Results 1 to 10 of about 22,180 (115)

Large-Scale Metagenome Assembly Reveals Novel Animal-Associated Microbial Genomes, Biosynthetic Gene Clusters, and Other Genetic Diversity

mSystems, 2020
Large-scale metagenome assemblies of human microbiomes have produced a vast catalogue of previously unseen microbial genomes; however, comparatively few microbial genomes derive from other vertebrates.
Nicholas D. Youngblut, Jacobo de la Cuesta-Zuluaga, Georg H. Reischer, Silke Dauser, Nathalie Schuster, Chris Walzer, Gabrielle Stalder, Andreas H. Farnleitner, Ruth E. Ley   +8 more
doaj   +3 more sources

Recovery of High Quality Metagenome-Assembled Genomes From Full-Scale Activated Sludge Microbial Communities in a Tropical Climate Using Longitudinal Metagenome Sampling

Frontiers in Microbiology, 2022
The analysis of metagenome data based on the recovery of draft genomes (so called metagenome-assembled genomes, or MAG) has assumed an increasingly central role in microbiome research in recent years.
Mindia A. S. Haryono, Ying Yu Law, Krithika Arumugam, Larry C. -W. Liew, Thi Quynh Ngoc Nguyen, Daniela I. Drautz-Moses, Stephan C. Schuster, Stephan C. Schuster, Stefan Wuertz, Stefan Wuertz, Rohan B. H. Williams   +10 more
doaj   +3 more sources

MetaSort untangles metagenome assembly by reducing microbial community complexity

Nature Communications, 2017
Currently available metagenomic data analysis relies on reference genomes. Here, the authors describe a newde novometagenomic assembly method, metaSort, that constructs bacterial genomes from metagenomic samples to reduce microbial community complexity ...
Peifeng Ji, Yanming Zhang, Jinfeng Wang, Fangqing Zhao   +3 more
doaj   +2 more sources

The chromosomal genome sequence of the sponge, Rhopaloeides odorabile Thompson, Murphy, Bergquist & Evans, 1987 (Dictyoceratida: Spongiidae) and its associated microbial metagenome sequences [version 1; peer review: 2 approved] [PDF]

Wellcome Open Research
We present a genome assembly from an individual Rhopaloeides odorabile (Porifera; Demospongiae; Dictyoceratida; Spongiidae). The genome sequence has a total length of 291.63 megabases.
Eerik Aunin, Heidi M. Luter, Victoria McKenna, Sara C. Bell, Graeme Oatley, Nicole S. Webster, Elizabeth Sinclair, Ute Hentschel, Camilla Santos, Haoyu Niu, Michael Paulini, Dirk Erpenbeck, Noah Gettle, Rebecca O’Brien   +13 more
doaj   +2 more sources

Sequential co-assembly reduces computational resources and errors in metagenome-assembled genomes

Cell Reports: Methods
Summary: Generating metagenome-assembled genomes from DNA shotgun sequencing datasets can demand considerable computational resources. Here, we describe a sequential co-assembly method that reduces the assembly of duplicate reads through successive ...
Hannah M. Lynn, Jeffrey I. Gordon
doaj   +3 more sources

Enhancing Long-Read-Based Strain-Aware Metagenome Assembly

Frontiers in Genetics, 2022
Microbial communities are usually highly diverse and often involve multiple strains from the participating species due to the rapid evolution of microorganisms.
Xiao Luo, Xiao Luo, Xiongbin Kang, Alexander Schönhuth, Alexander Schönhuth   +4 more
doaj   +1 more source

Contrasting Community Assembly Forces Drive Microbial Structural and Potential Functional Responses to Precipitation in an Incipient Soil System

Frontiers in Microbiology, 2021
Microbial communities in incipient soil systems serve as the only biotic force shaping landscape evolution. However, the underlying ecological forces shaping microbial community structure and function are inadequately understood.
Aditi Sengupta, Aditi Sengupta, Till H. M. Volkmann, Robert E. Danczak, James C. Stegen, Katerina Dontsova, Nate Abramson, Aaron S. Bugaj, Michael J. Volk, Katarena A. Matos, Antonio A. Meira-Neto, Albert Barberán, Julia W. Neilson, Raina M. Maier, Jon Chorover, Peter A. Troch, Laura K. Meredith   +16 more
doaj   +1 more source

MetaBAT, an efficient tool for accurately reconstructing single genomes from complex microbial communities [PDF]

PeerJ, 2015
Grouping large genomic fragments assembled from shotgun metagenomic sequences to deconvolute complex microbial communities, or metagenome binning, enables the study of individual organisms and their interactions.
Dongwan D. Kang, Jeff Froula, Rob Egan, Zhong Wang   +3 more
doaj   +2 more sources

MetaBAT 2: an adaptive binning algorithm for robust and efficient genome reconstruction from metagenome assemblies [PDF]

PeerJ, 2019
We previously reported on MetaBAT, an automated metagenome binning software tool to reconstruct single genomes from microbial communities for subsequent analyses of uncultivated microbial species.
Dongwan D. Kang, Feng Li, Edward Kirton, Ashleigh Thomas, Rob Egan, Hong An, Zhong Wang   +6 more
doaj   +2 more sources

A review of computational tools for generating metagenome-assembled genomes from metagenomic sequencing data

Computational and Structural Biotechnology Journal, 2021
Metagenomic sequencing provides a culture-independent avenue to investigate the complex microbial communities by constructing metagenome-assembled genomes (MAGs).
Chao Yang, Debajyoti Chowdhury, Zhenmiao Zhang, William K. Cheung, Aiping Lu, Zhaoxiang Bian, Lu Zhang   +6 more
doaj   +1 more source