Results 61 to 70 of about 4,769 (218)

Markers of placental function correlate with prevalence and quantity of nucleated fetal cells in maternal circulation in normotensive term pregnancies

Acta Obstetricia et Gynecologica Scandinavica, 2023
Introduction Transplacental fetal cell transfer results in the engraftment of fetal‐origin cells in the pregnant woman's body, a phenomenon termed fetal microchimerism.
Heidi E. Fjeldstad, Daniel P. Jacobsen, Guro M. Johnsen, Meryam Sugulle, Angel Chae, Sami B. Kanaan, Hilary S. Gammill, Anne Cathrine Staff   +7 more
doaj   +1 more source

Fetal Cells Homing in Maternal Bony Defects: A Preliminary in vivo Investigation

Regeneration, Reconstruction & Restoration, 2019
Introduction: Fetal cells are present in maternal tissue during pregnancy as well as post-partum. Although their clinical significance is not clear, these cells can be found in injured, diseased and normal tissue.
Sepanta Hosseinpour, Saeed Reza Motamedian, Seyyed Mehrshad Jafari, Sara Soudi, Masoud Soleimani, Arash Khojasteh   +5 more
doaj   +1 more source

Feto-maternal microchimerism: Memories from pregnancy

iScience, 2022
Summary: There is a bidirectional transplacental cell trafficking between mother and fetus during pregnancy in placental mammals. The presence and persistence of fetal cells in maternal tissues are known as fetal microchimerism (FMc).
Blanca Cómitre-Mariano, Magdalena Martínez-García, Bárbara García-Gálvez, María Paternina-Die, Manuel Desco, Susanna Carmona, María Victoria Gómez-Gaviro   +6 more
doaj   +1 more source

Cellular Fetal Microchimerism in Preeclampsia [PDF]

Hypertension, 2013
Previous studies have shown elevated concentrations of free fetal DNA and erythroblasts in maternal circulation in women with preeclampsia compared with those with normal pregnancy. Pluripotent and immunocompetent fetal cells also transfer to the maternal circulation during pregnancy, but whether concentrations of fetal mononuclear cells ...
Hilary S, Gammill, Tessa M, Aydelotte, Katherine A, Guthrie, Evangelyn C, Nkwopara, J Lee, Nelson   +4 more
openaire   +2 more sources

UK recommendations for chimerism testing and monitoring following allogeneic haematopoietic stem cell transplantation (HSCT): Best practice consensus guidelines from the British Society for Blood and Marrow Transplant and Cellular Therapies (BSBMTCT), NHS England Genomic Laboratory Hub (GLH) Haematological Malignancies Working Group, UK Cancer Genetics Group (UKCGG) and the UK National External Quality Assessment Service for Leucocyte Immunophenotyping (UK NEQAS LI)

British Journal of Haematology, Volume 207, Issue 5, Page 1802-1814, November 2025.
Summary In allogeneic haematopoietic stem cell transplantation (HSCT), important clinical decisions depend upon assessment of chimerism, including immunosuppressant dosing and donor lymphocyte infusions (DLI), which in turn can have major impacts on disease control, graft‐versus‐host disease (GVHD), immunity and ultimately patient survival.
Andrew Clark, Hazel Clouston, Kanchan Rao, Najeem Folarin, Josu De la Fuente, Angela Hamblin, Eduardo Olavarria, Debbie Richardson, Polly Talley, Victoria Potter, Justin Loke, Terri McVeigh, John Snowden   +12 more
wiley   +1 more source

Infusion of donor leukocytes to induce tolerance in organ allograft recipients [PDF]

, 1999
To further enhance chimerism, 229 primary allograft recipients have received perioperative intravenous infusion of a single dose of 3 to 6 x 108 unmodified donor bone marrow (BM) cells/kg body weight.
Abu-Elmagd, K, Corry, R, Dodson, F, Fung, JJ, Griffith, B, Jordan, M, Keenan, R, McCurry, K, Ostrowski, L, Pham, S, Rao, AS, Reyes, J, Salgar, SK, Sesky, T, Shapiro, R, Starzl, TE, Zeevi, A   +16 more
core   +1 more source

Fetal Microchimerism and Cancer [PDF]

Cancer Research, 2008
Abstract The persistence of fetal stem cells with multilineage potential in women who have been pregnant, a phenomenon known as fetal microchimerism, is emerging as a potential contributing factor in certain diseases, including cancer. For example, fetal microchimerism has been implicated in autoimmune disease, wound healing, and cancer.
openaire   +2 more sources

Assessment of Donor‐Specific Human Leukocyte Antigen Antibodies Following Pediatric Liver Transplantation: Predictors, Protectors, and Clinical Relevance

Clinical Transplantation, Volume 39, Issue 11, November 2025.
ABSTRACT Background Following pediatric liver transplantation (pLT), the significance and management of donor‐specific antibodies (DSA) against human leukocyte antigen (HLA) remain undefined. The aim of this single‐center study was to investigate the occurrence of DSA, their clinical impact on predictors for and protectors against DSA.
Evelien Kanaan, Sinja Ohlsson, Simone Kathemann, Benas Prusinskas, Sofia Tsaka, Falko M. Heinemann, Andreas Heinold, Maren Schulze, Lars Pape, Elke Lainka   +9 more
wiley   +1 more source

Detection of Pig Cells Harboring Porcine Endogenous Retroviruses in Non-Human Primate Bladder After Renal Xenotransplantation

Viruses, 2019
Pigs are used as potential donor animals for xenotransplantation. However, porcine endogenous retrovirus (PERV), shown to infect both human and non-human primate (NHP) cells in vitro, presents a risk of transmission to humans in xenotransplantation.
Yoonki Heo, Yeondong Cho, Keon Bong Oh, Ki Hoon Park, Hansam Cho, Hanul Choi, Minjee Kim, Ik Jin Yun, Hee Jung Lee, Young Bong Kim   +9 more
doaj   +1 more source

Cell migration and chimerism after whole‐organ transplantation: The basis of graft acceptance [PDF]

, 1993
Improvements in the prevention or control of rejection of the kidney and liver have been largely interchangeable ( 1 , 2 ) and then applicable, with very little modification, to thoracic and other organs.
Demetris, AJ, Fung, JJ, Ildstad, S, Kocova, M, Murase, N, Nalesnik, M, Ramos, H, Ricordi, C, Rudert, WA, Starzl, TE, Todo, S, Trucco, M, Tzakis, A, Zeevi, A   +13 more
core   +1 more source