Results 31 to 40 of about 16,527 (193)

Purification and physico-chemical properties of Bacillus atrophaeus protease with elastolytic and fibrinogenolytic activity [PDF]

The Ukrainian Biochemical Journal
Microbial proteases, among which proteases capable of cleaving elastin, fibrin, fibrinogen, and collagen, have been a matter of interest to researchers due to their significant biotechnological potential along with low production cost.
O. V. Gudzenko, L. D. Varbanets, V. O. Chernyshenko, Y. M. Stohnii, A. M. Ostapchuk, V. O. Ivanytsia   +5 more
doaj   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Etiological findings in endodontic-periodontal infections

Biomolecules & Biomedicine, 2004
The endodontium and periodontium are closely related and disease of one may lead to secondary disease in the other. The differential diagnosis of endodontic and periodontal disease is of vital importance, so that the appropriate treatment can be done ...
Amela Lačević, Edina Vranić, Irfan Zulić   +2 more
doaj   +1 more source

Effects of a skin neuropeptide (substance p) on cutaneous microflora. [PDF]

PLoS ONE, 2013
BACKGROUND: Skin is the largest human neuroendocrine organ and hosts the second most numerous microbial population but the interaction of skin neuropeptides with the microflora has never been investigated.
Lily Mijouin, Mélanie Hillion, Yasmina Ramdani, Thomas Jaouen, Cécile Duclairoir-Poc, Marie-Laure Follet-Gueye, Elian Lati, Florent Yvergnaux, Azzedine Driouich, Luc Lefeuvre, Christine Farmer, Laurent Misery, Marc G J Feuilloley   +12 more
doaj   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

Role of Triphala in dentistry

Journal of Indian Society of Periodontology, 2014
Ayurveda is considered as the "science of life," because the ancient Indian system of health care focused views of man and his illness. India has an age-old heritage of traditional herbal medicine.
Shobha Prakash, Anup U Shelke
doaj   +1 more source

Intestinal tissues induce an SNP mutation in Pseudomonas aeruginosa that enhances its virulence: possible role in anastomotic leak. [PDF]

PLoS ONE, 2012
The most feared complication following intestinal resection is anastomotic leakage. In high risk areas (esophagus/rectum) where neoadjuvant chemoradiation is used, the incidence of anastomotic leaks remains unacceptably high (≈ 10%) even when performed ...
Andrea D Olivas, Benjamin D Shogan, Vesta Valuckaite, Alexander Zaborin, Natalya Belogortseva, Mark Musch, Folker Meyer, William L Trimble, Gary An, Jack Gilbert, Olga Zaborina, John C Alverdy   +11 more
doaj   +1 more source

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

Antioxidant and Anticollagenase Activities of Fermented Pomegranate (Punica granatum L.) Peel Juice

Cosmetics
Skin aging is driven by intrinsic factors, such as the accumulation of reactive oxygen species, and extrinsic factors, including ultraviolet (UV) radiation, which accelerate oxidative stress and extracellular matrix degradation.
Faizatun Faizatun, Nur Miftahurrohmah, Rosmawati Rosmawati   +2 more
doaj   +1 more source

Toward Nano‐Nutritional Medicine: A Remotely Activated Trans‐Vaccenic Acid‐Based Lipid Nanoparticles for Enhancing Immune Checkpoint Blockade Therapy

Advanced Science, EarlyView.
Eutectic mixtures from trans‐vaccenic acid (TVA) and stearic acid, which served as phase‐change material to encapsulate IR780, forming NIR‐responsive nanoparticles. IR780@TVA LNPs induce photothermal therapy and initiate adaptive anti‐tumor immunity.
Kang Liu, Yunlong Li, Hanmeng Liu, Peng Zhang, Mingjing Wang, Quanwei Sun, Wenshuo Yang, Zhengwei Song, Song Tan, Ye Yang, Peng She, Dengke Yin, Wei Shen   +12 more
wiley   +1 more source