Results 11 to 20 of about 134,878 (263)
BioTechniques, 2004 New high-throughput screening technologies have led to the identification of hundreds of genes with potential roles in cancer or other diseases. For evaluation of promising candidate genes, however, in-situ analysis of high numbers of clinical tissue samples is mandatory. The tissue microarray (TMA) technology greatly facilitates such analysis. In this
Simon R, Mirlacher M, Sauter G
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Developmental Science, 2006 Abstract Microarrays are revolutionizing genetics by making it possible to genotype hundreds of thousands of DNA markers and to assess the expression (RNA transcripts) of all of the genes in the genome. Microarrays are slides the size of a postage stamp that contain millions of DNA sequences to which single‐stranded DNA or RNA can hybridize.
Plomin, Robert, Schalkwyk, Leonard C
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Critical Care Medicine, 2005 Microarrays are simple assays that measure the relative expression levels of tens of thousands of genes. Excitement about their importance and potential contributions to biology and medicine has been intense. Nonetheless, recent insights into the limitations and pitfalls of microarrays have led to caution about data interpretation. Microarrays are very
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Microarrays for microbiologists [PDF]
Microbiology, 2001 We are witnessing a remarkable change in the scale of molecular microbiological research and we are entering an era of ‘big science’. In the past decade we have moved from a time when entire research papers were based on the sequencing of a single gene or operon to a single paper describing the sequence of a whole genome.
S, Lucchini, A, Thompson, J C D, Hinton
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Disease signatures are robust across tissues and experiments
Molecular Systems Biology, 2009 Meta‐analyses combining gene expression microarray experiments offer new insights into the molecular pathophysiology of disease not evident from individual experiments.
Joel T Dudley +3 more
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Nanomaterials, 2018 Electrochemical gas sensors are often used for identifying and quantifying redox-active analyte gases in the atmosphere. However, for amperometric sensors, the current signal is usually dependent on the electroactive surface area, which can become small ...
Ghulam Hussain +2 more
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Human Genomics, 2010 Breast cancer tumours among African Americans are usually more aggressive than those found in Caucasian populations. African-American patients with breast cancer also have higher mortality rates than Caucasian women. A better understanding of the disease
Pang Herbert +4 more
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Biosensors, 2022 A silicon lab-on-chip, for the detection of nucleic acids through the integrated PCR and hybridization microarray, was developed. The silicon lab-on-chip manufactured through bio-MEMS technology is composed of two PCR microreactors (each volume 11.2 µL ...
Giorgio Ventimiglia +3 more
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Frontiers in Immunology, 2017 Several studies have shown that erythropoietin (EPO) has neuroprotective or neuroreparative actions on diseases of the nervous system and that improves oligodendrocyte (OL) differentiation and myelination in vivo and in vitro.
Georgina Gyetvai +6 more
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Molecules, 2015 Bacterial infections represent one of the main threats to global public health. One of the major causative agents associated with high morbidity and mortality infections in hospitals worldwide is methicillin-resistant Staphylococcus aureus.
Juan Manuel J. Favela-Hernández +4 more
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