PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad +2 more
wiley +1 more source
Novel enhancement of stability and antimicrobial activity of beetroot pigment nanocomposites via graphene oxide and silver nanoparticles. [PDF]
Ahmed HA, El-Wahab AEA, Gad S.
europepmc +1 more source
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra +5 more
wiley +1 more source
Metagenomes enriched with <i>Virgibacillus</i> are associated with a pink paste defect in an unpasteurized blue cheese. [PDF]
Wolfe BE.
europepmc +1 more source
ABSTRACT Objective This study evaluated the effects of polishing systems, staining solutions, and aging time on the surface roughness of Computer‐aided design and computer‐aided manufacturing (CAD/CAM) and three‐dimensional (3D)‐printed permanent restorative materials. Methods Three 3D‐printed resins (VarseoSmile Crown plus (VSC), Saremco PrintCrowntec
Nilay Bayraktar +2 more
wiley +1 more source
Polyphasic <i>in vitro</i> characterization of the pigment-producing microfungus <i>Rhodotorula</i> sp. for potential application as a probiotic in mariculture. [PDF]
Ain QU +10 more
europepmc +1 more source
Genes, fish and fisheries: translating science into policy
Abstract The 2024 Annual Symposium of the Fisheries Society of the British Isles reviewed the burgeoning impact of ‘omics’ technologies on fish ecology, management and forecasting. As with life sciences more generally, major advances in speed, cost‐effectiveness and breadth of applications in ‘omics’ has had profound societal and environmental impacts.
Gary R. Carvalho
wiley +1 more source
Correction: Bioproduction, characterization, anticancer and antioxidant activities of extracellular melanin pigment produced by newly isolated microbial cell factories Streptomyces glaucescens NEAE-H. [PDF]
El-Naggar NE, El-Ewasy SM.
europepmc +1 more source
ABSTRACT Melanistic lesions, including non‐raised black areas due to proliferations of melanocytes and melanomacrophages in the dermis and epidermis, as well as raised black areas consistent with melanoma, are described in brown bullhead (BBH) Ameiurus nebulosus from three water bodies in the northeastern United States and Quebec, Canada.
Vicki S. Blazer +9 more
wiley +1 more source
Novel Raman signature evidences an unknown cyanobacterial pigment. [PDF]
Lara YJ, Lambion A, Javaux EJ.
europepmc +1 more source

