Results 191 to 200 of about 226,686 (268)

Chronic alcohol consumption compromises gut barrier integrity and promotes endotoxemia: Implications for sepsis susceptibility in immunocompromised hosts

Animal Models and Experimental Medicine, EarlyView.
Chronic alcohol exposure disrupts intestinal barrier integrity, resulting in a leaky gut and enhanced translocation of lipopolysaccharide (LPS) and microbial products into the systemic circulation. Alcohol‐induced endotoxemia drives exaggerated pro‐inflammatory responses, mitochondrial damage, and activation of the cGAS–STING pathway, particularly in ...
Thansita Bhunyakarnjanarat, Chatsuree Suksamai, Dhammika Leshan Wannigama, Kent Doi, Wiwat Chancharoenthana, Asada Leelahavanichkul   +5 more
wiley   +1 more source

Microbiological spectrum and probability of transmission of infection from ocular tissues of enucleated eyes harvested from septicemic donors. [PDF]

World J Transplant
Dubey A, Priyanka, Soni D, Chaurasia D, Periasamy B, Jain NC, Sarkar D, Singh M, Khullar S, Kumar K, Chaturvedi P, Sharma B.   +11 more
europepmc   +1 more source

Exosome‐mediated gut–brain axis signaling in neurodegenerative diseases: Mechanisms, experimental evidence, and therapeutic perspectives—A narrative review

Animal Models and Experimental Medicine, EarlyView.
The gut–brain axis is a bidirectional communication network between the intestines and brain, mediated by gut microbiota and exosomes, that regulates neuroinflammation, protein aggregation, and neuronal health processes central to neurodegenerative diseases.
Waheeb Sami Aggad, Rakesh Ghosh, Hailah M. Almohaimeed, Zuhair M. Mohammedsaleh, Fayez M. Saleh, Amany I. Almars, S. Renuka Jyothi, Rajashree Panigrahi, Ajoy Kumer, Bikram Dhara   +9 more
wiley   +1 more source

Response to Matters Arising about the etiology of ventilator-associated pneumonia in the European POS-VAP cohort. [PDF]

Crit Care
de Kraker MEA, Jackson H, Hernandez Padilla AC, van Werkhoven CH, Francois B.   +4 more
europepmc   +1 more source

Sickle Cell Disease and Kidney Injury: Circulating Uromodulin Allows Early Tissue Specific Diagnosis and Monitoring of Treatment

American Journal of Hematology, EarlyView.
Ferras Alashkar, Robert Hable, Denise Zwanziger, Friederike Poppenborg, Raina Yamamoto, Hans Christian Reinhardt, Alexander Röth, Victor Herbst, Yara Bestmann, Marco Kai, Jürgen E. Scherberich   +10 more
wiley   +1 more source

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

Pulmonary Actinomycosis: A Hidden Threat with Clinical Impact. [PDF]

Adv Respir Med
Griffo R, Jasuja JK, Niedermaier B, Wege S, Shala J, Deissner H, Brendel L, Rösch RM, Eichhorn F, Allgäuer M, Tong E, Wimmer C, Eichhorn ME, Winter H, Klotz LV.   +14 more
europepmc   +1 more source

The Scope of Microbiology

Academic Medicine, 1955
openaire   +3 more sources

Secondary Site Ligand for Integrin αVβ3 Enables Targeted mRNA Delivery

Angewandte Chemie, EarlyView.
Non‐orthosteric, low‐affinity ligands for integrin αVβ3, identified by fragment screening, achieve superselective nanoparticle targeting (ακ ≈ 3) of αVβ3‐overexpressing endothelial cells. Unlike traditional arginine–glycine–aspartate decorated particles, these fragment‐functionalized LNPs discriminate cells by receptor density and deliver mRNA to ...
Sebastian Bayer, María García‐García, Raffaele Senatore, Maria Stratoudaki, Alina Markhof, Angelika Berger‐Becvar, Anna Sophia Parianou, Christoph Rademacher   +7 more
wiley   +1 more source

Multivariate Assessment of Microbiological and Incubation Data from an Experimental Trial Evaluating Essential Oil-Based Sanitizers and Formaldehyde on Hatching Eggs. [PDF]

Pathogens
Dos Santos VM, Oliveira GDS, McManus C.
europepmc   +1 more source