Results 11 to 20 of about 16,507 (195)

Monitoring the Degradation of Collagen Hydrogels by Collagenase Clostridium histolyticum

open access: yesGels, 2020
Collagen-based hydrogels are investigated extensively in tissue engineering for their tunable physiochemical properties, biocompatibility and biodegradability.
Hon Wei Ng   +3 more
doaj   +1 more source

Collagenase Clostridium Histolyticum in the Treatment of Peyronie’s Disease: Review of a Minimally Invasive Treatment Option [PDF]

open access: yesThe World Journal of Men's Health, 2017
Peyronie’s disease (PD) is an inflammatory disorder characterized by an abnormal collagen deposition in the tunica albuginea of the penis, leading to fibrous and non-compliant plaques that can impede normal erection. Although pharmacological treatments
Andrew T Gabrielson   +2 more
doaj   +1 more source

Combined Treatments of High Hydrostatic Pressure and CO2 in Coho Salmon (Oncorhynchus kisutch): Effects on Enzyme Inactivation, Physicochemical Properties, and Microbial Shelf Life

open access: yesFoods, 2020
This study focused on applying different high hydrostatic pressure + carbon dioxide (HHP + CO2) processing conditions on refrigerated (4 °C, 25 days) farmed coho salmon (Oncorhynchus kisutch) to inactivate endogenous enzymes (protease, lipase ...
Mario Perez-Won   +7 more
doaj   +1 more source

Collagen Peptides-Minerals Complexes from the Bovine Bone by-Product to Prevent Lipids Peroxidation in Meat and Butter and to Quench Free Radicals—Influence of Proteases and of Steam Sterilisation

open access: yesApplied Sciences, 2023
Food-grade animal by-products are a source of bioactive peptides that could be used as natural antioxidant compounds. Until now, only few studies have put attention to the research of the most effective enzyme(s), to the antioxidant power of collagen ...
Laurent Aubry   +3 more
doaj   +1 more source

Gene expression of bacterial collagenolytic proteases in root caries

open access: yesJournal of Oral Microbiology, 2018
Objective: It is unknown whether bacteria play a role in the collagen matrix degradation that occurs during caries progression. Our aim was to characterize the expression level of genes involved in bacterial collagenolytic proteases in root biofilms with
Nailê Damé-Teixeira   +5 more
doaj   +1 more source

Sustained Release of Phosphates From Hydrogel Nanoparticles Suppresses Bacterial Collagenase and Biofilm Formation in vitro

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
Intestinal disease or surgical intervention results in local changes in tissue and host-derived factors triggering bacterial virulence. A key phenotype involved in impaired tissue healing is increased bacterial collagenase expression which degrades ...
Dylan Nichols   +8 more
doaj   +1 more source

Hydrolysis of the Leu-Gly bond of phenylazobenzyl-oxycarbonyl-l-Pro-l-Leu-Gly-l-Pro-D-Arg (a substrate of microbial collagenases) by treponemes isolated from the subgingival plaque of periodontitis patients [PDF]

open access: yesCurrent Microbiology, 1990
Cell extracts prepared from several oral treponemes isolated from the subgingival plaque of periodontitis patients showed high enzyme activity toward phenylazobenzyl-oxycarbonyl-l-prolyl-l-leucylglycyl-l-prolyl-d-arginine (a compound used as a substrate for microbial collagenases).
Mäkinen, Kauko K.   +3 more
openaire   +2 more sources

An overview on therapeutic potential and various applications of microbial collagenases

open access: yesJournal of Microbiology and Biotechnology Research, 2017
Collagen is the most widely distributed class of proteins in the human body. Monomers of collagen are constantly being synthesized and degraded throughout the development of a healthy individual to adulthood. The collagenase subfamily found in human matrix (metalloproteinases), are capable of hydrolyzing native collagen under physiological conditions ...
Wamik Azmi   +2 more
openaire   +1 more source

Efficacy and safety of collagenase clostridium histolyticum for Dupuytren disease nodules: a randomized controlled trial

open access: yesBMC Musculoskeletal Disorders, 2017
Background To determine the safety and efficacy of collagenase clostridium histolyticum (CCH) injection for the treatment of palmar Dupuytren disease nodules.
Bronier Costas   +5 more
doaj   +1 more source

Bone biodeterioration-The effect of marine and terrestrial depositional environments on early diagenesis and bone bacterial community.

open access: yesPLoS ONE, 2020
Bacteria play an important role in the degradation of bone material. However, much remains to be learnt about the structure of their communities in degrading bone, and how the depositional environment influences their diversity throughout the exposure ...
Anne Marie Høier Eriksen   +8 more
doaj   +1 more source

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