Results 121 to 130 of about 844,915 (312)

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

Intestinal microbiota and HIV-1 infection [PDF]

, 2007
The intestinal microbiota consists of a qualitatively and quantitatively diverse range of microorganisms dynamically interacting with the host. It is remarkably stable with regard to the presence of microorganisms and their roles which, however, can be ...
Lopes, C. A M, Pereira, Paulo Câmara Marques, Trindade, Erasmo Benício Santos de Moraes, E. B. S. M. Trindade, Souza, L. R., P. C. M. Pereira, Lopes, C. A M [UNESP], Souza, L. R. [UNESP], C. A. M. Lopes, L. R. Souza, Pereira, Paulo Câmara Marques [UNESP]   +10 more
core   +1 more source

Intestinal Microbiota in Sepsis

, 2022
Sepsis is defined as a life-threatening organ dysfunction, which is caused by a dysregulated host response to infection. The composition of the intestinal microbiota is significantly different between patients with sepsis and healthy individuals ...
Lexin Wang, Haibo Zhang, Tongwen Sun
core   +1 more source

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

Advanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang   +9 more
wiley   +1 more source

Unraveling piglet gut microbiota dynamics in response to feed additives [PDF]

, 2010
Keywords: GI tract, microbiota, pig, PITChip, weaning The gastrointestinal (GI) tract of pigs is colonized by a dense and metabolically active microbiota, comprising mainly bacteria, that have not only a commensal but a symbiotic (beneficial for both ...
Perez-Gutierrez, O.N.
core  

Dietary calcium decreases but short-chain fructo-oligosaccharides increase colonic permeability in rats [PDF]

, 2010
An increased intestinal permeability is associated with several diseases. Nutrition can influence gut permeability. Previously, we showed that dietary Ca decreases whereas dietary short-chain fructo-oligosaccharides (scFOS) increase intestinal ...
Schepens, M.A.A., Schepens, Marloes A. A.,, Bovee-Oudenhoven, I.M.J., Brummer, R.J.M., Willemsen, Linette E. M.,, Rijnierse, A., Bovee-Oudenhoven, Ingeborg M. J.,, Schonewille, A.J., Vink, C., Arjan J. Schonewille, Rijnierse, Anneke,, Willemsen, L.E.M., Anneke Rijnierse, Carolien Vink, Marloes A. A. Schepens, Meer, R., van de, Willemsen, L. E., Linette E. M. Willemsen, Vink, Carolien,, Bovee Oudenhoven, I.M., Brummer, R.J., Brummer, Robert,, Roelof van der Meer, van der Meer, Roelof,, van der Meer, R., Ingeborg M. J. Bovee-Oudenhoven, Robert-Jan M. Brummer, Schonewille, Arjan J.,   +27 more
core   +1 more source

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

Advanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie, Mai Ye, Xuexia Liu, Jing Wang, Ying Chen, Lu Tan, Jinheng Fu, Xiaochang Huang   +7 more
wiley   +1 more source

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

Advanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai, Qinyong You, Gao Si, Daole Hu, Ao Sun, Shilong Su, Ruideng Wang, Jixing Fan, Shan Gao, Tengjiao Zhu, Chun‐Li Song, Fang Zhou, Yang Lv   +12 more
wiley   +1 more source

Research progress of traditional Chinese medicine on the treatment of diarrhea by regulating intestinal microbiota and its metabolites based on renal-intestinal axis

Frontiers in Cellular and Infection Microbiology
Intestinal microbiota and its metabolites are involved in many physiological processes of the human body and play a vital role in maintaining human health. The occurrence of kidney disease can cause intestinal microbiota imbalance, resulting in diarrhea.
Tong Zhou, Tong Zhou, Yifan Zhang, Zhaoyuan Li, Chunfeng Lu, Chunfeng Lu, Hong Zhao   +6 more
doaj   +1 more source

HISTAMIN RELEASE FROM INTESTINAL MICROBIOTA IN CHILDREN WITH ATOPIC DERMATITIS

Детские инфекции (Москва), 2016
The purpose of the study is to determine the features of the formation of the intestinal microbiota, its role of histamin release in children with atopic dermatitis.
S. Yu. Nosyreva, L. A. Lityaeva
doaj   +1 more source