Results 121 to 130 of about 16,507 (195)

Unveiling the Bioactive Potential of the Aerial Parts of Balkan <i>Achillea clypeolata</i>: Comparison with Officinal <i>Achillea millefolium</i>. [PDF]

Pharmaceutics
Šavikin K, Jovanović A, Pirković A, Aradski AA, Živković J, Stević T, Trendafilova A.   +6 more
europepmc   +1 more source

A Combined Colon Organoid‐Sensory Neuron Model Reveals Epithelial Contribution to Moringin Efficacy Against Painful Inflammatory Bowel Disease

Phytotherapy Research, Volume 40, Issue 6, Page 3250-3266, June 2026.
Experimental workflow and main findings of the study. ABSTRACT Visceral pain is a major symptom of inflammatory bowel diseases (IBDs), requiring effective treatment strategies. Gut epithelium, beyond maintaining barrier integrity and microbiota homeostasis, modulates neurosensorial circuitries, influencing visceral sensitivity.
Francesco Margiotta, Elena Lucarini, Alessandra Toti, Maria Giovanna Cataldi, Clara Ciampi, Gina Rosalinda De Nicola, Lorenzo Di Cesare Mannelli, Carla Ghelardini   +7 more
wiley   +1 more source

Phytochemistry and Wound-Healing, Enzyme-Inhibitory, and Antifungal Activities of the Wild Forage Legume <i>Lotus rectus</i> L. [PDF]

Plants (Basel)
González-Vázquez M, Guerrero AQ, Zuzarte M, Salgueiro L, Alves-Silva J, Puerta R.   +5 more
europepmc   +1 more source

Magnetic Reprogramming of Macrophages Stimulates Phagocytosis of Breast Cancer Cells via a TRPC1‐STING Inflammatory Axis

Smart Medicine, Volume 5, Issue 3, June 2026.
Magnetic fields modulate macrophage‐cancer crosstalk through the STING‐TRPC1 axis. Exposure reprograms macrophages toward the anti‐cancer phenotype. Exposing cancer cells modulates cancer secretome to promote polarization and selective recruitment of M1‐tumoricidal macrophages, enhancing cancer immunogenicity.
Viresh Krishnan Sukumar, Yee Kit Tai, Jan Nikolas Iversen, Olivia Yeo, Anisha Praiselin Paul, Kwan Yu Wu, Lina Hsiu Kim Lim, Alfredo Franco‐Obregón   +7 more
wiley   +1 more source

Dual-function thermoresponsive antibiotic-loaded hydrogel with antimicrobial and osteogenic properties for implant-related infection control. [PDF]

Bioact Mater
Dini C, da Cruz SBA, Piazza RD, Nagay BE, Marques RFC, Casarin RCV, Yang F, Feres M, Liu J, Bor B, Ervolino E, Xu L, de Avila ED, Faverani LP, Souza JGS, van den Beucken JJ, Barão VAR.   +16 more
europepmc   +1 more source

Aging Impairs Macrophage Phagocytosis Through Mitochondrial ROS‐Induced Collagen Production

Aging Cell, Volume 25, Issue 6, June 2026.
Aging compromises macrophage phagocytosis via the mitochondrial ROS‐driven overproduction of intracellular collagen. This excess collagen physically binds F‐actin, paralyzing cytoskeletal turnover; however, mtROS scavenging successfully rescues actin dynamics and restores phagocytic capacity.
Yuming Wang, Xin Xu, Nuanqin Shen, Ping Han, Liuyi Wu, Yi Jin, Yiming Sun, Lanlan Xiao, Jinyou Li, Lan Wang, Yunmei Yang, Qin Zhang, Weiqian Chen, Chaohui Yu, Bowen Wu   +14 more
wiley   +1 more source

Perioperative changes in the microbiome during rectal cancer surgery: exploratory analysis of the National Institute for Health and Care Research (NIHR) IntAct trial. [PDF]

Br J Surg
Helliwell JA, Chilton CH, Young C, Clark EV, Wilkinson L, Fuentes Balaguer A, Bottomley D, Croft J, Corrigan N, Kirby A, Quirke P, Stocken DD, Jayne DG, Wood HM.   +13 more
europepmc   +1 more source

Alternative Polyadenylation Drives Runaway Pro‐Inflammatory Macrophages in Periodontitis by Enabling Escape From miRNA Repression

Cell Proliferation, Volume 59, Issue 6, June 2026.
APA‐Guided Therapeutic miRNA Selection for Periodontitis. ABSTRACT Periodontitis is a chronic inflammatory disease driven by a dysregulated host immune response, in which macrophage‐mediated inflammation shifts from protective to pathological. While monocyte‐derived macrophages (MDMs) are known to adopt a destructive, M1‐like pro‐inflammatory phenotype,
Jing Zhang, Yilong Zhao, Jiaru Deng, Shuyuan Qu, Yiyi Zhou, Qin Zhao, Yufeng Zhang   +6 more
wiley   +1 more source

Establishment of preparation methods for <i>in vitro</i> models of articular cartilage superficial zone injury. [PDF]

iScience
Zhang G, Ma N, Cao F, Fu M, Zhang B, Wen J, Guo L, Wei X.   +7 more
europepmc   +1 more source

Effects of P38 MAPK Pathway Inhibition on the Metabolism of Periodontal Ligament Fibroblasts During Inflammation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT During the development of periodontitis, osteoclast function is activated by the MAPK pathway. MMPs are able to participate in cross‐activation and self‐activation cascades, thereby modulating gene expression for osteoclast differentiation.
Cheng Qian, Yifan Gu, Feiyan Gao, Zenan Xu, Jiahui Li, Shuyu Liu, Rui He, Liangjun Zhong, Jintao Wang   +8 more
wiley   +1 more source