Results 21 to 30 of about 344,370 (242)

Microarray Identifies a Key Carcinogenic Circular RNA 0008594 That Is Related to Non-Small-Cell Lung Cancer Development and Lymph Node Metastasis and Promotes NSCLC Progression by Regulating the miR-760-Mediated PI3K/AKT and MEK/ERK Pathways

Frontiers in Oncology, 2021
PurposeThis study aimed to explore the circular RNA (circRNA/circ) profile engaged in non-small cell lung cancer (NSCLC) development and metastasis and to investigate potentially key carcinogenic circRNAs related to NSCLC.MethodsCircRNA profiles between ...
Qiushi Wang, Chunhua Yan, Chunhua Yan, Pengfei Zhang, Guanghua Li, Ruidong Zhu, Hanbing Wang, Libo Wu, Guangquan Xu   +8 more
doaj   +1 more source

Microarray Data Analysis: From Hypotheses to Conclusions Using Gene Expression Data

Cellular Oncology, 2004
We review several commonly used methods for the design and analysis of microarray data. To begin with, some experimental design issues are addressed.
Nicola J. Armstrong, Mark A. van de Wiel
doaj   +1 more source

Influence of the Postmortem/Storage Time of Human Corneas on the Properties of Cultured Limbal Epithelial Cells

Cells, 2022
Besides being a powerful model to study the mechanisms of corneal wound healing, tissue-engineered human corneas (hTECs) are sparking interest as suitable substitutes for grafting purposes. To ensure the histological and physiological integrity of hTECs,
Gaëtan Le-Bel, Pascale Desjardins, Christelle Gross, Sergio Cortez Ghio, Camille Couture, Lucie Germain, Sylvain L. Guérin   +6 more
doaj   +1 more source

Blood‐derived DNA methylation predictors of mortality discriminate tumor and healthy tissue in multiple organs

Molecular Oncology, 2020
Evidence has shown that certain methylation markers derived from blood can mirror corresponding methylation signatures in internal tissues. In the current study, we aimed to investigate two strong epigenetic predictors for life span, derived from blood ...
Yan Zhang, Melanie Bewerunge‐Hudler, Matthias Schick, Barbara Burwinkel, Esther Herpel, Michael Hoffmeister, Hermann Brenner   +6 more
doaj   +1 more source

An Omnibus Test for Differential Distribution Analysis of Continuous Microbiome Data

IEEE Access, 2021
The human microbiome is comprised of thousands of microbial species. These species will substantially influence the normal physiology of humans and cause numerous diseases. Microbiome data can be measured by sequencing, microarray, or other technologies.
Xiang Lin, Jie Zhang, Zhi Wei, Turki Turki   +3 more
doaj   +1 more source

Transcriptional changes in the rat brain induced by repetitive transcranial magnetic stimulation

Frontiers in Human Neuroscience, 2023
IntroductionTranscranial Magnetic Stimulation (TMS) is a noninvasive technique that uses pulsed magnetic fields to affect the physiology of the brain and central nervous system.
Marina Weiler, Kevin C. Stieger, Kavisha Shroff, Jessie P. Klein, William H. Wood, Yongqing Zhang, Prabha Chandrasekaran, Elin Lehrmann, Simonetta Camandola, Jeffrey M. Long, Mark P. Mattson, Kevin G. Becker, Peter R. Rapp   +12 more
doaj   +1 more source

Registered report: Transcriptional amplification in tumor cells with elevated c-Myc

eLife, 2015
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012.
David Blum, Haiping Hao, Michael McCarthy, Reproducibility Project: Cancer Biology   +3 more
doaj   +1 more source

Transcriptome changes associated with elongation of bovine conceptuses II: Differentially expressed transcripts in the endometrium on day 17 after insemination

Journal of Dairy Science, 2023
: The objective was to characterize endometrial transcriptome on d 17 of gestation in dairy cows according to conceptus length. Nonlactating Holstein cows (n = 48) were slaughtered 17 d after AI and the uterine horn ipsilateral to the corpus luteum (CL ...
P.M. Peixoto, J.J. Bromfield, E.S. Ribeiro, J.E.P. Santos, W.W. Thatcher, R.S. Bisinotto   +5 more
doaj   +1 more source

Analysing Microarray Data using the Multi-functional Immune Ontologiser

Journal of Integrative Bioinformatics, 2006
Gene expression microarrays are a prominent experimental tool in functional genomics allowing researchers to gain a deeper understanding of biological processes.
Khalid Sabah, Khan Mohsin, Wang Ping, Liu Xiaohui, Li Suling   +4 more
doaj   +1 more source

Crosstalk between Receptor and Non-receptor Mediated Chemical Modes of Action in Rat Livers Converges through a Dysregulated Gene Expression Network at Tumor Suppressor Tp53

Frontiers in Genetics, 2017
Chemicals, toxicants, and environmental stressors mediate their biologic effect through specific modes of action (MOAs). These encompass key molecular events that lead to changes in the expression of genes within regulatory pathways.
Karen M. Funderburk, Karen M. Funderburk, Scott S. Auerbach, Pierre R. Bushel   +3 more
doaj   +1 more source