Results 231 to 240 of about 410,576 (311)

Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron

Angewandte Chemie, EarlyView.
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej, Arturo Rodríguez‐Banqueri, Danuta Mizgalska, Borys Szmigielski, Zuzanna Nowakowska, Małgorzata Benedyk‐Machaczka, Monika Bzowska, Katarzyna Mikruta, Juan Sebastián Ramírez‐Larrota, Chinanu Agunanne, Olivier Julien, Anthony J. O'Donoghue, Carsten Scavenius, Mario López‐Martín, Enrique Marcos, Łukasz Koziej, Sebastian Glatt, Pablo Guerra, Ulrich Eckhard, Jan Potempa, F. Xavier Gomis‐Rüth   +20 more
wiley   +1 more source

Does Diabetes Influence the Microbiological Response to Non-Surgical Periodontal Therapy? A Systematic Review. [PDF]

Dent J (Basel)
Talapaneni S, Jamieson L, Nath S.
europepmc   +1 more source

dsRADAR: Imaging and Detecting Cellular dsRNA by Repurposing RNA‐Binding Proteins

Angewandte Chemie, EarlyView.
Double‐stranded RNA (dsRNA) plays an important role in the innate immune system, but can be misregulated in disease, leading to inflammation. Despite the importance of this motif, methods for detecting dsRNA remain limited. This work shows that ADAR3 can be repurposed to provide improved detection of dsRNA, which is demonstrated in the context of viral
Weina Cheng, Tyson D. Todd, Alexandria L. Quillin, Harshad Ingle, Angela M. Halstead, Megan T. Baldridge, José B. Sáenz, Jennifer M. Heemstra   +7 more
wiley   +1 more source

Structured clinical adjudication of <i>Streptomyces</i> spp. recovered from bronchoalveolar lavage in severe COVID-19 ARDS complicated by polymicrobial lower respiratory tract infection during invasive mechanical ventilation: a case report. [PDF]

Front Med (Lausanne)
Briones-Claudett KH, Solís JB, Mendoza MFP, Barberan-Torres P, Márquez DCB, Parreno C, Asqui I, Briones-Zamora AD, Briones-Zamora KH.   +8 more
europepmc   +1 more source

Beyond Foodborne Pathogens: An Integrated Assessment of the Microbiological Safety of Bulgarian White Brined Cheese. [PDF]

Foods
Ermenlieva N, Stamova S, Ibryamova S, Ivanova N, Atanasova P, Marinova V, Tsankova G, Georgieva E.   +7 more
europepmc   +1 more source

Industrial-Scale Production of Additive-Free Organic Salami Without Nitrite Curing Salt: Process Design and Technological Performance. [PDF]

Foods
Bühler S, Ploeger A, Vogtmann H.
europepmc   +1 more source

Beyond the Pocket: Clinical, Routine Biomarker, and Microbiological Associations with Systemic Versus Localized Cardiovascular Implantable Electronic Device Infection. [PDF]

Diagnostics (Basel)
Karamanlıoğlu D, Akdoğan M, Özdemir Ö, Sunman H, Efe TH, Algül E, Tunca Ç, Kul G, Gürbüz Y, Karamanlıoğlu M.   +9 more
europepmc   +1 more source

Long-term control of <i>Legionella pneumophila</i> and <i>Pseudomonas aeruginosa</i> in dental unit waterlines following optimization of a hypochlorous acid-based water safety program. [PDF]

Front Oral Health
Wolf A, Abdullah TEA, Moritz A, Georgopoulos A.   +3 more
europepmc   +1 more source