Results 31 to 40 of about 231,929 (260)

Effect of Cyclophosphamide on miRNA-15a expression in EBV infected transformed B cell

فصلنامه دانشگاه علوم پزشکی جهرم, 2021
Background: Despite advances in diagnosis and therapy of cancer, it is still the main cause of death worldwide. Cyclophosphamide is one of the major drugs for lymphoma treatment.
Abdolreza Sotoodeh Jahromi, Mohammad Kargar, Maliheh Moradzadeh, Farshid Kafilzadeh, Marzieh Jamalidoust   +4 more
doaj  

Differential expression of micro RNA-29 family in non-diabetic adults of diabetic and non-diabetic parents

BMC Research Notes, 2021
Objective MicroRNAs are known to regulate 60% of genes at post translational level. MicroRNAs including Micro RNA-29 family play a vital role in cellular activities and have validate role in numerous metabolic disorders inclusive of diabetes mellitus and
Uzair Abbas, Bushra Imdad, Sikander Adil Mughal, Israr Ahmed Baloch, Afshan Mehboob Khan, Durr-e-Sameen Kamran   +5 more
doaj   +1 more source

Hepatocellular Carcinoma Prediction and early Diagnosis of Hepatitis B and C viral infection using miR-122 and miR-223 in a sample of Iraqi patients.

مجلة بغداد للعلوم, 2023
Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death. Therefore, it is critical for researchers to understand molecular biology in greater depth.
Saja Khudhier Essa Al-Juboori, Shaymaa I K Al-Juboori   +1 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Micro-RNA in development [PDF]

International Journal of Drug Discovery, 2009
This article reviews the available literature on the regulation of miRNA processing that occurs within normal cells and embryonic stem cells, during development or in diseases such as cancer. Also, explains miRNA biogenesis process for which regulation occurs.
Thikekar VP, Sawant JJ, More MK, Nair VK, Athalekar P, Patil D, Kulkarni S, Gomase VS   +7 more
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Prediction of preeclampsia using a combination of serum micro RNA-210 and uterine artery Doppler ultrasound

Science Progress, 2021
The objective was to determine whether a combination of serum micro RNA-210 level and uterine artery Doppler can predict preeclampsia in pregnant women at 16–24 weeks gestation.
Ananya Trongpisutsak, Vorapong Phupong
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

STUDYING THE PREVALENCE AND NEGATIVE IMPACT OF DIFFERENT TYPES OF TOBACCO PRODUCTS ON ADOLESCENT HEALTH

Проблеми екології та медицини
Introduction. Recently, alternative forms of tobacco use, particularly electronic devices for heating tobacco (vapes), have gained significant popularity among adolescents.
D.O. Klymko
doaj   +1 more source

Micro RNA Sensing with Green Emitting Silver Nanoclusters

Molecules, 2020
Micro RNA (miR) are regulatory non-coding RNA molecules, which contain a small number of nucleotides ~18–28 nt. There are many various miR sequences found in plants and animals that perform important functions in developmental, metabolic, and disease ...
Liam E. Yourston, Alexey V. Krasnoslobodtsev   +1 more
doaj   +1 more source