Results 121 to 130 of about 16,527 (193)

Neutrophils Promote Metabolic Dysfunction‐Associated Steatotic Liver Disease Through Extracellular Vesicle‐mediated Lipid Transfer

Journal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.
Neutrophils acquire extracellular fatty acids or adipocyte‐derived lipids and store them as triglycerides, polarizing into a lipid‐laden phenotype. Lipid‐laden neutrophils are found in the peripheral blood of HFD‐fed mice and patients with MASLD. These neutrophils release extracellular vesicles enriched with triglycerides and microRNAs that deliver ...
Sanjeeb Shrestha, Soo‐Jung Jung, Seong‐Min Lim, Yu‐Bin Lee, Hyeung‐Wook Shin, Hoyul Lee, Hee‐Kyung Jin, Jae‐Sung Bae, Jae‐Han Jeon, Lai Guan Ng, Chang‐Won Hong   +10 more
wiley   +1 more source

Heterologous Expression and Characterization of Collagenases from <i>Pseudomonas chlororaphis</i> GP72. [PDF]

Biology (Basel)
Hu D, Yue S, Huang Y, Zhang S, Gong C, Deng R, Nie Y, Hu H, Wang W, Zhang X.   +9 more
europepmc   +1 more source

Time‐Restricted Feeding Prevents Cardiac Aging by Entraining Gut Microbiota Clock and Promoting Diurnal Rhythm Autophagy in Prediabetic Mice

MedComm, Volume 7, Issue 8, August 2026.
The graphical abstract image presents cardiac and intestinal changes in prediabetic and diabetic mice after time restricted feeding. ABSTRACT Time‐restricted feeding (TRF) is a promising dietary strategy for delaying metabolic aging, yet its efficacy in cardioprotection across metabolic stages remains poorly understood.
Yuying Zhou, Zhiyi Yin, Xunxi Deng, Hejun Jiang, Ying Zhou, Yongjun Wang, Liyao Fu, Shi Tai   +7 more
wiley   +1 more source

Unveiling the Bioactive Potential of the Aerial Parts of Balkan <i>Achillea clypeolata</i>: Comparison with Officinal <i>Achillea millefolium</i>. [PDF]

Pharmaceutics
Šavikin K, Jovanović A, Pirković A, Aradski AA, Živković J, Stević T, Trendafilova A.   +6 more
europepmc   +1 more source

Integrative Identification of Anti‐Photoaging Peptides From Stress‐Tolerant Microorganisms via Machine Learning and KEAP1–NRF2 Docking

Journal of Peptide Science, Volume 32, Issue 8, August 2026.
Novel short‐chain peptides targeting the KEAP1‐NRF2 axis were identified through a multimodal discovery platform combining a stress‐tolerant microbial library with machine learning and molecular docking. These peptides regulate collagen synthesis and reduce MMP1/9 levels in human fibroblasts, providing significant protection against photoaging ...
Hanui Lee, Gyeong Han Jeong, Ji Wan Choi, Taehwan Kim, Younhee Shin, Jaewon Lim, Kwang‐Woo Jung, Byung Yeoup Chung, Seung Sik Lee   +8 more
wiley   +1 more source

Dual-function thermoresponsive antibiotic-loaded hydrogel with antimicrobial and osteogenic properties for implant-related infection control. [PDF]

Bioact Mater
Dini C, da Cruz SBA, Piazza RD, Nagay BE, Marques RFC, Casarin RCV, Yang F, Feres M, Liu J, Bor B, Ervolino E, Xu L, de Avila ED, Faverani LP, Souza JGS, van den Beucken JJ, Barão VAR.   +16 more
europepmc   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, Volume 7, Issue 4, August 2026.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Perioperative changes in the microbiome during rectal cancer surgery: exploratory analysis of the National Institute for Health and Care Research (NIHR) IntAct trial. [PDF]

Br J Surg
Helliwell JA, Chilton CH, Young C, Clark EV, Wilkinson L, Fuentes Balaguer A, Bottomley D, Croft J, Corrigan N, Kirby A, Quirke P, Stocken DD, Jayne DG, Wood HM.   +13 more
europepmc   +1 more source

Production and Application of Microbial Collagenase

Current Science International
openaire   +1 more source

Menstruation is Associated With Cyclical Granulysin Peaks in Vaginal Secretions Despite Stable Expression by Cervicovaginal Immune Cells

American Journal of Reproductive Immunology, Volume 96, Issue 2, August 2026.
ABSTRACT Problem The anti‐microbial protein granulysin is present in vaginal secretions during the follicular phase of the menstrual cycle but nearly disappears during the luteal phase. The reason for this change is unknown. Methods Participants (n = 23) with regular menstrual cycles collected daily vaginal swabs for granulysin ELISAs.
Sean M. Hughes, Claire N. Levy, Dendron R. Chamberlain, Dana Varon, Britt Murphy, Katharine Schwedhelm, Juma Shafi, Jennifer M. Lund, Martin Prlic, Stephen C. De Rosa, Elizabeth Micks, Christine Johnston, Florian Hladik   +12 more
wiley   +1 more source