Results 91 to 100 of about 30,368 (210)

Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases

Rare Metals, EarlyView.
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan, Shengjie Xue, Junyi Yin, Shaolei Wang, Yunlei Zhou, Jieyue Liao   +5 more
wiley   +1 more source

Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice

Allergy, EarlyView.
Diet‐induced obesity increases transepidermal water loss and compromises barrier function through downregulation of tight junctions and desmosomes. During obesity, MC903 elicits a mixed Th1/2/17 immune response in the skin leading to aggravated ear swelling.
Alicia Martinek, Andrea Deinzer, Roman G. Gerlach, Jana Petzold, Lea Semmler, Christof Vorsatz, Padraic G. Fallon, Christian Schwartz   +7 more
wiley   +1 more source

Comprehensive proteomic analysis of exoproteins expressed by ERIC I, II, III and IV Paenibacillus larvae genotypes reveals a wide range of virulence factors

Virulence, 2019
American foulbrood is a quarantine disease of the honeybee Apis mellifera L. in many countries and contributes greatly to colony losses. We performed a label-free proteomics study of exoprotein fractions produced in vitro by Paenibacillus larvae ...
Tomas Erban, Justyna Zitek, Miroslava Bodrinova, Pavel Talacko, Milan Bartos, Jaroslav Hrabak   +5 more
doaj   +1 more source

Intestinal fungi contribute to development of alcoholic liver disease [PDF]

, 2017
This study was supported in part by NIH grants R01 AA020703, U01 AA021856 and by Award Number I01BX002213 from the Biomedical Laboratory Research & Development Service of the VA Office of Research and Development (to B.S.). K.H.
Ali Keshavarzian, An-Ming Yang, Bernd Schnabl, Bode, Chien-Sheng Chen, Claus Hellerbrand, Cristina Llorente, Derrick E. Fouts, Ece A. Mutlu, Fettweis, Fouts, Gordon D. Brown, Guadalupe Garcia-Tsao, Hal M. Hoffman, Jun Xu, Karen Beeri, Katrin Hochrath, Kelvin Moncera, Kim Freese, Lee, Lirui Wang, Liu, Manolito G. Torralba, Peng Chen, Peter Stärkel, Phillipp Hartmann, Ramon Bataller, Samuel B. Ho, Sena Bluemel, Serene M.L. Lee, Sokol, Tatiana Kisseleva, Tatsuo Inamine, Wagner, Wajahat Z. Mehal, Yamahiro, Yang, Yukinori Koyama   +37 more
core   +3 more sources

Single‐Cell and Multiomic Analysis Reveals Neutrophil Heterogeneity and Prognostic Value in Cervical Lesions

Cancer Science, EarlyView.
This study is the first to identify a novel neutrophil subpopulation, N4, that is closely associated with the progression of cervical cancer. Characterized by high PLAU expression and specific interactions with tumor cells, N4 neutrophils were shown to promote tumor growth and immune modulation.
Ze Wang, Liang Zhuang, Shiyi Liu, Canhui Cao, Shimin Chen, Nan Yu, Xiaoyuan Huang, Tao Zhang   +7 more
wiley   +1 more source

Chitosan nanofibers and nanoparticles for immobilization of microbial collagenase

, 2016
Účelem této práce je příprava a charakterizace nanočástic z chitosanu, které sloužily jako nosič mikrobiální kolagenázy (EC 3.4.24.3) a jejich srovnání s chitosanovými nanovlákny s kolagenázou. Morfologie a mikrostruktura nanočástic a nanovláken byly sledovány pomocí rastrovacího elektronového mikroskopu. Hydrodynamická velikost připravených nanočástic
Slováková, Marcela, Kratochvilová, Veronika, Palarčík, Jiří, Metelka, Radovan, Dvořáková, Petra, Srbová, Jana, Munzarová, Marcela, Bílková, Zuzana   +7 more
openaire   +1 more source

Calcitonin receptor-like receptor is expressed on gastrointestinal immune cells [PDF]

, 2002
Background/Aims: Pharmacological and morphological studies suggest that the gut mucosal immune system and local neuropeptide-containing neurones interact.
Göke, B., Haberberger, R., Hagner, S., Knauer, J., McGregor, G. P., Voigt, K.   +5 more
core   +1 more source

Oesophageal Epithelial Cell‐Intrinsic MHCII Regulates Food Antigen‐Dependent Eosinophilic Esophagitis in an IFNγ‐Dependent Manner

Clinical &Experimental Allergy, EarlyView.
We found that oesophageal epithelial cells upregulate MHCII expression during active EoE in humans and a mouse model. MHCII expression by EECs was governed by IFNγ‐inducible transcriptional elements. EEC‐intrinsic MHCII promoted regulatory T cell accumulation and attenuated eosinophilic oesophageal inflammation.
Eric M. Rodríguez‐López, Rachel L. Clement, Megha Lal, Yusen Zhou, Stephen D. Carro, Charles‐Antoine Assenmacher, Ravi Gautam, Jarad Beers, Amanda B. Muir, Jonathan M. Spergel, Melanie A. Ruffner, Laurence C. Eisenlohr, David A. Hill   +12 more
wiley   +1 more source

Formulation and Evaluation of Facial Serum Containing Sacha Inchi Oil (Plukenetia volubilis L.) from Indonesia as an Anti-Aging: Stability, In Vitro, and Skin Irritation Assessments

Cosmetics
Reactive oxygen species (ROS), commonly recognized as free radicals, significantly contribute to skin damage by disrupting defense and repair mechanisms, thereby accelerating the aging process.
Ira Maya, Sriwidodo Sriwidodo, Soraya Ratnawulan Mita, Cahya Khairani Kusumawulan, Norisca Aliza Putriana, Eri Amalia, Rizqa Nurul Aulia, Hadiyan Nur Sofyan, Fauzan Dzulfannazhir, Moh Hamdan Nugraha   +9 more
doaj   +1 more source

Use of Cocoa Ethanolic Extract for Treatment of Staphylococcal Infection in Rabbit-skin Model [PDF]

, 2016
In septic condition, the skin normal flora Staphylococcal spp. may trigger local and sistemic skin infection. In this study antibacterial activity of cocoa ethanolic extract (CEE) against Staphylococcus aureus and ...
Jati, M. (Misnawi), Mufida, D. C. (Diana), Perwitahati, D. (Desyana), Syamsuddin, I. K. (Ihda), Tamarizki, M. (Mekania), Tunjung-Sari, A. B. (Ariza), Wahyudi, T. (Teguh)   +6 more
core