Results 1 to 10 of about 134,878 (263)

Staphylococcus aureus transcriptomics and single-cell sequencing approaches [PDF]

open access: yesInfection and Immunity
Staphylococcus aureus is an important cause of human infections globally and ranks among the top causes of death by bacteria. In addition, the microbe is notorious for developing resistance to antibiotics. Methicillin-resistant S.
Natalia Malachowa, Frank R. DeLeo
doaj   +2 more sources

Micro-Technologies for Assessing Microbial Dynamics in Controlled Environments

open access: yesFrontiers in Microbiology, 2022
With recent advances in microfabrication technologies, the miniaturization of traditional culturing techniques has provided ideal methods for interrogating microbial communities in a confined and finely controlled environment.
Shanna-Leigh Davidson   +6 more
doaj   +1 more source

Signaling Pathways Involved in Myocardial Ischemia–Reperfusion Injury and Cardioprotection: A Systematic Review of Transcriptomic Studies in Sus scrofa

open access: yesJournal of Cardiovascular Development and Disease, 2022
Myocardial damage in acute myocardial infarctions (AMI) is primarily the result of ischemia–reperfusion injury (IRI). Recognizing the timing of transcriptional events and their modulation by cardioprotective strategies is critical to address the ...
Hector Salazar-Gonzalez   +3 more
doaj   +1 more source

A Meta-Analysis of the Effects of High-LET Ionizing Radiations in Human Gene Expression

open access: yesLife, 2021
The use of high linear energy transfer (LET) ionizing radiation (IR) is progressively being incorporated in radiation therapy due to its precise dose localization and high relative biological effectiveness.
Theodora-Dafni Michalettou   +5 more
doaj   +1 more source

Allies or Enemies: The Role of Reactive Oxygen Species in Developmental Processes of Black Cottonwood (Populus trichocarpa)

open access: yesAntioxidants, 2020
In contrast to aboveground organs (stems and leaves), developmental events and their regulation in underground organs, such as pioneer and fine roots, are quite poorly understood.
Katarzyna Marzec-Schmidt   +5 more
doaj   +1 more source

Design of Hydrogel Silk-Based Microarrays and Molecular Beacons for Reagentless Point-of-Care Diagnostics

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
We have developed a novel microarray system based on three technologies: 1) molecular beacons designed to interact with DNA targets at room temperature (25–27°C), 2) tridimensional silk-based microarrays containing the molecular beacons immersed in the ...
Alicia Sampieri   +3 more
doaj   +1 more source

HIV-1 Nef Signaling in Intestinal Mucosa Epithelium Suggests the Existence of an Active Inter-kingdom Crosstalk Mediated by Exosomes

open access: yesFrontiers in Microbiology, 2017
The human intestinal mucosal surface represents the first defense against pathogens and regulates the immune response through the combination of epithelial cell (EC) functions and immunological factors.
Cristina Felli   +3 more
doaj   +1 more source

AMDA 2.13: A major update for automated cross-platform microarray data analysis

open access: yesBioTechniques, 2012
Microarray platforms require analytical pipelines with modules for data pre-processing including data normalization, statistical analysis for identification of differentially expressed genes, cluster analysis, and functional annotation.
Dimos Kapetis   +7 more
doaj   +1 more source

Regions of homozygosity confer a worse prognostic impact in myelodysplastic syndrome with normal karyotype

open access: yeseJHaem, 2023
Half of the myelodysplastic syndromes (MDS) have normal karyotype by conventional banding analysis. The percentage of true normal karyotype cases can be reduced by 20–30% with the complementary application of genomic microarrays.
Mar Mallo   +19 more
doaj   +1 more source

Transcriptomics in Toxicogenomics, Part I: Experimental Design, Technologies, Publicly Available Data, and Regulatory Aspects

open access: yesNanomaterials, 2020
The starting point of successful hazard assessment is the generation of unbiased and trustworthy data. Conventional toxicity testing deals with extensive observations of phenotypic endpoints in vivo and complementing in vitro models.
Pia Anneli Sofia Kinaret   +19 more
doaj   +1 more source

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