Results 21 to 30 of about 641,669 (159)

Unique Photochemistry Observed in a New Microbial Rhodopsin

open access: yesThe Journal of Physical Chemistry Letters, 2019
Light energy is first captured in animal and microbial rhodopsins by ultrafast photoisomerization, whose relaxation accompanies protein structural changes for each function.
Hideki Kandori (534378)   +4 more
core   +3 more sources

Localization and dimer stability of a newly identified microbial rhodopsin from a polar, non-motile green algae [PDF]

open access: yesBMC Research Notes, 2018
Objective The eukaryotic plasma membrane localized light-gated proton-pumping rhodopsins possesses great optogenetic applications for repolarization (silencing) of the neuronal activity simply by light illumination.
Peeyush Ranjan, Suneel Kateriya
doaj   +2 more sources

Solid-state NMR of the retinal protonated Schiff base in microbial rhodopsins

open access: yesMagnetic Resonance Letters
Rhodopsin is a seven-helical transmembrane protein with a retinal chromophore covalently bound to a conserved lysine in helix G via a retinal protonated Schiff base (RPSB). Microbial rhodopsins absorb light through chromophore and play a fundamental role
Sari Kumagai, Izuru Kawamura
doaj   +2 more sources

Unexpected microbial rhodopsin dynamics in sync with phytoplankton blooms

open access: yesNature Communications
The surface ocean is the largest sunlit environment on Earth where marine microalgae are known as the main drivers of global productivity. However, rhodopsin phototrophs are actually the most abundant metabolic group, suggesting a major role in the ...
Laura Gómez-Consarnau   +9 more
doaj   +2 more sources

Investigating the Origin of Automatic Rhodopsin Modeling Outliers Using the Microbial Gloeobacter Rhodopsin as Testbed

open access: yesThe Journal of Physical Chemistry B
International audienceThe Automatic Rhodopsin Modeling (ARM) approach is a computational workflow devised for the automatic build up of hybrid quantum mechanics/molecular mechanics (QM/MM) models of wild-type rhodopsins and mutants, with the purpose of ...
D’ascenzi, Jacopo   +4 more
core   +4 more sources

Imaging Voltage with Microbial Rhodopsins [PDF]

open access: yesFrontiers in Molecular Biosciences, 2021
Membrane potential is the critical parameter that reflects the excitability of a neuron, and it is usually measured by electrophysiological recordings with electrodes. However, this is an invasive approach that is constrained by the problems of lacking spatial resolution and genetic specificity.
Xiao Min Zhang   +3 more
openaire   +3 more sources

Untersuchungen zur Phosphorylierung von Rhodopsin und deren Einfluss auf die Arrestin-Rhodopsin-Bindung [PDF]

open access: yes, 2021
Die phosphorylierungsabhängige Bindung von Arrestin an G-Protein-gekoppelte Rezeptoren (GPCRs) ist ein weit verbreiteter Mechanismus, um aktive Rezeptoren zu inhibieren. Für die Bindung von Arrestin an lichtaktiviertes, phosphoryliertes Rhodopsin (pRho),
Vogt, Vivien 1989-, Vogt, Vivien
core   +1 more source

All-optical closed-loop voltage clamp for precise control of muscles and neurons in live animals

open access: yesNature Communications, 2023
Optogenetic actuation regimes are often static, which allows perturbation, but not true control of neuronal activity. Here, the authors describe an all-optical method for bidirectional steering of membrane potential, in closed loop, in C. elegans muscles
Amelie C. F. Bergs   +15 more
doaj   +1 more source

Global abundance of microbial rhodopsins [PDF]

open access: yesThe ISME Journal, 2012
Abstract Photochemical reaction centers and rhodopsins are the only phototrophic mechanisms known to have evolved on Earth. The minimal cost of bearing a rhodopsin-based phototrophic mechanism in comparison to maintaining a photochemical reaction center suggests that rhodopsin is the more abundant of the two. We tested this hypothesis by
Omri M, Finkel   +2 more
openaire   +2 more sources

Omega Rhodopsins: A Versatile Class of Microbial Rhodopsins

open access: yesJournal of Microbiology and Biotechnology, 2020
Microbial rhodopsins are a superfamily of photoactive membrane proteins with covalently bound retinal cofactor. Isomerization of the retinal chromophore upon absorption of a photon triggers conformational changes of the protein to function as ion pumps or sensors.
Kwon, Soon-Kyeong   +2 more
openaire   +3 more sources

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