Optimized collagenase biosynthesis (Bacillus siamensis strain Z1) and its application in collagen hydrolysate-mediated silver and zinc oxide nanoparticles synthesis and characterization with antibacterial, antioxidant and cytotoxic activities. [PDF]
Revankar AG +8 more
europepmc +1 more source
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano +11 more
wiley +1 more source
Modulation of the gut microbiota as a novel strategy to prevent anastomotic leak after colorectal surgery: Systematic scoping review. [PDF]
Helliwell JA +6 more
europepmc +1 more source
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu +15 more
wiley +1 more source
Cosmeceutical and Dermatological Potential of Shiitake Mushroom (Lentinula edodes) Extract. [PDF]
Kucuk SD +5 more
europepmc +1 more source
Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An +11 more
wiley +1 more source
GC-MS profiling, biological activities and molecular docking of total sterol extracts from Pontederia crassipes (Lake Tana, Ethiopia). [PDF]
Ben Bakrim W +7 more
europepmc +1 more source
scRNA‐seq atlas of the depressed mouse colon reveals that expansion of disease‐specific cCF1 and CTF stromal subsets disrupts epithelial homeostasis via enhanced TGF‐ß and suppressed WNT/ß‐catenin signaling, impairing stem cell function, differentiation, and intestinal barrier integrity.
Xiao‐Song Xu +8 more
wiley +1 more source
Contamination rates in umbilical cord Mesenchymal stromal cell cryopreservation: a report from Vinmec tissue bank. [PDF]
Nguyen TT +6 more
europepmc +1 more source
Ryr1 deletion reduces Ca2+ microdomains and delays global Ca2+ signaling in naïve CD4+ T cells but does not impair their activation, proliferation, or differentiation in vitro. Despite altered Ca2+ signaling, Ryr1 expression in CD4+ T cells was dispensable for their pathogenicity in murine models of intestinal inflammation.
Sogol Dostiar Tabrizi +14 more
wiley +1 more source

