Results 161 to 170 of about 717,320 (332)

Macrophage‐Mediated Transport of Insoluble Indirubin Induces Hepatic Injury During Intestinal Inflammation

Advanced Science, EarlyView.
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu, Jingchun Shi, Heung‐Lam Mok, Cheng Lyu, Junbang Chen, Chunhua Huang, Hongyan Qin, Chengyuan Lin, Hor‐Yue Tan, Zhaoxiang Bian   +9 more
wiley   +1 more source

Polymicrobial Biofilms: Interkingdom Interactions, Resistance and Therapeutic Strategies. [PDF]

Microb Biotechnol
Nithyanand P, Boya BR, Lee JH, Lee J.
europepmc   +1 more source

The Multitarget Compound ZLY032 Achieves Treatment of Chronic Wounds

Advanced Science, EarlyView.
ZLY032, a dual free fatty acid receptor 1/peroxisome proliferator‐activated receptor δ agonist, accelerates wound healing in normal/diabetic/methicillin‐resistant Staphylococcus aureus‐infected models by promoting angiogenesis, reducing inflammation, and exhibiting antibacterial activity via argininosuccinate lyase targeting, with demonstrated efficacy
Manyu Gong, Zhiyuan Du, Tiantian Gong, Yu Wang, Chenchen Yin, Bosi Sun, Zijia Liu, Lianru Chen, Zibin Liao, Wenxin Wang, Tianjiao Zhao, Yifei Wang, Ying Dong, Kexin Wang, Mengru Ma, Weijun Li, Jiacheng Li, Haodong Li, Congcong Lin, Ying Zhang, Yu Liu, Xin Liu, Tao Ban, Hongxia Bao, Ying Zhang, Yang Zhang, Zheng Li, Lei Jiao   +27 more
wiley   +1 more source

Gut Microbiome-Based Strategies for the Control of Carbapenem-Resistant Enterobacteriaceae. [PDF]

J Microbiol Biotechnol
Lee I, Kim BS, Suk KT, Lee SS.
europepmc   +1 more source

Clinically important microbial diversity and its antibiotic resistance pattern towards various drugs

, 2019
Gowri Manogari Boovaragamoorthy, Murugadas Anbazhagan, Prakash Piruthiviraj, Arivalagan Pugazhendhi, Smita S. Kumar, Naif Abdullah Al‐Dhabi, Abdul-Kareem Mohammed Ghilan, Mariadhas Valan Arasu, Thamaraiselvi Kaliannan   +8 more
openalex   +1 more source

Inhibition of RNase to Attenuate Fungal‐Manipulated Rhizosphere Microbiome and Diseases

Advanced Science, EarlyView.
Fusarium graminearum uses its virulence effector Fg12, a fungal RNase, to manipulate the host rhizosphere microbiome and promote infection. Guanosine monophosphate (GMP) blocks Fg12's RNase activity. This reveals a key pathogen‐microbiota interaction mechanism and proposes GMP as a targeted strategy to disarm this core fungal effector, offering a ...
Bo Yang, Sen Yang, Xiaomi Wang, Yuanwei Zhang, Yao Zhao, Menghuan Tao, Jinyi Zhu, Wanxin Zhang, Yansu Wang, Kaixuan Duan, Yan Wang, Wenwu Ye, Zhenfei Guo, Yuanchao Wang   +13 more
wiley   +1 more source

Risk factors for fluoroquinolone- and macrolide-resistance among swine Campylobacter coli using multi-layered chain graphs. [PDF]

PLoS Comput Biol
Wang CA, Love WJ, Jara M, van Vliet AHM, Thakur S, Lanzas C.   +5 more
europepmc   +1 more source

Fabrication of Dual Photodynamic Enhanced Antimicrobial CDs@ZIF‐8/Polycaprolactone/Ethyl Cellulose Nanofibrous Films for Fruit Preservation

Advanced Science, EarlyView.
Carbon dots (CDs) are incorporated into ZIF‐8 to synthesize CDs@ZIF‐8 nanocomposites, which exhibit dual photodynamic enhanced antimicrobial properties. This enhancement is due to the narrow bandgap of CDs@ZIF‐8, which facilitates interfacial electronic transfer, resulting in increased reactive oxygen species. Microfluidic blow spinning is then used to
Yongrui Ti, Ziqiang Qin, Xiaohong Guo, Zheng Wu, Qi Jiang, Beihua Dong, Olaniyi Amos Fawole, Di Wu, Su Chen, Xian Li, Kunsong Chen   +10 more
wiley   +1 more source

Beyond breakpoint - reconceptualising AMR as a symptom of planetary stress. [PDF]

NPJ Antimicrob Resist
Kirchhelle C, Roberts AP.
europepmc   +1 more source

Microbial Trends and their Drug Resistance Responsible for Bloodstream Infections in a Superspeciality Transplant Hospital

Martha Zothansangi Chhangte, Niranjan Patil, Aashita Ashpalia, Raj Jatale, Shibani Ramchandran, Kirti Chadha   +5 more
openalex   +1 more source