Results 41 to 50 of about 22,889,079 (421)

Y-Chromosome Genetic Analysis of Modern Polish Population

open access: yesFrontiers in Genetics, 2020
The study presents a full analysis of the Y-chromosome variability of the modern male Polish population. It is the first study of the Polish population to be conducted with such a large set of data (2,705 individuals), which includes genetic information ...
Łukasz Grochowalski   +17 more
doaj   +1 more source

Molecular Pathogenesis and Immune Evasion of Vesicular Stomatitis New Jersey Virus Inferred from Genes Expression Changes in Infected Porcine Macrophages

open access: yesPathogens, 2021
The molecular mechanisms associated with the pathogenesis of vesicular stomatitis virus (VSV) in livestock remain poorly understood. Several studies have highlighted the relevant role of macrophages in controlling the systemic dissemination of VSV during
Lauro Velazquez-Salinas   +3 more
doaj   +1 more source

Microarray analysis in cystic fibrosis [PDF]

open access: yesJournal of Cystic Fibrosis, 2004
DNA microarrays provide a versatile platform for applications including gene expression analysis and genotyping. In the case of cystic fibrosis (CF), DNA microarrays enable the measurement of gene expression levels of thousands of genes in parallel, and potentially therefore, to identify non-CFTR genes down- or up-regulated in CF, which could lead to ...
Paul Galvin   +3 more
openaire   +3 more sources

Rasch-based high-dimensionality data reduction and class prediction with applications to microarray gene expression data [PDF]

open access: yesExpert Systems with Applications, 2010;37(7):5178-5185, 2010
Class prediction is an important application of microarray gene expression data analysis. The high-dimensionality of microarray data, where number of genes (variables) is very large compared to the number of samples (obser- vations), makes the application of many prediction techniques (e.g., logistic regression, discriminant analysis) difficult.
arxiv   +1 more source

Scalable Additive Construction of Arrayed Microstructures with Encoded Properties for Bioimaging

open access: yesMicromachines, 2022
Microarrays are essential components of analytical instruments. The elements of microarrays may be imbued with additional functionalities and encodings using composite materials and structures, but traditional microfabrication methods present substantial
Matthew DiSalvo   +4 more
doaj   +1 more source

Diagnostic yield of chromosomal microarray analysis in fetuses with isolated increased nuchal translucency: a French multicenter study

open access: yesUltrasound in Obstetrics and Gynecology, 2018
To determine the frequency and nature of copy number variants (CNVs) identified by chromosomal microarray analysis (CMA) in a large cohort of fetuses with isolated increased nuchal translucency thickness (NT) ≥ 3.5 mm.
M. Egloff   +28 more
semanticscholar   +1 more source

Conceptual Design and Parametric Optimization of a New Multileveled Horsetail Structure for Bicycle Helmets

open access: yesAdvanced Engineering Materials, EarlyView., 2023
This study aims to explore the feasibility of using a structure inspired by the features of horsetail and human spine as the potential helmet liner, targeting at mitigation of acceleration‐induced injuries. A parametric study is conducted to investigate the effect of individual geometrical variables in the design, indicating its capability to reduce ...
Bing Leng   +3 more
wiley   +1 more source

Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation

open access: yesBioData Mining, 2011
Background To make sense out of gene expression profiles, such analyses must be pushed beyond the mere listing of affected genes. For example, if a group of genes persistently display similar changes in expression levels under particular experimental ...
Echeverría Pablo C   +4 more
doaj   +1 more source

Exome Chip Analysis of 14,026 Koreans Reveals Known and Newly Discovered Genetic Loci Associated with Type 2 Diabetes Mellitus [PDF]

open access: yesDiabetes & Metabolism Journal, 2021
Background Most loci associated with type 2 diabetes mellitus (T2DM) discovered to date are within noncoding regions of unknown functional significance. By contrast, exonic regions have advantages for biological interpretation.
Seong Beom Cho   +3 more
doaj   +1 more source

A statistical framework for the analysis of microarray probe-level data [PDF]

open access: yesAnnals of Applied Statistics 2007, Vol. 1, No. 2, 333-357, 2007
In microarray technology, a number of critical steps are required to convert the raw measurements into the data relied upon by biologists and clinicians. These data manipulations, referred to as preprocessing, influence the quality of the ultimate measurements and studies that rely upon them.
arxiv   +1 more source

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