Results 161 to 170 of about 190,830 (306)

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

Advanced Science, EarlyView.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li, Jiaqiang Jiang, Yuping Zhou, Xinyuan Mao, Haotian Wen, Zhian Chen, Yutong Wang, Cong Huang, Yanfeng Hu   +8 more
wiley   +1 more source

Antimicrobial Multidrug Resistance and Mechanisms of Action: An Overview. [PDF]

Biomed Res Int
Temesgen AB, Shiferaw SA.
europepmc   +1 more source

Microbial Etiology, Immunological Evaluation, and Drug-Resistance Spectrum Profile of Bloodstream Infections Among Cancer Patients

Sama Jawad Al-Zuwaini, Lena Fadhil Al-Jibouri, Ali H. Al-Marzoqi, Mohammad Golbashy, Israa Adnan Ibraheam, Marwa Fadhil Alsaffar, Ali Talib Ahmed, Zainab A. Tolaifeh, Zahraa Aqeel Muslim, Mohammed Sabah Otaiwi, Israa Aqeel Mohammed Ali ALcharrakh   +10 more
openalex   +1 more source

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

Advanced Science, EarlyView.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo, Dongwon Park, Woosub Shin, Jongmin Kim   +3 more
wiley   +1 more source

Droplet microfluidics strategies for overcoming bottlenecks in antibiotics discovery. [PDF]

iScience
Barakat H, Bolton M, Cheng J, Li X.
europepmc   +1 more source

Recent advances in understanding microbial regulation of host multi-drug resistance transporters

, 2021
Sage E. Foley, Ethan B Loew, Beth A. McCormick   +2 more
openalex   +1 more source

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

From Methylomes to CRISPR Epigenetic Editing: New Paths in Antibiotic Resistance. [PDF]

Pathogens
Nass NM, Zaher KA.
europepmc   +1 more source

Clinically important microbial diversity and its antibiotic resistance pattern towards various drugs

, 2019
Gowri Manogari Boovaragamoorthy, Murugadas Anbazhagan, Prakash Piruthiviraj, Arivalagan Pugazhendhi, Smita S. Kumar, Naïf Abdullah Al-Dhabi, Abdul-Kareem Mohammed Ghilan, Mariadhas Valan Arasu, Thamaraiselvi Kaliannan   +8 more
openalex   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source