Results 61 to 70 of about 19,222,260 (230)

New Methods of Rapid Antimicrobial Susceptibility Testing: Status and Development

Xiehe Yixue Zazhi
Enhancing the speed of microbial antimicrobial susceptibility testing (AST) is an urgent requirement for effective patient treatment, rational use of antimicrobial agents, and mitigating the development of microbial resistance.
ZHANG Zhijie, LIU Yong
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Microbial fertilizers modulate tobacco growth and development through reshaping soil microbiome and metabolome

Microbiology Spectrum
To elucidate the mechanisms of microbial fertilizers in enhancing tobacco growth and quality, this greenhouse-based pot experiment conducted over 40 days post-transplanting employed integrated microbiomics and metabolomics approaches to conduct a ...
Xiaoyu Wang, Mingming Sun, Lei Tian, Mingfeng Yang, Qiang Gao, LIli Wang, Honghao Yan, Long Yang, Xin Hou, Peng Liu, Li Zhang   +10 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Ti3C2Tx (MXene) disrupts growth and development in Daphnia magna by suppressing related genes and inducing gut microbiome dysbiosis

Frontiers in Microbiology
The potential risks of Ti3C2Tx (MXene) nanomaterials to the ecological environment and human health have drawn increasing attention due to their widespread applications in the fields of biomedicine and environmental remediation.
Qianqian Xiang, Yanping Wu, Yongfang Li, Shaoxiang Li, Xuexiu Chang, Xuexiu Chang   +5 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Effects of Artificially Modified Microbial Communities on the Root Growth and Development of Tall Fescue in Nutrient-Poor Rubble Soil

Plants
The granite rubble soil produced through excavation during construction is nutrient-poor and has a simplified microbial community, making it difficult for plants to grow and increasing the challenges of ecological restoration.
Zhengyu Luo, Hongrui Han, Hui Yao, Guoru Yan, Jinxin Bai, Lihao Shi, Xiangjun Pei, Jingji Li, Qiang Li   +8 more
doaj   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source