Results 1 to 10 of about 312,257 (139)

Role of the Spore Coat Proteins CotA and CotB, and the Spore Surface Protein CDIF630_02480, on the Surface Distribution of Exosporium Proteins in Clostridioides difficile 630 Spores

Microorganisms, 2022
Clostridioides difficile is Gram-positive spore-former bacterium and the leading cause of nosocomial antibiotic-associated diarrhea. During disease, C. difficile forms metabolically dormant spores that persist in the host and contribute to recurrence of ...
Nicolás Montes-Bravo, Alba Romero-Rodríguez, José García-Yunge, César Medina, Marjorie Pizarro-Guajardo, Daniel Paredes-Sabja   +5 more
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Respiratory Heme A-Containing Oxidases Originated in the Ancestors of Iron-Oxidizing Bacteria

Frontiers in Microbiology, 2021
Respiration is a major trait shaping the biology of many environments. Cytochrome oxidase containing heme A (COX) is a common terminal oxidase in aerobic bacteria and is the only one in mammalian mitochondria. The synthesis of heme A is catalyzed by heme
Mauro Degli Esposti, Ana Moya-Beltrán, Ana Moya-Beltrán, Raquel Quatrini, Raquel Quatrini, Raquel Quatrini, Lars Hederstedt   +6 more
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Analysis of colonic mucosa-associated microbiota using endoscopically collected lavage

Scientific Reports, 2022
The bacterial composition of the gut lumen and mucosa is distinct and the mucosa-associated bacteria are thought to play a more critical role in interactions with the host immune system.
Eiji Miyauchi, Takashi Taida, Masami Kawasumi, Toshifumi Ohkusa, Nobuhiro Sato, Hiroshi Ohno   +5 more
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Characterization of Exosporium Layer Variability of Clostridioides difficile Spores in the Epidemically Relevant Strain R20291

Frontiers in Microbiology, 2020
Clostridioides difficile is a Gram-positive anaerobic intestinal pathogenic bacterium and the causative agent of antibiotic-associated diarrhea. C. difficile spore is a dormant state which acts as a vehicle of transmission and infection. In C.
Marjorie Pizarro-Guajardo, Marjorie Pizarro-Guajardo, Paulina Calderón-Romero, Alba Romero-Rodríguez, Alba Romero-Rodríguez, Daniel Paredes-Sabja, Daniel Paredes-Sabja   +6 more
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The effectiveness and safety of vedolizumab induction for moderate to severe ulcerative colitis for Asia patient: A real practice observational study

Journal of the Formosan Medical Association, 2022
Background: The use of biologic agents has become the cornerstone of therapy for moderate to severe IBD. Few studies have investigated the efficacy of vedolizumab (VDZ) induction for ulcerative colitis (UC) in Asian patients in a real practice setting ...
Chia-Jung Kuo, Puo-Hsien Le, Wei-Chen Tai, Keng-Liang Wu, Hsu-Heng Yen, Chih-Wei Yen, Shui-Yi Tung, Chen-Shuan Chung, Ming-Yao Su, Cheng-Tang Chiu   +9 more
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The early life microbiota protects neonatal mice from pathological small intestinal epithelial cell shedding [PDF]

, 2020
The early life gut microbiota plays a crucial role in regulating and maintaining the intestinal barrier, with disturbances in these communities linked to dysregulated renewal and replenishment of intestinal epithelial cells.
Alastair J. M. Watson, Cristina Alcon‐Giner, d'Hennezel E, Federico Bernuzzi, Gwénaëlle Le Gall, Hedblom GA, Kevin R. Hughes, Lindsay J. Hall, Lisa Chalklen, Matthew J. Dalby, Potten CS, Selma‐Royo M, Shabhonam Caim, Weiser MM, Zoe Schofield   +14 more
core   +1 more source

Updating changes in human gut microbial communities associated with Clostridioides difficile infection

Gut Microbes, 2021
Clostridioides difficile is the causative agent of antibiotic-associated diarrhea, a worldwide public health problem. Different factors can promote the progression of C.
Giovanny Herrera, Daniel Paredes-Sabja, Manuel Alfonso Patarroyo, Juan David Ramírez, Marina Muñoz   +4 more
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The chaperone ClpC participates in sporulation, motility, biofilm, and toxin production of Clostridioides difficile

Journal of Global Antimicrobial Resistance, 2023
: Objectives: Clostridioides difficile is a nosocomial pathogen that is associated with the use of antibiotics. One of the most worrying aspects of C. difficile infection is its ability to resist antimicrobial therapies, owing to spore formation.
Camila Queraltó, Constanza Ortega, Fernando Díaz-Yáñez, Osvaldo Inostroza, Giovanni Espinoza, Ricardo Álvarez, Ruth González, Francisco Parra, Daniel Paredes-Sabja, Lillian G. Acuña, Iván L. Calderón, Juan A. Fuentes, Fernando Gil   +12 more
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Probiotic Yeasts and Vibrio anguillarum Infection Modify the Microbiome of Zebrafish Larvae

Frontiers in Microbiology, 2021
The host microbiome plays an essential role in health and disease. Microbiome modification by pathogens or probiotics has been poorly explored especially in the case of probiotic yeasts.
Orlando Vargas, María Soledad Gutiérrez, María Soledad Gutiérrez, Mario Caruffo, Benjamín Valderrama, Daniel A. Medina, Daniel A. Medina, Katherine García, Angélica Reyes-Jara, Magaly Toro, Carmen G. Feijóo, Carmen G. Feijóo, Paola Navarrete, Paola Navarrete   +13 more
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Dietary Derived Micronutrients Modulate Immune Responses Through Innate Lymphoid Cells

Frontiers in Immunology, 2021
Innate lymphoid cells (ILCs) are a group of innate immune cells that possess overlapping features with T cells, although they lack antigen-specific receptors.
Zhengzheng Shi, Zhengzheng Shi, Hiroshi Ohno, Hiroshi Ohno, Hiroshi Ohno, Hiroshi Ohno, Naoko Satoh-Takayama, Naoko Satoh-Takayama   +7 more
doaj   +1 more source