Results 51 to 60 of about 346,542 (364)

Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: an inter-laboratory study. [PDF]

, 2019
Antimicrobial resistance (AMR) poses a threat to public health. Clinical microbiology laboratories typically rely on culturing bacteria for antimicrobial-susceptibility testing (AST).
Aller, SD, Bruchmann, S, Clark, T, Coello Pelegrin, A, Cormican, M, Diez Benavente, E, Doyle, RM, Ellington, MJ, Harris, KA, Huggett, JF, McGrath, E, Moran-Gilad, J, Motro, Y, O'Sullivan, DM, Phelan, J, Phuong Thuy Nguyen, T, Shaw, LP, Stabler, RA, van Belkum, A, van Dorp, L, Woodford, N   +20 more
core   +4 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Frequency Of Isolation Of Salmonella From Commercial Poultry Feeds And Their Anti-Microbial Resistance Profiles, Imo State, Nigeria [PDF]

, 2006
This study was conducted to determine the frequency of isolation of salmonella and their microbial resistance profiles across different commercial poultry feeds sold in Imo State, Nigeria.
Ndujihe E, G, Ogbuewu P, I, Okoli Ifeanyi, Charles   +2 more
core  

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Anti-microbial Use in Animals: How to Assess the Trade-offs [PDF]

, 2015
Antimicrobials are widely used in preventive and curative medicine in animals. Benefits from curative use are clear – it allows sick animals to be healthy with a gain in human welfare.
Acar J. F., Codex Alimentarius, Cogliani C., Davies S., Graham J. P., J. Rushton, McEwen S. A., Pagel S. W., Rushton J., Rushton J., Steinfeld H., Tisdell C., Wegener H. C.   +12 more
core   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

A review on lipid-based nanocarriers mimicking chylomicron and their potential in drug delivery and targeting infectious and cancerous diseases

AAPS Open, 2023
Infectious and cancerous diseases are tedious to manage. The problem of drug resistance is often associated with anti-microbial and anti-cancer agents and is one of the most significant challenges that restrict their activity.
Rana E. Elnady, Maha M. Amin, Mohamed Y. Zakaria   +2 more
doaj   +1 more source

Anti Microbial Resistance Profile of E. coli isolates From Tropical Free Range Chickens [PDF]

, 2005
Normal intestinal flora of humans and animals constitute enormous reservoir of resistance genes for potentially pathogenic bacteria and may serve as major indictors of selection pressure exerted by anti-microbial use in a given population.
A BI, Udedibie, K F, Chah, Okoli I, Charles, P TE, Ozoh   +3 more
core   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Statistical methods for automated drug susceptibility testing: Bayesian minimum inhibitory concentration prediction from growth curves [PDF]

Annals of Applied Statistics 2009, Vol. 3, No. 2, 710-730, 2009
Determination of the minimum inhibitory concentration (MIC) of a drug that prevents microbial growth is an important step for managing patients with infections. In this paper we present a novel probabilistic approach that accurately estimates MICs based on a panel of multiple curves reflecting features of bacterial growth.
arxiv   +1 more source