Results 11 to 20 of about 231,929 (260)

The role of regulatory micro-RNAs in inflammatory processes and production of tumor necrosis factor-alpha in patients with rheumatoid arthritis

open access: yesBolʹ, Sustavy, Pozvonočnik, 2023
Background. Micro-RNAs are fundamental agents of post-transcriptional control of gene expression. In recent years many works have appeared on the possible role of micro-RNAs in rheumatoid arthritis (RA).
A. Gnylorybov   +5 more
doaj   +1 more source

Novel micro‐RNAs and intermediates of micro‐RNA biogenesis from moss [PDF]

open access: yesThe Plant Journal, 2006
SummaryMicro‐RNAs (miRNAs) are one class of small non‐coding RNAs that have important regulatory roles in higher plants. Much less is known about their prevalence and function in lower land plants. Previously we cloned 100 non‐structural small RNAs from the moss Physcomitrella patens but could annotate only 11 as miRNAs.
Mali, Talmor-Neiman   +4 more
openaire   +2 more sources

Biochemical and Molecular Alterations of Micro RNA 125b and Micro RNA 489-3p as diseases biomarkers in Hepatitis C Virus (HCV) [PDF]

open access: yesBenha Veterinary Medical Journal, 2023
Hepatitis C virus caused acute and chronic hepatitis. Micro RNA could be used as disease biomarkers. This study was look into Micro RNA125b, Micro RNA 489-3p, and biochemical analysis as a diagnostic for HCV.
amira Elweshahi   +3 more
doaj   +1 more source

miR-22-3p relieves the osteoarthritis by targeting to inflammasome in vivo and in vitro

open access: yesTürk Biyokimya Dergisi, 2022
Osteoarthritis (OA) is a common degenerative disease of the joints. It has become one of the main diseases that cause the disability of the elderly in the world, and it has a severe impact on the quality of life of patients.
Lu Bai   +4 more
doaj   +1 more source

Oncogenic miR-19a and miR-19b co-regulate tumor suppressor MTUS1 to promote cell proliferation and migration in lung cancer

open access: yesProtein & Cell, 2017
MTUS1 (microtubule-associated tumor suppressor 1) has been identified that can function as a tumor suppressor gene in many malignant tumors. However, the function and mechanisms underlying the regulation of MTUS1 are unclear.
Yuanyuan Gu   +12 more
doaj   +1 more source

Micro(RNA) Managing by mTORC1 [PDF]

open access: yesMolecular Cell, 2015
In this issue of Molecular Cell, Ye et al. (2015) demonstrate that mTORC1 globally regulates miRNA biogenesis under nutrient-rich conditions via the E3 ubiquitin ligase Mdm2, which promotes Drosha degradation.
Jewell, Jenna L   +2 more
openaire   +4 more sources

Diagnostic possibilities of using micro-RNA for kidney transplantation

open access: yesВестник трансплантологии и искусственных органов, 2018
Allogeneic kidney transplantation is the optimal approach for the treatment of patients with terminal stage of chronic kidney disease. Moreover, post-transplant  monitoring and optimization of immunosuppressive therapy with early non-invasive  molecular ...
I. A. Pirozhkov   +4 more
doaj   +1 more source

Micro-RNA in lung transplant recipients: the prospects of clinical application

open access: yesВестник трансплантологии и искусственных органов, 2019
This review summarizes the current literature devoted to the analysis of diagnostic role of biomarkers in rejection of the transplanted lung. Numerous researches have focused on small non-coding RNAs (micro-RNA) that regulate gene expression and affect ...
D. A. Velikiy   +4 more
doaj   +1 more source

Micro‐RNAs and breast cancer [PDF]

open access: yesMolecular Oncology, 2010
Micro‐RNAs (miRs) are a recently described class of genes, encoding small non‐coding RNA molecules, which primarily act by down‐regulating the translation of target mRNAs. miRs are involved in a range of normal physiological processes, notably differentiation and cell type determination.
John, Le Quesne, Carlos, Caldas
openaire   +2 more sources

Alternative Polyadenylation Results in mRNA Transcript Instability in Gestational Diabetes Mellitus

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2023
Yujing He,1 Na Wu1,2 1Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of China; 2Department of Medical Service Quality, Shengjing Hospital of China Medical University, Shenyang, People’s Republic ...
He Y, Wu N
doaj  

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