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Microbiome and Malignancy [PDF]
Cell Host & Microbe, 2011 Current knowledge is insufficient to explain why only a proportion of individuals exposed to environmental carcinogens or carrying a genetic predisposition to cancer develop disease. Clearly, other factors must be important, and one such element that has recently received attention is the human microbiome, the residential microbes including Bacteria ...
Claudia S. Plottel, Martin J. Blaser
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The microbiome in bronchiectasis [PDF]
European Respiratory Review, 2019 Bronchiectasis is increasing in prevalence worldwide, yet current treatments available are limited to those alleviating symptoms and reducing exacerbations. The pathogenesis of the disease and the inflammatory, infective and molecular drivers of disease progression are not fully understood, making the development of novel treatments challenging ...
Richardson, Hollian +3 more
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Microbiome, 2019 The National Institutes of Health (NIH) is the primary federal government agency for biomedical research in the USA. NIH provides extensive support for human microbiome research with 21 of 27 NIH Institutes and Centers (ICs) currently funding this area ...
NIH Human Microbiome Portfolio Analysis Team
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Scientific Reports, 2022 Mycobacterium tuberculosis (M. tb), the etiological agent of tuberculosis (TB), poses a severe challenge for public health and remains the number one cause of death as a single infectious agent.
Md Abdur Rahim +7 more
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Genome Biology, 2013 Plant genomes contribute to the structure and function of the plant microbiome, a key determinant of plant health and productivity. High-throughput technologies are revealing interactions between these complex communities and their hosts in unprecedented detail.
Turner, T, James, E, Poole, P
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Interpersonal variability of the human gut virome confounds disease signal detection in IBD
Communications Biology, 2023 A longitudinal analysis of unamplified fecal virome of healthy controls and IBD patients reveals interpersonal variability is a factor that limits our ability to identify associations between the virome composition and IBD.
Stephen R. Stockdale +15 more
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Microbiome, 2019 The National Institutes of Health (NIH) organized a three-day human microbiome research workshop, August 16–18, 2017, to highlight the accomplishments of the 10-year Human Microbiome Project program, the outcomes of the investments made by the 21 NIH ...
The 2017 NIH-wide microbiome workshop writing team
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Establishing What Constitutes a Healthy Human Gut Microbiome: State of the Science, Regulatory Considerations, and Future Directions. [PDF]
, 2019 On December 17, 2018, the North American branch of the International Life Sciences Institute (ILSI North America) convened a workshop "Can We Begin to Define a Healthy Gut Microbiome Through Quantifiable Characteristics?" with >40 invited academic ...
Antonopoulos +177 more
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Is There a Brain Microbiome? [PDF]
Neuroscience Insights, 2021 Numerous studies have identified microbial sequences or epitopes in pathological and non-pathological human brain samples. It has not been resolved if these observations are artifactual, or truly represent population of the brain by microbes. Given the tempting speculation that resident microbes could play a role in the many neuropsychiatric and ...
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Choice of assembly software has a critical impact on virome characterisation
Microbiome, 2019 Background The viral component of microbial communities plays a vital role in driving bacterial diversity, facilitating nutrient turnover and shaping community composition.
Thomas D. S. Sutton +4 more
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