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Quantitative Microbial Risk Assessment of Pharmaceutical Products
PDA Journal of Pharmaceutical Science and Technology, 2016Monitoring of microbiological quality in the pharmaceutical industry is an important criterion that is required to justify safe product release to the drug market. Good manufacturing practice and efficient control on bioburden level of product components are critical parameters that influence the microbiological cleanliness of medicinal products ...
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The Application of Quantitative Risk Assessment to Microbial Food Safety Risks
Critical Reviews in Microbiology, 1996Regulatory programs and guidelines for the control of foodborne microbial agents have existed in the U.S. for nearly 100 years. However, increased awareness of the scope and magnitude of foodborne disease, as well as the emergence of previously unrecognized human pathogens transmitted via the foodborne route, have prompted regulatory officials to ...
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Accounting for inherent variability of growth in microbial risk assessment
International Journal of Food Microbiology, 2005Risk assessments of pathogens need to account for the growth of small number of cells under varying conditions. In order to determine the possible risks that occur when there are small numbers of cells, stochastic models of growth are needed that would capture the distribution of the number of cells over replicate trials of the same scenario or ...
H M, Marks, M E, Coleman
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Modeling Logistic Performance in Quantitative Microbial Risk Assessment
Risk Analysis, 2009In quantitative microbial risk assessment (QMRA), food safety in the food chain is modeled and simulated. In general, prevalences, concentrations, and numbers of microorganisms in media are investigated in the different steps from farm to fork.
Rijgersberg, H. +3 more
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Time‐Dose‐Response Models for Microbial Risk Assessment
Risk Analysis, 2009While microbial risk assessment (MRA) has been used for over 25 years, traditional dose‐response analysis has only predicted the overall risk of adverse consequences from exposure to a given dose. An important issue for consequence assessment from bioterrorist and other microbiological exposure is the distribution of cases over time due to the initial ...
Yin, Huang, Charles N, Haas
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Microbial Risk Assessment for Drinking Water
2005Infectious microbes can be transmitted through the drinking water supply. Recent research indicates that infection transmission dynamics influence the public health benefit of water treatment interventions, although some risk assessments currently in use do not fully account for those dynamics.
Stephen E. Chick +2 more
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Predictive Microbiology and Microbial Risk Assessment
2019Quantitative microbial modeling of foods represents a proactive approach to food quality and safety by accumulating information on bacterial responses to environmental factors and by summarizing the responses through mathematical models and in databases.
Abani K. Pradhan +2 more
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Scripta manent? Assessing microbial risk to paper heritage
Trends in Microbiology, 2010Paper, like all other cultural heritage materials, degrades over time, but conservation slows down the rate of its deterioration. There is a long history of cooperation between microbiologists and conservators of libraries and archival materials, but current approaches addressing paper deterioration need urgent reassessment to take full advantage of ...
Francesca Cappitelli +3 more
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Microbial Risk Assessment of Pathogens in Water
2012Water can transmit infectious diseases. Water can be transport vehicle. A range of pathogenic microorganisms is shed into the water cycle by infected hosts (man or animal) and transported to new hosts by the water cycle. Water can also be a niche for (opportunistic) pathogens.
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