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Staphylococcus aureus transcriptomics and single-cell sequencing approaches [PDF]
Staphylococcus aureus is an important cause of human infections globally and ranks among the top causes of death by bacteria. In addition, the microbe is notorious for developing resistance to antibiotics. Methicillin-resistant S.
Natalia Malachowa, Frank R. DeLeo
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Micro-Technologies for Assessing Microbial Dynamics in Controlled Environments
With recent advances in microfabrication technologies, the miniaturization of traditional culturing techniques has provided ideal methods for interrogating microbial communities in a confined and finely controlled environment.
Shanna-Leigh Davidson +6 more
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Myocardial damage in acute myocardial infarctions (AMI) is primarily the result of ischemia–reperfusion injury (IRI). Recognizing the timing of transcriptional events and their modulation by cardioprotective strategies is critical to address the ...
Hector Salazar-Gonzalez +3 more
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A Meta-Analysis of the Effects of High-LET Ionizing Radiations in Human Gene Expression
The use of high linear energy transfer (LET) ionizing radiation (IR) is progressively being incorporated in radiation therapy due to its precise dose localization and high relative biological effectiveness.
Theodora-Dafni Michalettou +5 more
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In contrast to aboveground organs (stems and leaves), developmental events and their regulation in underground organs, such as pioneer and fine roots, are quite poorly understood.
Katarzyna Marzec-Schmidt +5 more
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We have developed a novel microarray system based on three technologies: 1) molecular beacons designed to interact with DNA targets at room temperature (25–27°C), 2) tridimensional silk-based microarrays containing the molecular beacons immersed in the ...
Alicia Sampieri +3 more
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The human intestinal mucosal surface represents the first defense against pathogens and regulates the immune response through the combination of epithelial cell (EC) functions and immunological factors.
Cristina Felli +3 more
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AMDA 2.13: A major update for automated cross-platform microarray data analysis
Microarray platforms require analytical pipelines with modules for data pre-processing including data normalization, statistical analysis for identification of differentially expressed genes, cluster analysis, and functional annotation.
Dimos Kapetis +7 more
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Half of the myelodysplastic syndromes (MDS) have normal karyotype by conventional banding analysis. The percentage of true normal karyotype cases can be reduced by 20–30% with the complementary application of genomic microarrays.
Mar Mallo +19 more
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The starting point of successful hazard assessment is the generation of unbiased and trustworthy data. Conventional toxicity testing deals with extensive observations of phenotypic endpoints in vivo and complementing in vitro models.
Pia Anneli Sofia Kinaret +19 more
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