Results 41 to 50 of about 44,040 (298)
Frontiers in Ecology and Evolution, 2023 Confining pressure is an important factor affecting the strength and deformation characteristics of rock mass, it is of great significance to study the mechanical and deformation characteristics of jointed rock mass under confining pressure for the ...
Lang Song +5 more
doaj +1 more source
Journal of Aeronautical MaterialsThe damage evolution and failure process of pre-corroded additive manufacturing AlSi10Mg through in-situ tensile experiments under an optical microscope and micro-scale digital image correlation（μ-DIC） were investigates .
JIANG Sheng, DU Juan, SONG Haipeng
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
, 2016 A method for detecting micro-cracks in solar cells using two dimensional matched filters was developed, derived from the electroluminescence intensity profile of typical micro-cracks. We describe the image processing steps to obtain a binary map with the
Peter Hacke +5 more
core +1 more source
Method for Detecting Micron Cracks on a Magnetic Rotor Surface Based on a Support Vector Machine
IEEE Access, 2018 Micro-scale cracks on the surface of a magnetic rotor are difficult to detect because of the formation of stains. A method that is based on computer vision and a support vector machine (SVM) that can accurately and rapidly locate micro-scale cracks are ...
Haodi Hu +4 more
doaj +1 more source
Applied Sciences, 2022 Although the material has developed micro-scale cracks, the micro-cracks stop propagating and transform into non-propagating cracks (NPCs) under fatigue limit loading.
Zhuo Zhou, Deqing Guan
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source