Results 61 to 70 of about 16,507 (195)

Underground guardians: how collagen and chitin amendments shape soil microbiome structure and function for Meloidogyne enterolobii control

Microbiome
Background The emergence of the guava root-knot nematode (Meloidogyne enterolobii) poses a significant threat to tomato yields globally. This study evaluated the impact of collagen and chitin soil amendments on soil microbial composition and function ...
Josephine M. Pasche, Roshni Sawlani, Victor Hugo Buttrós, Johan Desaeger, Karen A. Garrett, Samuel J. Martins   +5 more
doaj   +1 more source

Impact of severe periodontitis and diabetes mellitus on recurrent cardiovascular outcomes

Journal of Periodontology, EarlyView.
Abstract Background This post hoc analysis of the Periodontitis and Coronary Heart Disease study (ClinicalTrials.gov Identifier: NCT01045070) aimed to determine the association between diabetes and recurrent cardiovascular events (CVEs) in patients with cardiovascular disease (CVD) and severe periodontitis.
Stefan Reichert, Axel Schlitt, Selina Rehm, Susanne Schulz   +3 more
wiley   +1 more source

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

Med Research, EarlyView.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei, Xiaoxian Lou, Xu Su, Shubao Liu, Yanli Tong, Jie Chen, Xuerui Chen, Wenjun Mao, Hui Yu, Liangbin Lin   +9 more
wiley   +1 more source

Unlocking the Potential of Collagenases: Structures, Functions, and Emerging Therapeutic Horizons

BioDesign Research
Collagenases, a class of enzymes that are specifically responsible for collagen degradation, have garnered substantial attention because of their pivotal roles in tissue repair, remodeling, and medical interventions.
Zhen-Zhen Wang, Kang Wang, Ling-Feng Xu, Chang Su, Jin-Song Gong, Jin-Song Shi, Xu-Dong Ma, Nan Xie, Jian-Ying Qian   +8 more
doaj   +1 more source

Comprehensive proteomic analysis of exoproteins expressed by ERIC I, II, III and IV Paenibacillus larvae genotypes reveals a wide range of virulence factors

Virulence, 2019
American foulbrood is a quarantine disease of the honeybee Apis mellifera L. in many countries and contributes greatly to colony losses. We performed a label-free proteomics study of exoprotein fractions produced in vitro by Paenibacillus larvae ...
Tomas Erban, Justyna Zitek, Miroslava Bodrinova, Pavel Talacko, Milan Bartos, Jaroslav Hrabak   +5 more
doaj   +1 more source

Chitosan nanofibers and nanoparticles for immobilization of microbial collagenase

, 2016
The purpose of the paper is to describe the production and characterization of electrospun chitosan nanofibers and chitosan/TPP nanoparticles as carriers for microbial collagenase. Thie eproteolytic highly active and stable carriers have potential of advanced bioactive wound dressings.
Slováková, Marcela, Kratochvilová, Veronika, Palarčík, Jiří, Metelka, Radovan, Dvořáková, Petra, Srbová, Jana, Munzarová, Marcela, Bílková, Zuzana   +7 more
openaire   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Multi‐Omics Analysis Reveals Coordinated Adaptations in Genes, Metabolism, and Gut Microbiota Underpinning Herbivory in Lordiphosa Flies

Integrative Zoology, EarlyView.
Multi‐omics analysis reveals that herbivorous adaptation in Lordiphosa flies arises from coordinated interactions across the genome, transcriptome, and gut microbiota: genomic expansions of detoxification (e.g., cytochrome P450s) and carbohydrate metabolism gene families, transcriptomic upregulation of energy pathways like lipid oxidation and ...
Run Guo, Jianjun Gao, Caixian Zhang, Zhiheng Chang, Yanbo Sun   +4 more
wiley   +1 more source

Formulation and Evaluation of Facial Serum Containing Sacha Inchi Oil (Plukenetia volubilis L.) from Indonesia as an Anti-Aging: Stability, In Vitro, and Skin Irritation Assessments

Cosmetics
Reactive oxygen species (ROS), commonly recognized as free radicals, significantly contribute to skin damage by disrupting defense and repair mechanisms, thereby accelerating the aging process.
Ira Maya, Sriwidodo Sriwidodo, Soraya Ratnawulan Mita, Cahya Khairani Kusumawulan, Norisca Aliza Putriana, Eri Amalia, Rizqa Nurul Aulia, Hadiyan Nur Sofyan, Fauzan Dzulfannazhir, Moh Hamdan Nugraha   +9 more
doaj   +1 more source

Malaria mosquito antimicrobial defence requires immunity and detoxification gene regulation by Lola

Insect Molecular Biology, EarlyView.
Malaria mosquito antimicrobial defence requires upregulation of lola. Attenuation of lola in the midgut of Anopheles albimanus mosquitoes inhibits the upregulation of immunity genes induced by challenge. Putative target genes of the Lola transcription factor were revealed by lola attenuation, including Cecropin‐C, Draper, PPAF2, Clip‐domain serine ...
Heidi Espadas‐Álvarez, Verónica Valverde‐Garduño   +1 more
wiley   +1 more source