Results 11 to 20 of about 706,799 (337)
Developmental Science, 2006 Abstract Microarrays are revolutionizing genetics by making it possible to genotype hundreds of thousands of DNA markers and to assess the expression (RNA transcripts) of all of the genes in the genome. Microarrays are slides the size of a postage stamp that contain millions of DNA sequences to which single‐stranded DNA or RNA can hybridize.
Plomin, Robert, Schalkwyk, Leonard C
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BioTechniques, 2004 New high-throughput screening technologies have led to the identification of hundreds of genes with potential roles in cancer or other diseases. For evaluation of promising candidate genes, however, in-situ analysis of high numbers of clinical tissue samples is mandatory. The tissue microarray (TMA) technology greatly facilitates such analysis. In this
Ronald Simon +2 more
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The genesis of microarrays [PDF]
Biochemistry and Molecular Biology Education, 2013 AbstractThis review provides a perspective on the initial development of microarray technologies by two independent groups in the late 1980s. © 2013 by The International Union of Biochemistry and Molecular Biology, 42(2):106–113, 2014.
Pirrung, Michael C, Southern, Edwin M
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Surface free energy and microarray deposition technology [PDF]
, 2007 Microarray techniques use a combinatorial approach to assess complex biochemical interactions. The fundamental goal is simultaneous, large-scale experimentation analogous to the automation achieved in the semiconductor industry.
Aussillous +8 more
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Comparability of Microarray Data between Amplified and Non Amplified RNA in Colorectal Carcinoma [PDF]
, 2009 Microarray analysis reaches increasing popularity during the investigation of prognostic gene clusters in oncology. The standardisation of technical procedures will be essential to compare various datasets produced by different research groups.
Brueckl, WM +10 more
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MAPPI-DAT : data management and analysis for protein-protein interaction data from the high-throughput MAPPIT cell microarray platform [PDF]
, 2017 Protein-protein interaction (PPI) studies have dramatically expanded our knowledge about cellular behaviour and development in different conditions. A multitude of high-throughput PPI techniques have been developed to achieve proteome-scale coverage for ...
De Puysseleyr, Veronic +8 more
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Microarrays for microbiologists [PDF]
Microbiology, 2001 We are witnessing a remarkable change in the scale of molecular microbiological research and we are entering an era of ‘big science’. In the past decade we have moved from a time when entire research papers were based on the sequencing of a single gene or operon to a single paper describing the sequence of a whole genome.
Sacha Lucchini +2 more
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Frontiers in Oncology, 2021 Prostate cancer incidence in young men has increased. Patients diagnosed at an earlier age are likely to have aggressive prostate cancer and treatment decisions are continuing to be weighted by patient age and life expectancy.
Shashwat Sharad +15 more
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Sperm associated antigen 9 (SPAG9) a promising therapeutic target of ovarian carcinoma
Tumor Biology, 2018 SPAG9 is a novel tumor associated antigen, expressed in variety of malignancies. However, its role in ovarian cancer remains unexplored. SPAG9 expression was validated in ovarian cancer cells by real time PCR and Western blot.
Nirmala Jagadish +6 more
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A THP-1 Cell Line-Based Exploration of Immune Responses Toward Heat-Treated BLG
Frontiers in Nutrition, 2021 Allergen recognition and processing by antigen presenting cells is essential for the sensitization step of food allergy. Macrophages and dendritic cells are both phagocytic antigen presenting cells and play important roles in innate immune responses and ...
Ying Deng +8 more
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