Results 71 to 80 of about 180,353 (259)

Light‐Fueled In‐Operando Shape Reconfiguration, Fixation, and Recovery of Magnetically Actuated Microtextured Covalent Adaptable Networks

Advanced Materials, EarlyView.
A covalent adaptable network with dynamic disulfide bonds (DS‐CAN) can rearrange its molecular topology through heating or UV irradiation. When combined with ferromagnetic particles, its photoresponsiveness at room temperature enables contactless, spatiotemporal regulation of dynamic bond exchanges during magnetomechanical actuation.
Yeomyung Yoon, Hojun Moon, Woongbi Cho, Dongwook Lee, Sohdam Jeong, Jeong Jae Wie, Chae Bin Kim   +6 more
wiley   +1 more source

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source

Assessment of SVM Reliability for Microarray Data Analysis [PDF]

, 2004
The goal of our research is to provide techniques that can assess and validate the results of SVM-based analysis of microarray data. We present preliminary results of the effect of mislabeled training samples.
Blanzieri, Enrico, Malossini, Andrea, Ng, Raymond   +2 more
core  

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Topographical Imaging Technique for Qualitative Analysis of Microarray Data [PDF]

BioTechniques, 2006
Mark W. Meisel, Anna-Lisa Paul, James Ch. Davis, Robert J. Ferl   +3 more
openaire   +4 more sources

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

Advanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin, Houxin Fan, Zhenchao Liu, Paolo Donati, Youssef Amin, Yap Wing Fen, Junbo Liang, Pier Paolo Pompa, Sailing He   +8 more
wiley   +1 more source

The CRL7FBXW8 Complex Controls the Mammary Stem Cell Compartment through Regulation of NUMB Levels

Advanced Science, EarlyView.
In breast cancer (BC), NUMB loss of function (LOF) is common and mainly driven by protein hyper‐degradation. The CRL7FBXW8 complex is the E3 ligase responsible for NUMB degradation. Inhibition of CRL7FBXW8 in NUMB‐LOF BC cells restores NUMB levels, and decreases the number of cancer stem cells and tumorigenic ability in vivo. Targeting CRL7FBXW8 offers
Simone Sabbioni, Maria Grazia Filippone, Letizia Amadori, Stefano Confalonieri, Roberta Bonfanti, Stefano Capoano, Ivan Nicola Colaluca, Stefano Freddi, Giovanni Bertalot, Giovanni Fagà, Elisa Zagarrí, Mario Varasi, Rosalind Helen Gunby, Ciro Mercurio, Salvatore Pece, Pier Paolo Di Fiore, Daniela Tosoni   +16 more
wiley   +1 more source

Accurate Transcription Factor Activity Inference to Decipher Cell Identity from Single‐Cell Transcriptomic Data with MetaTF

Advanced Science, EarlyView.
MetaTF is a new computational framework that uses single‐cell RNA sequencing (scRNA‐seq) data to infer transcription factor activity with the aim to help in deciphering cells identity starting from a heterogeneous population, and apply it to characterize mouse hematopoietic stem cells and breast cancer epithelial cells, thus identifying a novel subset ...
Yongfei Hu, Yuanyuan Zhu, Guangjue Tang, Ming Shan, Puwen Tan, Ying Yi, Xiyuan Zhang, Man Liu, Xinyu Li, Le Wu, Jia Chen, Hailong Zheng, Yan Huang, Zhuan Li, Xiaobo Li, Dong Wang   +15 more
wiley   +1 more source

Isolation Techniques of Micro/Nano‐Scaled Species for Biomedical Applications

Advanced Science, EarlyView.
Separating micro/nano‐scale bioparticles from samples is essential for disease diagnosis, prevention, and monitoring. Therefore, a comprehensive overview of the latest advanced separation technologies is provided, and characteristics and limitations based on six key performance parameters, including purity, recovery rate, throughput, resolution, size ...
Qing Lu, Zhinan Zhang, Xianting Ding
wiley   +1 more source

Imputation of truncated p-values for meta-analysis methods and its genomic application

, 2014
Microarray analysis to monitor expression activities in thousands of genes simultaneously has become routine in biomedical research during the past decade.
Ding, Ying, Lariviere, William R., Mogil, Jeffrey S., Sibille, Etienne, Tang, Shaowu, Tseng, George C.   +5 more
core   +1 more source