Comparability of Microarray Data between Amplified and Non Amplified RNA in Colorectal Carcinoma [PDF]
Microarray analysis reaches increasing popularity during the investigation of prognostic gene clusters in oncology. The standardisation of technical procedures will be essential to compare various datasets produced by different research groups.
Brueckl, WM+10 more
core +4 more sources
Sperm associated antigen 9 (SPAG9) a promising therapeutic target of ovarian carcinoma
SPAG9 is a novel tumor associated antigen, expressed in variety of malignancies. However, its role in ovarian cancer remains unexplored. SPAG9 expression was validated in ovarian cancer cells by real time PCR and Western blot.
Nirmala Jagadish+6 more
doaj +1 more source
Inhalation of crystalline silica (cSiO2) in the workplace is etiologically linked to lupus and other autoimmune diseases. Exposing lupus-prone NZBWF1 mice to respirable cSiO2 unleashes a vicious cycle of inflammation and cell death in the lung that ...
Lichchavi D. Rajasinghe+9 more
doaj +1 more source
Epithelial–Mesenchymal Transition Participates in the Formation of Vestibular Flat Epithelium
The vestibular sensory epithelium of humans and mice may degenerate into a layer of flat cells, known as flat epithelium (FE), after a severe lesion. However, the pathogenesis of vestibular FE remains unclear.
Lu He+5 more
doaj +1 more source
Use of meat juice and blood serum with a miniaturised protein microarray assay to develop a multi-parameter IgG screening test with high sample throughput potential for slaughtering pigs [PDF]
Background Serological screening of pig herds at the abattoir is considered a potential tool to improve meat inspection procedures and herd health management.
Ehricht, Ralf+8 more
core +2 more sources
Specific discrimination of three pathogenic salmonella enterica subsp enterica serotypes using CarB-based oligonuceotide microarray [PDF]
It is important to rapidly and selectively detect and analyze pathogenic Salmonella enterica subsp. enterica in contaminated food to reduce the morbidity and mortality of Salmonella infection and to guarantee food safety.
Cha, HJ, Hwang, BH, Seo, JH, Shin, HH
core +1 more source
Microarray-based ultra-high resolution discovery of genomic deletion mutations [PDF]
BACKGROUND: Oligonucleotide microarray-based comparative genomic hybridization (CGH) offers an attractive possible route for the rapid and cost-effective genome-wide discovery of deletion mutations.
Baban, D.+8 more
core +5 more sources
Background Breast tumors have been described by molecular subtypes characterized by pervasively different gene expression profiles. The subtypes are associated with different clinical parameters and origin of precursor cells.
Mads Thomassen+3 more
doaj +1 more source
Replication Study: Transcriptional amplification in tumor cells with elevated c-Myc
As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Blum et al., 2015), that described how we intended to replicate selected experiments from the paper ‘Transcriptional amplification in tumor cells with elevated c ...
L Michelle Lewis+6 more
doaj +1 more source
Examining the uses of shared data [PDF]
Background Many initiatives and repositories exist to encourage the sharing of research data, and thousands of microarray gene expression datasets are publicly available.
Douglas Fridsma+2 more
core +3 more sources