Results 191 to 200 of about 695,874 (306)

Genome microarray analysis of transcriptional activation in multidrug resistance yeast mutants [PDF]

open access: bronze, 2000
Joseph L. DeRisi   +6 more
openalex   +1 more source

PP2A Promotes the Symmetric Division of MUC1‐Dominant Cancer Stem‐Like Cells in Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
During the G2/M phase, mucin1 (MUC1) activates protein phosphatase 2A (PP2A), leading to reduced phosphorylation of protein kinase C ζ (PKCζ) and NUMB, which promotes symmetric division and expansion of cancer stem‐like cells (CSLCs), thereby driving tumorigenesis. Combined inhibition of the MUC1–PP2A axis using LB100/GO203 with etoposide restores PKCζ
Shengze Li   +15 more
wiley   +1 more source

Editorial: Current research on serological analyses of infectious diseases

open access: yesFrontiers in Medicine, 2023
Eric William Rogier   +4 more
doaj   +1 more source

Inferring gene-pathway associations from consolidated transcriptome datasets: an interactive gene network explorer for <i>Tetrahymena thermophila</i>. [PDF]

open access: yesNAR Genom Bioinform
Bertagna MA   +9 more
europepmc   +1 more source

SNORA74A Drives Self‐Renewal of Liver Cancer Stem Cells and Hepatocarcinogenesis Through Activation of Notch3 Signaling

open access: yesAdvanced Science, EarlyView.
Abstract Liver cancer stem cells (CSCs) account for tumor initiation, heterogeneity and therapy resistance. However, the role of small nucleolar RNAs (snoRNAs) in the regulation of liver CSCs remains largely unclear. Here, this work identifies a conserved H/ACA box snoRNA SNORA74A which is highly expressed in liver CSCs.
Ziheng Zhou   +12 more
wiley   +1 more source

Analysis of topoisomerase function in bacterial replication fork movement: Use of DNA microarrays [PDF]

open access: green, 2000
Arkady Khodursky   +6 more
openalex   +1 more source

m6A‐Mediated TMCO3 Promotes Hepatocellular Carcinoma Progression by Facilitating the Membrane Translocation and Activation of AKT

open access: yesAdvanced Science, EarlyView.
TMCO3 as a downstream target of ALKBH5 is found, which regulates its expression in an m6A‐dependent manner, and then a new phosphorylation site on TMCO3 is identified and determines the specific mechanism of TMCO3 with AKT. Moreover, the combined treatment of targeting the TMCO3 and inhibition of AKT in mice models with HCC achieves great results ...
Xinxin Li   +8 more
wiley   +1 more source

EGR1 Target Genes in Prostate Carcinoma Cells Identified by Microarray Analysis [PDF]

open access: hybrid, 2000
John Svaren   +5 more
openalex   +1 more source

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