Results 21 to 30 of about 695,874 (306)

Dendritic cells matured with recombinant human sperm associated antigen 9 (rhSPAG9) induce CD4+, CD8+ T cells and activate NK cells: a potential candidate molecule for immunotherapy in cervical cancer

Cancer Cell International, 2021
Background Dendritic cell (DC)-based immunotherapy is capable of activating the immune system and in particular tumor-specific cytotoxic T lymphocytes (CTLs) to eradicate the tumor.
Hemavathi Dhandapani, Hascitha Jayakumar, Abirami Seetharaman, Shirley Sunder Singh, Selvaluxmy Ganeshrajah, Nirmala Jagadish, Anil Suri, Rajkumar Thangarajan, Priya Ramanathan   +8 more
doaj   +1 more source

Exploratory Study of Autoantibody Profiling in Drug‐Induced Liver Injury with an Autoimmune Phenotype

Hepatology Communications, 2020
Drug‐induced liver injury (DILI) sometimes presents with an autoimmune hepatitis‐like phenotype (AI‐DILI), and it is challenging to distinguish it from de novo autoimmune hepatitis (AIH).
Craig Lammert, Chengsong Zhu, Yun Lian, Indu Raman, George Eckert, Quan‐Zhen Li, Naga Chalasani   +6 more
doaj   +1 more source

Plasma Cell-Free DNA Methylomics of Bipolar Disorder With and Without Rapid Cycling

Frontiers in Neuroscience, 2021
Rapid cycling (RC) burdens bipolar disorder (BD) patients further by causing more severe disability and increased suicidality. Because diagnosing RC can be challenging, RC patients are at risk of rapid decline due to delayed suitable treatment.
Ada Man-Choi Ho, Stacey J. Winham, Bryan M. McCauley, Marija Kundakovic, Keith D. Robertson, Zhifu Sun, Tamas Ordog, Lauren M. Webb, Mark A. Frye, Marin Veldic   +9 more
doaj   +1 more source

Microarray Identifies a Key Carcinogenic Circular RNA 0008594 That Is Related to Non-Small-Cell Lung Cancer Development and Lymph Node Metastasis and Promotes NSCLC Progression by Regulating the miR-760-Mediated PI3K/AKT and MEK/ERK Pathways

Frontiers in Oncology, 2021
PurposeThis study aimed to explore the circular RNA (circRNA/circ) profile engaged in non-small cell lung cancer (NSCLC) development and metastasis and to investigate potentially key carcinogenic circRNAs related to NSCLC.MethodsCircRNA profiles between ...
Qiushi Wang, Chunhua Yan, Chunhua Yan, Pengfei Zhang, Guanghua Li, Ruidong Zhu, Hanbing Wang, Libo Wu, Guangquan Xu   +8 more
doaj   +1 more source

Comment: Microarrays, Empirical Bayes and the Two-Groups Model [PDF]

Statistical Science 2008, Vol. 23, No. 1, 23-28, 2008
Comment on ``Microarrays, Empirical Bayes and the Two-Groups Model'' [arXiv:0808.0572]
arxiv   +2 more sources

Insulin-Like Growth Factor-1 Inscribes a Gene Expression Profile for Angiogenic Factors and Cancer Progression in Breast Epithelial Cells

Neoplasia: An International Journal for Oncology Research, 2002
Activation of the insulin-like growth factor-1 receptor (IGF-11R) by IGF-1 is associated with the risk and progression of many types of cancer, although despite this it remains unclear how activated IGF-1 R contributes to cancer progression.
J.S. Oh, J.E. Kucab, P.R. Bushel, K. Martin, L. Bennett, J. Collins, R.P. DiAugustine, J.C. Barrett, C.A. Afshari, S.E. Dunn   +9 more
doaj   +1 more source

Age and Tumor Differentiation-Associated Gene Expression Based Analysis of Non-Familial Prostate Cancers

Frontiers in Oncology, 2021
Prostate cancer incidence in young men has increased. Patients diagnosed at an earlier age are likely to have aggressive prostate cancer and treatment decisions are continuing to be weighted by patient age and life expectancy.
Shashwat Sharad, Shashwat Sharad, Travis C. Allemang, Hua Li, Hua Li, Darryl Nousome, Darryl Nousome, Anson Tai Ku, Nichelle C. Whitlock, Adam G. Sowalsky, Jennifer Cullen, Isabell A. Sesterhenn, David G. McLeod, Shiv Srivastava, Albert Dobi, Albert Dobi   +15 more
doaj   +1 more source

Sperm associated antigen 9 (SPAG9) a promising therapeutic target of ovarian carcinoma

Tumor Biology, 2018
SPAG9 is a novel tumor associated antigen, expressed in variety of malignancies. However, its role in ovarian cancer remains unexplored. SPAG9 expression was validated in ovarian cancer cells by real time PCR and Western blot.
Nirmala Jagadish, Rukhsar Fatima, Aditi Sharma, Sonika Devi, Vitusha Suri, Vikash Kumar, Anil Suri   +6 more
doaj   +1 more source

A THP-1 Cell Line-Based Exploration of Immune Responses Toward Heat-Treated BLG

Frontiers in Nutrition, 2021
Allergen recognition and processing by antigen presenting cells is essential for the sensitization step of food allergy. Macrophages and dendritic cells are both phagocytic antigen presenting cells and play important roles in innate immune responses and ...
Ying Deng, Ying Deng, Coen Govers, Ellen ter Beest, Ellen ter Beest, Aalt-Jan van Dijk, Kasper Hettinga, Harry J. Wichers, Harry J. Wichers   +8 more
doaj   +1 more source

Identification of significant features in DNA microarray data [PDF]

WIREs Comp Stat, 2013, 5(4): 309-325, 2013
DNA microarrays are a relatively new technology that can simultaneously measure the expression level of thousands of genes. They have become an important tool for a wide variety of biological experiments. One of the most common goals of DNA microarray experiments is to identify genes associated with biological processes of interest.
arxiv   +1 more source