Results 51 to 60 of about 544,008 (293)
A miniaturized, label‐free, and enzyme‐free biosensor (miR‐TFT) enables direct electrical detection of microRNA (miRNA) with single‐nucleotide specificity and a detection limit of 0.6 fM. Built on a tri‐channel In2O3/ZnO heterojunction and functionalized with bespoke peptide nucleic acid (PNA) probes, the device is robust, reusable, and compatible with
Wejdan S. Al Ghamdi+5 more
wiley +1 more source
A novel dissolving microneedle platform preserves HPV virus‐like particle (VLP) immunogenicity by maintaining structural integrity, crucial for eliciting potent immune responses. Buccal administration induces robust immune response, high neutralizing antibody titers, and durable sterile protection across oral and vaginal mucosal sites.
Hyemi Kim+12 more
wiley +1 more source
Genome-wide maps of DNA-protein interactions using a yeast ORF and intergenic microarray [PDF]
Vishwanath R. Iyer+8 more
openalex +1 more source
Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang+12 more
wiley +1 more source
Analysis of gene expression in lymphoid malignancies using the Lymphochip cDNA microarray [PDF]
Louis M. Staudt
openalex +1 more source
Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior
Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment affect cell responses in 2D and 3D systems. Strategies for integrating fibrous cues into engineered tissues are highlighted, and future directions for ...
Zan Lamberger, Gregor Lang
wiley +1 more source
Geometrically Controlled WNT Activation Drives Intestinal Morphogenesis
Crypt‐villi‐like morphogenesis can be driven and controlled via architectural patterns in colorectal cells with the use of digital light processing printing. The resulting mini tissues exhibit budding structures and functionality, as evidenced by increased mucin expression.
Nathaniel C. Burmas+3 more
wiley +1 more source
Detection of differentially expressed genes in primary tumor tissues using representational differences analysis coupled to microarray hybridization [PDF]
Scott M. Welford+6 more
openalex +1 more source