Results 21 to 30 of about 515,000 (271)

A THP-1 Cell Line-Based Exploration of Immune Responses Toward Heat-Treated BLG

Frontiers in Nutrition, 2021
Allergen recognition and processing by antigen presenting cells is essential for the sensitization step of food allergy. Macrophages and dendritic cells are both phagocytic antigen presenting cells and play important roles in innate immune responses and ...
Ying Deng, Ying Deng, Coen Govers, Ellen ter Beest, Ellen ter Beest, Aalt-Jan van Dijk, Kasper Hettinga, Harry J. Wichers, Harry J. Wichers   +8 more
doaj   +1 more source

The effects of mismatches on hybridization in DNA microarrays: determination of nearest neighbor parameters [PDF]

Nucleic Acid Research 37, e53 (2009), 2010
Quantifying interactions in DNA microarrays is of central importance for a better understanding of their functioning. Hybridization thermodynamics for nucleic acid strands in aqueous solution can be described by the so-called nearest-neighbor model, which estimates the hybridization free energy of a given sequence as a sum of dinucleotide terms ...
arxiv   +1 more source

Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray.

Blood, 2004
Diffuse large B-cell lymphoma (DLBCL) can be divided into prognostically important subgroups with germinal center B-cell-like (GCB), activated B-cell-like (ABC), and type 3 gene expression profiles using a cDNA microarray.
C. Hans, D. Weisenburger, T. Greiner, R. Gascoyne, J. Delabie, G. Ott, H. Müller-hermelink, E. Campo, R. Braziel, E. Jaffe, Zenggang Pan, Pedro Farinha, Lynette M. Smith, B. Falini, A. Banham, A. Rosenwald, L. Staudt, J. Connors, J. Armitage, W. Chan   +19 more
semanticscholar   +1 more source

Omega-3 fatty acid intake suppresses induction of diverse autoantibody repertoire by crystalline silica in lupus-prone mice

Autoimmunity, 2020
Inhalation of crystalline silica (cSiO2) in the workplace is etiologically linked to lupus and other autoimmune diseases. Exposing lupus-prone NZBWF1 mice to respirable cSiO2 unleashes a vicious cycle of inflammation and cell death in the lung that ...
Lichchavi D. Rajasinghe, Quan-Zhen Li, Chengsong Zhu, Mei Yan, Preeti S. Chauhan, Kathryn A. Wierenga, Melissa A. Bates, Jack R. Harkema, Abby D. Benninghoff, James J. Pestka   +9 more
doaj   +1 more source

Terminal Epitope-Dependent Branch Preference of Siglecs Toward N-Glycans

Frontiers in Molecular Biosciences, 2021
Siglecs are sialic acid–binding immunoglobulin-like lectins that play vital roles in immune cell signaling. Siglecs help the immune system distinguish between self and nonself through the recognition of glycan ligands.
Shuaishuai Wang, Congcong Chen, Minhui Guan, Minhui Guan, Minhui Guan, Ding Liu, Xiu-Feng Wan, Xiu-Feng Wan, Xiu-Feng Wan, Xiu-Feng Wan, Lei Li   +10 more
doaj   +1 more source

Java Treeview - extensible visualization of microarray data

Bioinform., 2004
Open source software encourages innovation by allowing users to extend the functionality of existing applications. Treeview is a popular application for the visualization of microarray data, but is closed-source and platform-specific, which limits both ...
A. Saldanha
semanticscholar   +1 more source

Can new immunoassay techniques improve bladder cancer diagnostics With protein biomarkers?

Frontiers in Molecular Biosciences, 2021
The search for new diagnostic tests for cancer or ways to improve existing tests is primarily driven by the desire to identify the disease as early as possible.
Yuri M. Shlyapnikov, Ekaterina A. Malakhova, Andrey Z. Vinarov, Andrey A. Zamyatnin, Andrey A. Zamyatnin, Andrey A. Zamyatnin, Elena A. Shlyapnikova   +6 more
doaj   +1 more source

Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation.

Nucleic Acids Research, 2002
There are many sources of systematic variation in cDNA microarray experiments which affect the measured gene expression levels (e.g. differences in labeling efficiency between the two fluorescent dyes).
Y. H. Yang, S. Dudoit, Percy Luu, Dave Lin, V. Peng, J. Ngai, T. Speed   +6 more
semanticscholar   +1 more source

Conceptual Design and Parametric Optimization of a New Multileveled Horsetail Structure for Bicycle Helmets

Advanced Engineering Materials, EarlyView., 2023
This study aims to explore the feasibility of using a structure inspired by the features of horsetail and human spine as the potential helmet liner, targeting at mitigation of acceleration‐induced injuries. A parametric study is conducted to investigate the effect of individual geometrical variables in the design, indicating its capability to reduce ...
Bing Leng, Dong Ruan, Shanqing Xu, Kwong Ming Tse   +3 more
wiley   +1 more source

Gene Expression Meta-Analysis identifies Cytokine Pathways and 5q Aberrations involved in Metastasis of ERBB2 Amplified and Basal Breast Cancer

Cancer Informatics, 2013
Background Breast tumors have been described by molecular subtypes characterized by pervasively different gene expression profiles. The subtypes are associated with different clinical parameters and origin of precursor cells.
Mads Thomassen, Qihua Tan, Mark Burton, Torben A. Kruse   +3 more
doaj   +1 more source