Results 11 to 20 of about 344,370 (242)
Neoplasia: An International Journal for Oncology Research, 2002 Activation of the insulin-like growth factor-1 receptor (IGF-11R) by IGF-1 is associated with the risk and progression of many types of cancer, although despite this it remains unclear how activated IGF-1 R contributes to cancer progression.
J.S. Oh +9 more
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Critical Care Medicine, 2005 Microarrays are simple assays that measure the relative expression levels of tens of thousands of genes. Excitement about their importance and potential contributions to biology and medicine has been intense. Nonetheless, recent insights into the limitations and pitfalls of microarrays have led to caution about data interpretation. Microarrays are very
openaire +4 more sources
Sperm associated antigen 9 (SPAG9) a promising therapeutic target of ovarian carcinoma
Tumor Biology, 2018 SPAG9 is a novel tumor associated antigen, expressed in variety of malignancies. However, its role in ovarian cancer remains unexplored. SPAG9 expression was validated in ovarian cancer cells by real time PCR and Western blot.
Nirmala Jagadish +6 more
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Transcription factor GATA6 promotes migration of human coronary artery smooth muscle cells in vitro
Frontiers in Physiology, 2022 Vascular smooth muscle cell plasticity plays a pivotal role in the pathophysiology of vascular diseases. Despite compelling evidence demonstrating the importance of transcription factor GATA6 in vascular smooth muscle, the functional role of GATA6 ...
Azra Alajbegovic +6 more
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Autoimmunity, 2020 Inhalation of crystalline silica (cSiO2) in the workplace is etiologically linked to lupus and other autoimmune diseases. Exposing lupus-prone NZBWF1 mice to respirable cSiO2 unleashes a vicious cycle of inflammation and cell death in the lung that ...
Lichchavi D. Rajasinghe +9 more
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Cancer Informatics, 2013 Background Breast tumors have been described by molecular subtypes characterized by pervasively different gene expression profiles. The subtypes are associated with different clinical parameters and origin of precursor cells.
Mads Thomassen +3 more
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Replication Study: Transcriptional amplification in tumor cells with elevated c-Myc
eLife, 2018 As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Blum et al., 2015), that described how we intended to replicate selected experiments from the paper ‘Transcriptional amplification in tumor cells with elevated c ...
L Michelle Lewis +6 more
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Plasma Cell-Free DNA Methylomics of Bipolar Disorder With and Without Rapid Cycling
Frontiers in Neuroscience, 2021 Rapid cycling (RC) burdens bipolar disorder (BD) patients further by causing more severe disability and increased suicidality. Because diagnosing RC can be challenging, RC patients are at risk of rapid decline due to delayed suitable treatment.
Ada Man-Choi Ho +9 more
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Minimum Information About a Microarray Experiment (MIAME) – Successes, Failures, Challenges
The Scientific World Journal, 2009 The Minimum Information About a Microarray Experiment (known as MIAME) guidelines describe information that needs to be provided to enable the interpretation of the results of a microarray-based experiment unambiguously.
Alvis Brazma
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Seasonal dynamics of DNA and RNA viral bioaerosol communities in a daycare center
Microbiome, 2019 Background Viruses play an important role in ecosystems, including the built environment (BE). While numerous studies have characterized bacterial and fungal microbiomes in the BE, few have focused on the viral microbiome (virome).
Aaron J. Prussin +6 more
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