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Microarrays for microbiologists [PDF]

Microbiology, 2001
We are witnessing a remarkable change in the scale of molecular microbiological research and we are entering an era of ‘big science’. In the past decade we have moved from a time when entire research papers were based on the sequencing of a single gene or operon to a single paper describing the sequence of a whole genome.
Sacha Lucchini, Jay C. D. Hinton, Arthur Thompson   +2 more
openaire   +3 more sources

Sperm associated antigen 9 (SPAG9) a promising therapeutic target of ovarian carcinoma

Tumor Biology, 2018
SPAG9 is a novel tumor associated antigen, expressed in variety of malignancies. However, its role in ovarian cancer remains unexplored. SPAG9 expression was validated in ovarian cancer cells by real time PCR and Western blot.
Nirmala Jagadish, Rukhsar Fatima, Aditi Sharma, Sonika Devi, Vitusha Suri, Vikash Kumar, Anil Suri   +6 more
doaj   +1 more source

TM4: a free, open-source system for microarray data management and analysis.

BioTechniques, 2003
White1, J. Li1, W. Liang1, N. Bhagabati1, J. Braisted1, M. Klapa1, T. Currier1, M. Thiagarajan1, A. Sturn1, M. Snuffin2, A. Rezantsev2, D. Popov2, A. Ryltsov2, E. Kostukovich2, I. Borisovsky2, Z. Liu3, A. Vinsavich3, V. Trush3, and J. Quackenbush1,4 1The
A. Saeed, V. Sharov, J. White, J. Li, W. Liang, N. Bhagabati, J. Braisted, M. Kłapa, T. Currier, M. Thiagarajan, A. Sturn, M. Snuffin, A. Rezantsev, D. Popov, A. Ryltsov, E. Kostukovich, I. Borisovsky, Z. Liu, A. Vinsavich, V. Trush, John Quackenbush   +20 more
semanticscholar   +1 more source

Microarraying for Mechanosensivitity [PDF]

Cell Stem Cell, 2010
In a recent issue of Science, Gilbert et al. combine biomaterial microarrays with lineage tracking to demonstrate that muscle stem cell survival is sensitive to the microenvironment's mechanical stiffness (Gilbert et al., 2010). This work enhances the breadth and depth of knowledge in stem cell mechanobiology.
openaire   +3 more sources

Transcription factor GATA6 promotes migration of human coronary artery smooth muscle cells in vitro

Frontiers in Physiology, 2022
Vascular smooth muscle cell plasticity plays a pivotal role in the pathophysiology of vascular diseases. Despite compelling evidence demonstrating the importance of transcription factor GATA6 in vascular smooth muscle, the functional role of GATA6 ...
Azra Alajbegovic, Fatima Daoud, Fatima Daoud, Neserin Ali, Katarzyna Kawka, Johan Holmberg, Sebastian Albinsson   +6 more
doaj   +1 more source

Information visualization for DNA microarray data analysis: A critical review [PDF]

, 2008
Graphical representation may provide effective means of making sense of the complexity and sheer volume of data produced by DNA microarray experiments that monitor the expression patterns of thousands of genes simultaneously.
Kuljis, J, Liu, X, Zhang, L
core   +1 more source

Omega-3 fatty acid intake suppresses induction of diverse autoantibody repertoire by crystalline silica in lupus-prone mice

Autoimmunity, 2020
Inhalation of crystalline silica (cSiO2) in the workplace is etiologically linked to lupus and other autoimmune diseases. Exposing lupus-prone NZBWF1 mice to respirable cSiO2 unleashes a vicious cycle of inflammation and cell death in the lung that ...
Lichchavi D. Rajasinghe, Quan-Zhen Li, Chengsong Zhu, Mei Yan, Preeti S. Chauhan, Kathryn A. Wierenga, Melissa A. Bates, Jack R. Harkema, Abby D. Benninghoff, James J. Pestka   +9 more
doaj   +1 more source

Gene Expression Meta-Analysis identifies Cytokine Pathways and 5q Aberrations involved in Metastasis of ERBB2 Amplified and Basal Breast Cancer

Cancer Informatics, 2013
Background Breast tumors have been described by molecular subtypes characterized by pervasively different gene expression profiles. The subtypes are associated with different clinical parameters and origin of precursor cells.
Mads Thomassen, Qihua Tan, Mark Burton, Torben A. Kruse   +3 more
doaj   +1 more source

Replication Study: Transcriptional amplification in tumor cells with elevated c-Myc

eLife, 2018
As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Blum et al., 2015), that described how we intended to replicate selected experiments from the paper ‘Transcriptional amplification in tumor cells with elevated c ...
L Michelle Lewis, Meredith C Edwards, Zachary R Meyers, C Conover Talbot Jr, Haiping Hao, David Blum, Reproducibility Project: Cancer Biology   +6 more
doaj   +1 more source

Plasma Cell-Free DNA Methylomics of Bipolar Disorder With and Without Rapid Cycling

Frontiers in Neuroscience, 2021
Rapid cycling (RC) burdens bipolar disorder (BD) patients further by causing more severe disability and increased suicidality. Because diagnosing RC can be challenging, RC patients are at risk of rapid decline due to delayed suitable treatment.
Ada Man-Choi Ho, Stacey J. Winham, Bryan M. McCauley, Marija Kundakovic, Keith D. Robertson, Zhifu Sun, Tamas Ordog, Lauren M. Webb, Mark A. Frye, Marin Veldic   +9 more
doaj   +1 more source