Results 201 to 210 of about 969,825 (379)

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Periodontitis-associated salivary microbiota exacerbates systemic osteoclastogenesis via gut modulation and tryptophan metabolism suppression in ovariectomized mice. [PDF]

Int J Oral Sci
Wang N, Qian J, Wang M, Li L, Liao W, Chen R, Nie H, Ge R, Sun F, Yan F.   +9 more
europepmc   +1 more source

Narrative Review: Gut Microbiota and Its Impact on α‐syn Function in Parkinson's Disease [PDF]

Isidro Daniel Salinas-Velarde, Juan Manuel Donaciano‐Domínguez, Rigoberto Oros‐Pantoja, José Félix Aguirre‐Garrido, Rina María González‐Cervantes, Jacobo Esteban Munguía‐Cervantes, Modesto Gómez López, Jaime Bustos‐Martínez, Alexandra Estela Soto‐Piña   +8 more
openalex   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Preventive Effect of Peptidoglycan Extracted from Lactobacillus casei ATCC 393 on Dextran Sulfate Sodium-Induced Inflammation in Mice Through Gut Microbiota Regulation [PDF]

Ruiyi Li, Jing Sun, Yao Xu, Min Xu, Huazhi Xiao, Weiwei Hong, Ye Han   +6 more
openalex   +1 more source

Microbiota alters behaviour [PDF]

Nature Reviews Endocrinology, 2018
openaire   +2 more sources

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

Proceedings of the National Academy of Sciences of the United States of America, 2010
M. Dominguez-Bello, E. Costello, M. Contreras, M. Magris, G. Hidalgo, N. Fierer, R. Knight   +6 more
semanticscholar   +1 more source

MicrobeDiscover: A Knowledge Graph–Enabled AI Framework for Identifying Microbes for Inorganic Nanomaterial Biosynthesis

Advanced Science, EarlyView.
Microbial synthesis of nanomaterials (NMs) is eco‐friendly, but the screening of microorganisms is limited by inefficient traditional methods (currently only involving∽400 microorganisms/90 NMs). We propose AI framework MicrobeDiscover, integrating a knowledge graph of microbe‐NM interactions.
Ludi Wang, Hexing Han, Yufeng Liu, Zhiyuan Ning, Yujie Ma, Haidan Wang, Jinling Xu, Qiansheng Huang, Wenjuan Cui, Yuanchun Zhou, Yang Gao, Bin Wang, Yi Du   +12 more
wiley   +1 more source

Improving ulcerative colitis prospects through fecal microbiota transfer: atypical donor microbiota can boost success rate. [PDF]

Gut Microbes
van de Guchte M, Mondot S, Cadiou J, Raghuvanshi R, Rous C, Doré J.   +5 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source