molecular Cell, Ye et al. (2015) demonstrate that mTORC1 globally regulates miRNA biogenesis under nutrient-rich conditions via the E3 ubiquitin ligase Mdm2, which promotes Drosha degradation.
Jewell, Jenna L +2 more
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Diagnostic possibilities of using micro-RNA for kidney transplantation
Allogeneic kidney transplantation is the optimal approach for the treatment of patients with terminal stage of chronic kidney disease. Moreover, post-transplant monitoring and optimization of immunosuppressive therapy with early non-invasive molecular ...
I. A. Pirozhkov +4 more
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Micro-RNA in lung transplant recipients: the prospects of clinical application
This review summarizes the current literature devoted to the analysis of diagnostic role of biomarkers in rejection of the transplanted lung. Numerous researches have focused on small non-coding RNAs (micro-RNA) that regulate gene expression and affect ...
D. A. Velikiy +4 more
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Micro‐RNAs and breast cancer [PDF]
Micro‐RNAs (miRs) are a recently described class of genes, encoding small non‐coding RNA molecules, which primarily act by down‐regulating the translation of target mRNAs. miRs are involved in a range of normal physiological processes, notably differentiation and cell type determination.
John, Le Quesne, Carlos, Caldas
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Alternative Polyadenylation Results in mRNA Transcript Instability in Gestational Diabetes Mellitus
Yujing He,1 Na Wu1,2 1Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of China; 2Department of Medical Service Quality, Shengjing Hospital of China Medical University, Shenyang, People’s Republic ...
He Y, Wu N
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