Results 51 to 60 of about 89,130 (269)

Evaluation of the Tissue Microarray Technique for Immunohistochemical Analysis in Rectal Cancer

Archives of Pathology & Laboratory Medicine, 2002
Abstract Background.—Immunohistochemical staining for tumor-associated proteins is widely used for the identification of novel prognostic markers. Recently, a tissue-conserving, high-throughput technique, tissue microarray, has been introduced. This technique uses 0.6-mm tissue core biopsy specimens, 500 to 1000 of which are brought into
Eva, Fernebro, Michael, Dictor, Pär-Ola, Bendahl, Mårten, Fernö, Mef, Nilbert   +4 more
openaire   +2 more sources

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

RNA sequencing and microarray analysis are helpful techniques to detect obesity-related lncRNAs. LncRNA can alter cholesterol metabolism and can be a target for gene therapy

, 2021
Moataz Dowaidar
  +5 more sources

Triple-target microarray experiments: a novel experimental strategy

BMC Genomics, 2004
Background High-throughput, parallel gene expression analysis by means of microarray technology has become a widely used technique in recent years. There are currently two main dye-labelling strategies for microarray studies based on custom-spotted cDNA ...
Cooke Howard J, Roy Douglas, Costa Yael, Forster Thorsten, Maratou Klio   +4 more
doaj   +1 more source

Micropatterned Biphasic Printed Electrodes for High‐Fidelity on‐Skin Bioelectronics

Advanced Functional Materials, EarlyView.
Micropatterned biphasic printed electrodes achieve unprecedented skin conformity and low impedance by combining liquid‐metal droplets with microstructured 3D lattices. This scalable approach enables high‐fidelity detection of ECG, EMG, and EEG signals, including alpha rhythms from the forehead, with long‐term comfort and stability.
Manuel Reis Carneiro, Telmo Lopes, André F. Silva, Carmel Majidi, Mahmoud Tavakoli   +4 more
wiley   +1 more source

A Peptide Nucleic Acid‐Functionalized Heterojunction Thin Film Transistor as a Scalable and Reusable Platform for Label‐Free Detection of MicroRNA

Advanced Functional Materials, EarlyView.
A miniaturized, label‐free, and enzyme‐free biosensor (miR‐TFT) enables direct electrical detection of microRNA (miRNA) with single‐nucleotide specificity and a detection limit of 0.6 fM. Built on a tri‐channel In2O3/ZnO heterojunction and functionalized with bespoke peptide nucleic acid (PNA) probes, the device is robust, reusable, and compatible with
Wejdan S. Al Ghamdi, Jorge Romero Domínguez, Erol Hasan, Temur Maksudov, Thomas D. Anthopoulos, Dana Alsulaiman   +5 more
wiley   +1 more source

DNA microarray technology in medical diagnostics

Zdravniški Vestnik, 2007
Background: DNA microarray technology opened a completely new venue in the biomedical research. By allowing to follow the expression of thousands of genes in a single experiment (ideally we can follow the expression of the entire genome), the microarray ...
Damjana Rozman, Peter Juvan
doaj  

A Quantitative Printability Framework for Programmable Assembly of Pre‐Vascular Patterns via Laser‐Induced Forward Transfer

Advanced Healthcare Materials, EarlyView.
Laser‐Induced Forward Transfer (LIFT) is presented as a powerful micropatterning tool. An objective printability framework is developed to assess optimal printing parameter combinations. The technology is further explored for its ability to deterministically deposit microdroplets at predefined locations following CAD designs, enabling the patterning of
Cécile Bosmans, Núria Ginés Rodriguez, Ulisses Jesús Gutiérrez Hernández, David Fernandez Rivas, Marcel Karperien, Jos Malda, Liliana Moreira Teixeira, Riccardo Levato, Jeroen Leijten   +8 more
wiley   +1 more source

Robust gene selection methods using weighting schemes for microarray data analysis

BMC Bioinformatics, 2017
Background A common task in microarray data analysis is to identify informative genes that are differentially expressed between two different states. Owing to the high-dimensional nature of microarray data, identification of significant genes has been ...
Suyeon Kang, Jongwoo Song
doaj   +1 more source

Transformation Based Tri-Level Feature Selection Approach Using Wavelets and Swarm Computing for Prostate Cancer Classification

IEEE Access, 2020
Prostate Cancer is a cancer that occurs in the prostate- a small walnut shaped gland in men. This gland helps in the production of seminal fluid which is used to nourish and transport the sperm.
Sunil Kumar Prabhakar, Seong-Whan Lee
doaj   +1 more source