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microbiomeMarker: an R/Bioconductor package for microbiome marker identification and visualization

open access: yesBioinform., 2022
SUMMARY Characterizing biomarkers based on microbiome profiles has great potential for translational medicine and precision medicine. Here, we present microbiomeMarker, an R/Bioconductor package implementing commonly used normalization and differential ...
Yang Cao   +5 more
semanticscholar   +1 more source

Discordant transmission of bacteria and viruses from mothers to babies at birth [PDF]

open access: yes, 2019
BACKGROUND: The earliest microbial colonizers of the human gut can have life-long consequences for their hosts. Precisely how the neonatal gut bacterial microbiome and virome are initially populated is not well understood.
Handley, Scott A   +8 more
core   +2 more sources

2017 NIH-wide workshop report on “The Human Microbiome: Emerging Themes at the Horizon of the 21st Century”

open access: yesMicrobiome, 2019
The National Institutes of Health (NIH) organized a three-day human microbiome research workshop, August 16–18, 2017, to highlight the accomplishments of the 10-year Human Microbiome Project program, the outcomes of the investments made by the 21 NIH ...
The 2017 NIH-wide microbiome workshop writing team
doaj   +1 more source

Metagenomic analysis of mother-infant gut microbiome reveals global distinct and shared microbial signatures

open access: yesGut Microbes, 2021
Emerging evidence indicates maternal microbiota as one major reservoir for pioneering microbes in infants. However, the global distinct and identical features of mother–infant gut microbiota at various taxonomic resolutions and metabolic functions across
Shaopu Wang   +10 more
doaj   +1 more source

Akkermansia muciniphila reduces susceptibility to Listeria monocytogenes infection in mice fed a high-fat diet

open access: yesGut Microbes, 2023
A high-fat (HF) diet reduces resistance to the foodborne pathogen Listeria monocytogenes. We demonstrate that short-term gavage with A. muciniphila increases resistance to oral and systemic L. monocytogenes infection in mice fed a HF diet. A. muciniphila
Jonathan M. Keane   +10 more
doaj   +1 more source

Evaluation of the cutaneous microbiome in psoriasis [PDF]

open access: yes, 2010
Psoriasis, a highly prevalent disease of humans of unknown cause, is a chronic inflammatory disorder primarily involving skin, with distinctive clinical characteristics.
Alexander Alekseyenko   +5 more
core   +2 more sources

Choice of assembly software has a critical impact on virome characterisation

open access: yesMicrobiome, 2019
Background The viral component of microbial communities plays a vital role in driving bacterial diversity, facilitating nutrient turnover and shaping community composition.
Thomas D. S. Sutton   +4 more
doaj   +1 more source

Alpha-synuclein alters the faecal viromes of rats in a gut-initiated model of Parkinson’s disease

open access: yesCommunications Biology, 2021
Stockdale et al. assess longitudinal faecal virome changes in a rat model of Parkinson’s Disease (PD) in which either monomeric or preformed fibrils (PFF) of α-synuclein were administered directly into their enteric nervous system.
Stephen R. Stockdale   +8 more
doaj   +1 more source

Diet rapidly and reproducibly alters the human gut microbiome

open access: yesNature, 2013
Long-term dietary intake influences the structure and activity of the trillions of microorganisms residing in the human gut, but it remains unclear how rapidly and reproducibly the human gut microbiome responds to short-term macronutrient change. Here we
Lawrence A. David   +12 more
semanticscholar   +1 more source

Establishing What Constitutes a Healthy Human Gut Microbiome: State of the Science, Regulatory Considerations, and Future Directions. [PDF]

open access: yes, 2019
On December 17, 2018, the North American branch of the International Life Sciences Institute (ILSI North America) convened a workshop "Can We Begin to Define a Healthy Gut Microbiome Through Quantifiable Characteristics?" with >40 invited academic ...
Antonopoulos   +177 more
core   +2 more sources

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